ID A0A093YJ99_9PEZI Unreviewed; 1523 AA.
AC A0A093YJ99;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=O988_01892 {ECO:0000313|EMBL:KFY02803.1};
OS Pseudogymnoascus sp. VKM F-3808.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFY02803.1, ECO:0000313|Proteomes:UP000029329};
RN [1] {ECO:0000313|EMBL:KFY02803.1, ECO:0000313|Proteomes:UP000029329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFY02803.1,
RC ECO:0000313|Proteomes:UP000029329};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY02803.1}.
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DR EMBL; JPJR01000300; KFY02803.1; -; Genomic_DNA.
DR STRING; 1391699.A0A093YJ99; -.
DR HOGENOM; CLU_000335_0_4_1; -.
DR Proteomes; UP000029329; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004179; Sec63-dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000029329}.
FT DOMAIN 284..458
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 498..686
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 26..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 170..247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1208..1229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1296..1320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1468..1497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 28..65
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 206..236
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1208..1227
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1296..1311
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1523 AA; 169519 MW; A2795B81E87F95D1 CRC64;
MDPRMQRIID NASLNVQDDV YPIVPFSRAN TQPPSQSSFS RHFSDDSSLQ DVFSFRPSQQ
QVPRPQYGAD VFDRQGGQSD AMQQHGIGAP RISLTPRSLL TANGSTAAGD DALHTYGIPN
GAHRIANSAS TLANLRTQPP SIRITQPPSS PDNSSIFPYA ANRFSQLQPL RQQPSPPFHL
TGHSFTPPRY RSPSPNLPVS SPTRRIVSRR EARASQRARS PEPQPIREEK SPHETPNPRG
AFDLSHAPPM INGIQLVSTR ELPDRFRPIF PFPLFNAVQS KVFPAAYRSD DNLVVSAPTG
GGKTAILELA IVRLIESHSS GQFKIVYQAP TKSLCSERAR DWGVKFGNLN IATAELTGDT
DAAEMRKVGN ATIIVTTPEK WDSITRKWKD YIKLLQLVKL FLIDEVHILK ESRGATLEAV
VSRMKSIGVN VRFVALSATV PNSHDIAAWL GKDHTNGHLP AHRETFGEEF RPVKLQKHVH
GFDSHINDFA FDSFLDGKLP TLIAKYTHKK PIIVFCFTRK SCENTAAKLA EWWANSRAVD
RAWPSPTARV PVSSKDLQDL TSRGISYHHA GLEPADRMAI EKAYLNGQIS VICCTSTLAV
GINLPCHLVV LKGTVGYQDG GLAEYSDLEA MQMLGRAGRP QFDDSAVAII MTRQSSIDRY
KRMISGQDVL ESTLHLNLIE HLNSEIGLGT VHNLYSAKHW LAGTFMSVRM KQNPTYYKFS
CDTGSRDPDE RLEQVCERDI KMLQDTKLVT SDQRFACTEY GQAMSKYMVK FETMQLLLSI
PEHAGVGQML HIISQASEFK DLRMKPTERG AFREFNKSPF IKYPIKENVS TTAHKISLII
QAQLGGLDTP NDKEFNRRQY QMDKAIVFER IHRLVRCVVD CKAVDCDALA TQNALELSRS
ISAEYWEHLP LQLRQIPNIG PAAFKKMVTA GINSVEKLIA SDSATIERVL TRNPPFGHKL
LETLKAFPRL TLTAEVMGRI VKSGQLPKVK IRALLGLKNQ KAPFWRHRQI SLSFVAGISN
GNLAHFWRGN IKNLEKGLEV HFATELSNPS DAISCFLACD EIIGTVQSVI LAPNIPDSLF
PVIRPSQKVV TPKVILGTDD GGGDSDADFE WDDDIADHDL IAAVKSAEES VGHTADDNTL
PDQFIDIEDI AHQQTTAPEE NEDAERPESV QMANGKWTCN HICRGGNALK NGKTCKHKCC
HDGLDKPRKL QKKTKQDASK ETKKAPEEVV GANVSKSVDK LMSQRLACND FDKDDHRIDD
VEIIDLSENL PPVPYEAVAP KDYRKLHALH SNVSNSEPVQ TLRNNKPLAQ YGNGRNPYDA
FLEKSDPKVD VEGDDLSGDD LPSPSWLVEQ SDASAADAYP GYMADLADAG SPFGDFGDDT
PDSLFYEAEQ MSRAEKPREA EETHEIEQMP EVTSSFVDAV VDYDGYTASR DLESLADPMS
LKRGPTDLLQ LPAKRVRVDD RLRDEQSRFA SSEINSETEV YDRTEEETEE QLSPRKEVTR
PEWLGEFDAD LVAMFEEAVD FAL
//
