ID A0A093YQW4_9PEZI Unreviewed; 679 AA.
AC A0A093YQW4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=protein-L-isoaspartate(D-aspartate) O-methyltransferase {ECO:0000256|ARBA:ARBA00011890};
DE EC=2.1.1.77 {ECO:0000256|ARBA:ARBA00011890};
GN ORFNames=V492_07224 {ECO:0000313|EMBL:KFY07351.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY07351.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY07351.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY07351.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily. L-
CC isoaspartyl/D-aspartyl protein methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005369}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY07351.1}.
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DR EMBL; JPJU01002583; KFY07351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YQW4; -.
DR STRING; 1420902.A0A093YQW4; -.
DR HOGENOM; CLU_350590_0_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0004719; F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0036211; P:protein modification process; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000682; PCMT.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11579; PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11579:SF0; PROTEIN-L-ISOASPARTATE(D-ASPARTATE) O-METHYLTRANSFERASE; 1.
DR Pfam; PF01135; PCMT; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 31..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..679
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 60..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 358
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 679 AA; 75370 MW; 3FA21D306975DF14 CRC64;
MYIPIANLEV RQASADDAAA SPQPNCMSGG SIAGIVIGCI AGTLLLVWLW SSLRRNTTDE
GYRGGAVATS SRPYDGRRRR RRHSSAGGRP VSRSYSTYET TERPARVDRG QYCPHHTSAY
EDSPQPIGWR ATISAPHMHA SALESLFPSV CSSTTGYPAD RAMRVLDVGS GSGYLTHVMA
ELAGADGKVV GIEHIKELAE LGKENMGKSA EGAALLESGK VRFVVGDGRK GWVEPGIEGK
GVGQETWDEK GWDAIHVGAG AAHLHDELVA QLRRPGRMFI PVDDATTGIG QHIWIVDKDT
KGVVKKKQLY RPGGLHPVAL GDTFDDERYT VVHKLGNGGF STVWVAYDDV RCEWVALKIM
TAAMTETSRE VRWFDTLAES RPESESSKYI VRLLDRFIID GPNGKHMALA FELLGPNLRS
AVKTKFPGRD DIDPSTTFKM TEQVLKALAF IHEMGFAHGD ISTKNMAFTA KNLSKVTKER
LFEVLGEPFI ENVERIDGQP LADGIPHYLV KSATWDGWDR ECDEDFRILD FGECFVHGRE
PDIITQPGGL MPPETVLTEE FDYRVDLWRV GIAIYSFVFG GLPFYSIGDR DNLVIQMIQF
IGDLPQEWKP NFDRLRIEFK KQPLQAGDLS ADRGLDYKFK HQIQDEILQP LLPVIRGLMK
FTPSERLSAQ EALELMEST
//
