ID   A0A093YZ17_9PEZI        Unreviewed;       725 AA.
AC   A0A093YZ17;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=6-phosphofructo-2-kinase domain-containing protein {ECO:0000259|Pfam:PF01591};
GN   ORFNames=O988_00987 {ECO:0000313|EMBL:KFY04110.1};
OS   Pseudogymnoascus sp. VKM F-3808.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1391699 {ECO:0000313|EMBL:KFY04110.1, ECO:0000313|Proteomes:UP000029329};
RN   [1] {ECO:0000313|EMBL:KFY04110.1, ECO:0000313|Proteomes:UP000029329}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3808 {ECO:0000313|EMBL:KFY04110.1,
RC   ECO:0000313|Proteomes:UP000029329};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY04110.1}.
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DR   EMBL; JPJR01000163; KFY04110.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093YZ17; -.
DR   STRING; 1391699.A0A093YZ17; -.
DR   HOGENOM; CLU_006383_3_1_1; -.
DR   Proteomes; UP000029329; Unassembled WGS sequence.
DR   GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR   GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR   CDD; cd07067; HP_PGM_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR   InterPro; IPR003094; 6Pfruct_kin.
DR   InterPro; IPR013079; 6Phosfructo_kin.
DR   InterPro; IPR013078; His_Pase_superF_clade-1.
DR   InterPro; IPR029033; His_PPase_superfam.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10606:SF32; 6-PHOSPHOFRUCTO-2-KINASE 1; 1.
DR   PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR   Pfam; PF01591; 6PF2K; 2.
DR   Pfam; PF00300; His_Phos_1; 1.
DR   PRINTS; PR00991; 6PFRUCTKNASE.
DR   SMART; SM00855; PGAM; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE   4: Predicted;
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029329}.
FT   DOMAIN          176..230
FT                   /note="6-phosphofructo-2-kinase"
FT                   /evidence="ECO:0000259|Pfam:PF01591"
FT   DOMAIN          306..470
FT                   /note="6-phosphofructo-2-kinase"
FT                   /evidence="ECO:0000259|Pfam:PF01591"
FT   REGION          41..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..171
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          279..301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          527..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        52..66
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        118..166
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   725 AA;  80646 MW;  F8ED252F3C976BF3 CRC64;
     MPHFTPGAVV DNEIADRLRR QSQLSSIGKA AIMSNVVAVE TSNDNHSNET REKQPTSNGL
     VPSSSISQGL VPSLSISPGL VPPPTIPHGL VPAIPIPHGR VHHTITNGHG CGPHDAGSHT
     PSDTSIGSAP STAPSSPHLM PIRQNSGSST PRTRPPATTL NIPGMTRSRV SPDGRIAERD
     VASKLVIIMV GLPARGKSYI TKKIQRYLSW QQHNSQIFNV GNRRRVAAFA QTGPSDNAAQ
     TQPRTMLVTN TNAHPGTATA SGTMDAPTQA AHILLNGVEP GQNQDSASRD HSEEPPARVT
     PMEPLDQSAE FFDPSNARAS QVREQVAIST LDELLDYLLL QGGSAGILDA TNSTIERRKL
     LFNRVKERDS KLGILFIESI CEDQGLLEAN MRLKLSGPDY KGKDPVTSLQ DFRKRVAAYE
     SAYVPLGDYE EKNGIQYIKM IDVGRKVIHH QLKGFLSGGI ASYLTTFNLA PRQIWITRHG
     ESYDNREGKL GGNSDVTPQG RAYGAVLYNF MTQKRKDWLV EQKDKILSSS FPPQPGDNTP
     PYPESRLGEL DEKNFCIWTS MLKRSIQTAE DFEADDDYDV KNWEMLNELN AGDFERLTYE
     EIEHNFPQEF NKRKQDKLHY IYPGVGGEGY LQIISRLRDM VREIERITDH VLIIGHRSIA
     RVLMAYFMDL TRNDIADLDV PLGMLFVIEP KPYGVDFHAY KYNEESQWFD EVKDYKPHKE
     TRKGN
//