ID   A0A093Z233_9PEZI        Unreviewed;      1699 AA.
AC   A0A093Z233;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=Hydantoinase B/oxoprolinase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=V492_04620 {ECO:0000313|EMBL:KFY11154.1};
OS   Pseudogymnoascus sp. VKM F-4246.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY11154.1, ECO:0000313|Proteomes:UP000029299};
RN   [1] {ECO:0000313|EMBL:KFY11154.1, ECO:0000313|Proteomes:UP000029299}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY11154.1,
RC   ECO:0000313|Proteomes:UP000029299};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the oxoprolinase family.
CC       {ECO:0000256|ARBA:ARBA00010403}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY11154.1}.
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DR   EMBL; JPJU01001563; KFY11154.1; -; Genomic_DNA.
DR   STRING; 1420902.A0A093Z233; -.
DR   HOGENOM; CLU_002157_0_1_1; -.
DR   Proteomes; UP000029299; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR   InterPro; IPR049517; ACX-like_C.
DR   InterPro; IPR008040; Hydant_A_N.
DR   InterPro; IPR002821; Hydantoinase_A.
DR   InterPro; IPR003692; Hydantoinase_B.
DR   InterPro; IPR045079; Oxoprolinase_fam.
DR   PANTHER; PTHR11365:SF2; 5-OXOPROLINASE; 1.
DR   PANTHER; PTHR11365; 5-OXOPROLINASE RELATED; 1.
DR   Pfam; PF19278; Hydant_A_C; 1.
DR   Pfam; PF05378; Hydant_A_N; 1.
DR   Pfam; PF01968; Hydantoinase_A; 1.
DR   Pfam; PF02538; Hydantoinase_B; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029299}.
FT   DOMAIN          14..224
FT                   /note="Hydantoinase/oxoprolinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF05378"
FT   DOMAIN          243..542
FT                   /note="Hydantoinase A/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF01968"
FT   DOMAIN          652..735
FT                   /note="Acetophenone carboxylase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF19278"
FT   DOMAIN          751..1279
FT                   /note="Hydantoinase B/oxoprolinase"
FT                   /evidence="ECO:0000259|Pfam:PF02538"
FT   REGION          1565..1604
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1649..1699
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1654..1678
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1699 AA;  178338 MW;  1ED078632E6A955F CRC64;
     MAVGQHKPAA GRLRISIDRG GTFTDVHASV PGRSDIILKL LSVDPGNYQD APTEGIRRVL
     EIATGRTLPR GELLDLTPIE SLRMGTTVAT NALLERKGAR SALLITRGFK DLLVIGNQSR
     PNIFDLSVSK PDVLSEKVVE IDERITLEGY AENQHPEPIE ESENVVRGIT GEHVRIITKP
     DMEAVNAQLL KLKEEGYRSI SVVLLHSYTY PHHENLIGNA AVKMGFSVAL SSALQPMIKV
     VPRGMSATAD AYLTPVIKNY IDSISSNFQG GLASKTTRVE FMQSDGGLVD FRKFSGLKAI
     LSGPAGGVVG YAQTSYDAAE KVPVIGFDMG GTSTDVSRYS GTYDHVFETT TAGVSIQSPQ
     LDINTVAAGG GSMLFWKNGL FVVGPESASA HPGPACYRKG GPLTVTDANL FLGRLLPEYF
     PKIFGPNENE PLDVAITGQK FAELTTVINE EQKSKGRIEF TPEEVALGFL NVADESMSRP
     IRALTEARGH NTAVHNLACF GGAGGQHACS VAAVLGISRI IIHKYSSILS AYGMALADVV
     NEVQQPAADV FNDTTQDEFK SKLEALVQQS TADLESQGFS GKDIHHELYL NMRHAGTSTS
     FMILKGEDWN FASEFEKRHL IEFGFLTKDK AILVDDIRVR STGSSSNGKE KSPYMQMKEV
     VPKQISAQKS QGATKVYFGS SKGSVDTPIY KLEDLEVGSQ IKGPAMVIDK TQTIVVVPEA
     VANILERCVL IDLKEKAVVD ATFESKDTSI NPIQLSIFGN RFMSIAEQMG RTLQKTSVST
     NIKERLDFSC ALFSPDGGLV ANAPHVPVHL GSMQFAVRYQ HKYWAGKLVE GDVLVSNHPT
     CGGTHLPDIT VITPVFENGE IVFYVASRGH HADIGGSLPG SMPPTSNQLW QEGAAIEAEK
     LVSGGRFNEE RMIELLLKEP AKFEGCSGTR CLQDNLSDLR AQVAANQRGI SLINGLIKEY
     GLKCVHNYMY AIQSTAEIAV RELLKSTSEN LGSVLESVDC MDDGTPIALK VTIDATKGEA
     IFDFSGTGSE VFGNTNAPTA ITHSAIIYCL RALIKSDIPL NQGCLNPIDI RIPDHSLLSP
     SKTAGVVGGN VLTSQRITDV ILKAFRACAA SQGCCNNLTF GTGGKGVDGN HVDGFGYYET
     IAGGVGAGPT WDGQSGLHTH MTNTRITDPE IFEKRYPCIL REFSLREGSG GTGLHRGGDG
     VVRDIEFLVP VQCSILSERR SHRPYGLEGG GPGALGRNDW VRQGEDGESR INLGGKATVK
     MAKGDRIVIN TPGGGAWGSE TAEKVKTNGV QKDAFVAKGS VDSAAVVITI LVANADAATG
     SSLHHTHLQV DVLEGAPRHR ARAVSLNIHI VELLNGDIVA IDSGNPGNVA ISRRSNISLG
     NGTLHWVVVD LDTDLASSIV PAVSVTPGGA LVLVVEVDVE ALVDAPRDKA GALARKVVPA
     VGVAAGVGGV GVVVLDGAVV GGGGLGWLGC LGDGGGVALG LDVLGGAGLD VVVGDKAAIG
     GQVPDGVTAD LGAGGLAGDG DKVALGVVLL DVVGQAGARA AVNWVSGNGV GARGLSWDGD
     IGGSGTSGRG IRGGDVGGSG VSGGGIRRGS LGGGGVGGSS LGGGDVRGHN NVGWGDVGGG
     RAGVDSHSDS AAGGGRNWAL GGAFNNRNID GAAGQDRGGE EGRRGGGDVG ELHGERRSVA
     TNARATNTAT DKHRKRAWY
//