ID A0A093Z2I7_9PEZI Unreviewed; 462 AA.
AC A0A093Z2I7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Probable kinetochore protein NUF2 {ECO:0000256|ARBA:ARBA00017594};
GN ORFNames=V492_04542 {ECO:0000313|EMBL:KFY11284.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY11284.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY11284.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY11284.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Acts as a component of the essential kinetochore-associated
CC NDC80 complex, which is required for chromosome segregation and spindle
CC checkpoint activity. {ECO:0000256|ARBA:ARBA00002772}.
CC -!- SUBCELLULAR LOCATION: Chromosome, centromere, kinetochore
CC {ECO:0000256|ARBA:ARBA00004629}. Nucleus
CC {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NUF2 family.
CC {ECO:0000256|ARBA:ARBA00005498}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY11284.1}.
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DR EMBL; JPJU01001527; KFY11284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093Z2I7; -.
DR STRING; 1420902.A0A093Z2I7; -.
DR HOGENOM; CLU_025461_2_1_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0031262; C:Ndc80 complex; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 1.10.418.60; Ncd80 complex, Nuf2 subunit; 1.
DR InterPro; IPR005549; Kinetochore_Nuf2_N.
DR InterPro; IPR041112; Nuf2_DHR10-like.
DR InterPro; IPR038275; Nuf2_N_sf.
DR PANTHER; PTHR21650:SF2; KINETOCHORE PROTEIN NUF2; 1.
DR PANTHER; PTHR21650; MEMBRALIN/KINETOCHORE PROTEIN NUF2; 1.
DR Pfam; PF03800; Nuf2; 1.
DR Pfam; PF18595; Nuf2_DHR10-like; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Centromere {ECO:0000256|ARBA:ARBA00023328};
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Kinetochore {ECO:0000256|ARBA:ARBA00022838};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299}.
FT DOMAIN 28..168
FT /note="Kinetochore protein Nuf2 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03800"
FT DOMAIN 281..396
FT /note="Nuf2 DHR10-like"
FT /evidence="ECO:0000259|Pfam:PF18595"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 329..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..392
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 174..201
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 462 AA; 53408 MW; FAD9D5D35F6894DF CRC64;
MSYNPRMSMA PPPSQQKSRV TKKEEESDAF MRLPDKEIAG CISDIGVPFT AADLQKPNPL
QIQQIFQWFA ELLMNATHDT IGPAMRAAAE DVCGEYMDVV PSDVRNLMGF YMSLRKLLLE
CGVHDFSFQD LQKPTHERLS KIFSYIINFV RFRESQTGVI DEHFNKAETT KGRIETLYME
NQDMEARLEE MRRNRKAMES HVSDKVKRNQ ELKQRLRALQ VSQTEVMARY DGLQKKKDEL
THVLEDKTAT AINLRQESGK LRPYVLQSPA ALQATLTDLG ASLSNEKAHI DSLDRRARAL
QTSTDTFGVV ATDVSSVSKI LEETAAELQK EDEENVKNSR QRDALSERGN NVREVEREES
LLKRQLAKYN ERTEKLREGS REKAQAAKER MEELRAVHRT LTEERGDKGR EMERRRVRIE
QTEKKMVDLK ENIENEIHTA HDEFLKMDSH IKLYITEMEQ SL
//
