ID A0A093Z7C1_9PEZI Unreviewed; 1122 AA.
AC A0A093Z7C1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY13039.1};
GN ORFNames=V492_03520 {ECO:0000313|EMBL:KFY13039.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY13039.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY13039.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY13039.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. CAMK Ser/Thr
CC protein kinase family. CHEK2 subfamily.
CC {ECO:0000256|ARBA:ARBA00005575}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY13039.1}.
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DR EMBL; JPJU01001111; KFY13039.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093Z7C1; -.
DR STRING; 1420902.A0A093Z7C1; -.
DR HOGENOM; CLU_003637_1_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0034045; C:phagophore assembly site membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0006914; P:autophagy; IEA:UniProtKB-KW.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR PANTHER; PTHR44167; OVARIAN-SPECIFIC SERINE/THREONINE-PROTEIN KINASE LOK-RELATED; 1.
DR PANTHER; PTHR44167:SF18; SERINE_THREONINE-PROTEIN KINASE RAD53; 1.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00240; FHA; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000029299}.
FT DOMAIN 110..166
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
FT DOMAIN 280..561
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 614..634
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 757..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 846..865
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 309
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1122 AA; 124696 MW; D104E302C902BFA2 CRC64;
MDEEATQPAT QLVMDPRRLG DHVSDLEDDD LTDIFCILHP VSMSALNAVA HIGDVAPEHT
VSRASAPIKI RGEPADVTDP NTMDLAEQGL VSRDIALRLS AKLIDPLAGY TFGRNAQRCD
FVLRYPTVEG TSRISNVHFR IFITADGIVM IEDQSTNGTV VEGKKLRFKD KENDAPHKHT
LSQGSLVSLS MNAPDEDIRF VVRIPQREGI YEDLFAQNLT DYFARMTLLR KNRDAQVKTD
ATGQAPDIFA VQNYPGGNGH GADQTLISRR PKEWRGGAKY NKSRVIGKGA FATVYMISAK
YDGTIYAAKE LEKRRFVKNG ILDQKVDQEM RIMSSIRHTN IVQYIEHVDW EDHLYIIMDY
VPEGDLGSLV SSRGTLSEVS TKTLASQMFS ALKYLHDKGI THRDIKPDNI LVQSFDPFHV
KLTDFGLSKR IENEDTFMRT FCGTLLYCAP EVYSEYLSYF LDPAEVQRTK SKKFKRYDQA
VDLWSLAGVL FYCLSGSPPY PAKSGTTYQQ LLHSIMRGPL DIRPLQHAGV SEDGIKVIKS
MLHNQAPYRP SIEELELSLW LKPEGSREAE ANAHLEHTAS QLSIQEQDDS LGTSDEIDLI
NAMVDTKNLE IPSSFISGDD GSSSNGEKLN TTSNQPRLFG EVNLSALRSS GVIPQERLNL
PLSDTGDDNT AQSSFVKVDT SPIDFESQNN FYESSIIPGQ HNMPPSVVGT GTAPSLLGAE
SMVGNLAMNS PSPTTVVDVA SPQVTFTGAV PDFRESMKSL RRQRDPNGDD EPLAKRAKSS
RAIDIELSKT VFWDARDRST HHLDYPVMTN SEYQEAKALA KMYGEEFKHG ESVFETVVGA
YRRSASVTPE PPTRAQSEPV AVGGPAKLNR DERGFSEDGV APPTGSWVNG VPSPEISQYL
PNHSKAAKAV IKTEEKSVIT NDVFQPPHRI LAKLVGTSDS VLPNLTLNIT SLFTTWGRGF
DNKLRHADRT DNRVPKYALK LALWQPGTKP SSSPPTEKDN AFAFYIATKA SHGIKVNGIV
LPSHDCRSPQ MSPSKYWGKL QHGDVVDVWS QDSNPDIILR FRFDCFWGES KEPRQNGQFF
SMMREGPLKD ELESFCQWEE SAFFQAKYDA EVKAKGTKEG GK
//
