ID A0A094A0H4_9PEZI Unreviewed; 1251 AA.
AC A0A094A0H4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=C2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V493_06056 {ECO:0000313|EMBL:KFY23141.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY23141.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY23141.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY23141.1}.
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DR EMBL; JPJV01002305; KFY23141.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094A0H4; -.
DR STRING; 1420906.A0A094A0H4; -.
DR HOGENOM; CLU_002125_2_0_1; -.
DR OrthoDB; 1465207at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0061817; P:endoplasmic reticulum-plasma membrane tethering; IEA:InterPro.
DR GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR CDD; cd04041; C2A_fungal; 1.
DR CDD; cd04052; C2B_Tricalbin-like; 1.
DR CDD; cd21676; SMP_Mug190; 1.
DR Gene3D; 2.60.40.150; C2 domain; 2.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037767; C2A_Mug190-like.
DR InterPro; IPR037765; C2B_Tricalbin.
DR InterPro; IPR031468; SMP_LBD.
DR PANTHER; PTHR47348; MEIOTICALLY UP-REGULATED GENE 190 PROTEIN; 1.
DR PANTHER; PTHR47348:SF3; MEIOTICALLY UP-REGULATED GENE 190 PROTEIN; 1.
DR Pfam; PF00168; C2; 2.
DR SMART; SM00239; C2; 2.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 2.
DR PROSITE; PS50004; C2; 2.
DR PROSITE; PS51847; SMP; 1.
PE 4: Predicted;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 258..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..446
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 300..527
FT /note="SMP-LTD"
FT /evidence="ECO:0000259|PROSITE:PS51847"
FT DOMAIN 525..654
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 714..858
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 105..137
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 691..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 748..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 158..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..775
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1174..1190
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1196..1210
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1251 AA; 139074 MW; D2314D22F7AEB7DE CRC64;
MPGSSQALHF GIPEAEISNL AKPKPKFLFL VGSGSFPVKS PYFKRLLPIE TIQYWQDTAT
FTMSSGDAKF APGGHYSGRN PVPNIQKFIE NMDRDKKTRD AQIMAQQAQS GEVQAHKNKT
PAAPTSSRKT VTDPTTGHQV QIEDVDDHFM DAALNPNLSV PNANLGKPTT MKSDKTQSGE
EYSHAQDVTA PPDPIHPGST SDVPIKGEKT NILFHPTPSV SYEPMFEALE KRTEILCIGV
LVAIVILGKM FGGALYGLIP LGMCVSSGIF LWMKAVVRAG RDQEWSSEQE RGETAVANLI
PESVEWMNTL LGVVWGLIDP DMFASVADTL EDVMQASVPG IIENVRVAEI NQGSNPIRIL
SLRALPDHHV EELKDDIHRQ NSEEKDPQEV AADEEGGDYY NIECSFAYHA KPTGKGVSSK
AKNMHMELVF YLGVKGLFGV PLPIWVELQG LVGTVRLRLQ MSPEPPFLKA LTFTLMGLPK
VQAGCMPMLE SNVNILNLPL ISKFVNYAIG AAAAEYVAPK SMTLDMAKML QGDDIQKDVE
ALGILWIRIH KATGLSKQDR RGSEGGGSDP YITVSFSKYG KPMYCTRVIQ DDLNPVWEET
CALLVTPDLI KADEQLSMEL WDSDRSTADD VVGKVEISMQ KMIQHPGKMY PQVSKLRGTK
AESSMPGELM WEVGYFSKPQ MRPALRTHGK DINLPDNLRE NPALQDAKGS LDSPEEDAVV
HTPPDPLWPS GVCSVIIHQI VNLELENTQG SNGNRKGREF EPARPSGETK EEEGKKLPSS
YCTILYNDEL VYRTRAKVVS SKPIFNAGTE RFMRDWRSGI VTVTVRDQRM REHDPILGVV
PLKLSDILQT SSQVTRWYPL DGGIGFGRVR ISLLFRSVET KLPPNQLGWD VGTFEFRSPK
IIATGYQSAV KLKMRTGGST GRIGRAHCHK LAEGDGVYWD IAKKGGKNNV RLPVKYRYRS
PIVFEFRKPG SRSVDAYAVI WLHHLEDNRE EAINIPIWKT DKGMRLTQNY ITEENFNSIP
DIKIEEIGRL QFRCCFKAGT DEDHARFVSD NDSRETQETW EACHAEGVRT THVSKEMPPA
VQQLHDQSLT QGRDVLSQAD EEDKQKWLSK DGTDWSGAFG EDPSKFVDYK GARSARSDGY
EGQPSAGPGE GGRGDHSSDA YTYDDEDSDD SSDLGLQDAT TTSRDQEGPT ADGEVQTKAD
VKDLHRKQRG LMQWKPMRNL QFAKDETKFA VKKTIGKWKL EGREPGVESE Y
//
