ID A0A094A213_9PEZI Unreviewed; 2140 AA.
AC A0A094A213;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=V492_00783 {ECO:0000313|EMBL:KFY17280.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY17280.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY17280.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY17280.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY17280.1}.
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DR EMBL; JPJU01000143; KFY17280.1; -; Genomic_DNA.
DR STRING; 1420902.A0A094A213; -.
DR HOGENOM; CLU_000443_0_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0034702; C:monoatomic ion channel complex; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0050896; P:response to stimulus; IEA:UniProt.
DR Gene3D; 1.10.287.70; -; 4.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 5.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR45628; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR PANTHER; PTHR45628:SF7; VOLTAGE-DEPENDENT CALCIUM CHANNEL TYPE A SUBUNIT ALPHA-1; 1.
DR Pfam; PF00520; Ion_trans; 4.
DR SMART; SM00054; EFh; 1.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 4.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 367..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 407..431
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..539
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 546..570
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 709..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 776..796
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 808..830
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 842..860
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 905..925
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 937..956
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 977..1001
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1202..1224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1244..1266
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1286..1311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1332..1359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1458..1480
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1538..1559
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1571..1589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1601..1620
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1626..1644
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1656..1681
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1751..1776
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1795..1830
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 1..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1998..2091
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 97..118
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 176..250
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1998..2021
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2051..2087
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2140 AA; 240816 MW; 88633941C79C6FB6 CRC64;
MASNNPSPRH SQSPPQSIPL QNLSRPPDTD AGPSEGEHRG HTRGRSLMTG NAATRGPDVR
YSRLDDSSPS PTLRVLLPSG QHMQPSVEDE LSPGSPVENS HAFQMAVSGL SMPSSNPASP
RDPYGPSYGR EDVGVSPYAP QSYGDVGDGY FNTTTDSDEV GLTDSNYLAP IAGAPNPSTP
RQSSDRDRTS FQSVRFDSPQ TARQSRLGDN LGSSPSGLGG GGRSRSRSFG KSLSPDSRRL
SPSPSNAGPL TRAGSIMRAM SQRVVNFSND AELPEPAYRR KDSTEEMLPN SGLPPIRVTD
EENMEYSPDM QQLPVEKTPS TPVAELPEET VAPPWPITNP LRGNSLRIFA PDNYIRMRLC
EFLVHPWTEP IILILIILQT VLLAVESSKD SYTDPKPRTW SGSPMDFAML ALFAIYTLEI
TAKIIVSGFF FNAEEYSTRT DVNQGLKTTF MSKYMTFFGP RRQQSVRVTR HPDAPPISEA
ISRTFTTAMK TPVAYPTTIE EQQRYQLARR AFFRHSLNRI DIVAVVAFWI SFVIGITGVE
TRKHLYLFKM ISCLRILRLL WLTNGTAIIL KSLKKAAPLL VNVSFLIGFF WLLFAIVGVQ
AFKSSFSRSC TWVDPAGQSN YTNDFQLCGG HLDNASGDPL PWTYENGTSG ARASKGYLCP
RGSLCIEGQS LYNGTVSFDN IVNSLELVFV IMSANTFSDL MYYTTDSDYL AAALFFAAGI
VIMLLWLTNL LIAVITSSFQ VIREESKRSA FTMINTPVAP VEEVKPRSRT TVLKKIYAQT
FWFWILVIIF GFVSQACRSA SMSARRAHFI FVAEIMVTFA LDIEIFFRLA SDFRKFPRSW
KNGFDTLLAI VTTVILLPPI RNSGQPYAWL TVFQIVRIYR VVWAVPITRK LIEKMLGNAT
GILNLVLFVF LITFLISILA VQMFRGDIPA YDSEGETVHT TFFSIWNAFL GLYQILSSEN
WTSILYNVQT FNDHHNTAWM GASFIIGWFI LSFFILINMF IAVIQENFDV SEDEKRLEQV
KAFLQKKDVN SSSSNLSLST IFRFGKTKKA KDPLDYGQTT MEMLLKASVV RDFLDDESGE
PQPGLNTSHT FDNAPEIAPG SLSGLWGRFV TRIWHREPNP FYSSIQFTGA AEGLDPRTMA
REAVSATALR KRAQRDYLNR HPNYNTAMFL FKPDNPVRRF CQRIVGPGRG AERIDGVEPN
KIVWYSFSAF IYAAILTMVV LACVTTPLYQ KEYFETHNFA LRNWFVWTDM AFAAVFSIEA
IIKMIADGCF WTPNAYFRSL WGFIDGWVLI TLWINVITSF LNDGAISRAV GAFKALRALR
LLHISDSARD TFHSVIFVAG WRVLSAIFVS LSLLIPFAIY GVNLFNGQMQ VCNDGGSGII
NLADCSGEYN STPFSGDWPF PAPRVPANPY YDFDNFGSSL FILFQIVSQE GWTDVMWSAQ
SIVGRGLQPR DFASQGNAVF FVVFNLMATV FVLTLFISVF MRTYTEQTGV AFLTAEQRSW
MELRKLLRQV APSKRPSTKS KPKWKDWCYK KAVQKHGFWS RTVTITLVLH LILLMIEYYP
EPFWWTRTRD AVFLFFTLIY MSNVVIRIVG LTWPRFRRSS WDLYSLVSVT GTMITTILLF
GKHDSVTLYQ LHNIFLVSIA LLLIPRNNAL DQLFKTAAAS LTSIGNLLAT WLILFLVYAI
AMTQTFGLTR FGSQGTNNLN FRDVPRALIV LFRMSVGEGW NQIMQDYANT RPPLCVEGTT
FFDSDCGSSS WAYALFISWN ILSMYIFVSL FVSLIYESFS YVYQRSSGHE IVNREETRRF
KQAWSTFDPD GTGYITKEEF PRLLGELSGI FAMRIYDEED TVPRILEEVR AQPMGSRTTS
VATTSGAMGI DLQKLNARIA RIDGKKVRHR RHLYNIFYEE VMVSADPELG ISFTSVLMIL
AHYNIISDNK SLKLDEFLRR RARLQRVEEE VHRRVVIGFF DTMYWARRFR RHLNRHSLSR
ITEISTFPVP EIFVEGDDED ARSVAQSNDP EDPRRSMRAT VDFSDGHASL RDMYGGMGMS
GLHSRDGSVD SRGSRGNLSG LGSGASSPSR SPRLRPHRTN SSVSGAGMDL SDVVPARREG
MHSRSGSTAG EMAVEAFNDS AWGASMRRSY TTRRSGDRRT
//
