ID   A0A094A5X5_9PEZI        Unreviewed;       653 AA.
AC   A0A094A5X5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   RecName: Full=Lysophospholipase {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
DE            EC=3.1.1.5 {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
GN   ORFNames=V491_04754 {ECO:0000313|EMBL:KFY18615.1};
OS   Pseudogymnoascus sp. VKM F-3775.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420901 {ECO:0000313|EMBL:KFY18615.1, ECO:0000313|Proteomes:UP000029338};
RN   [1] {ECO:0000313|EMBL:KFY18615.1, ECO:0000313|Proteomes:UP000029338}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3775 {ECO:0000313|EMBL:KFY18615.1,
RC   ECO:0000313|Proteomes:UP000029338};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid +
CC         H(+) + sn-glycerol 3-phosphocholine; Xref=Rhea:RHEA:15177,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16870,
CC         ChEBI:CHEBI:28868, ChEBI:CHEBI:58168; EC=3.1.1.5;
CC         Evidence={ECO:0000256|RuleBase:RU362103};
CC   -!- SIMILARITY: Belongs to the lysophospholipase family.
CC       {ECO:0000256|ARBA:ARBA00008780, ECO:0000256|RuleBase:RU362103}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY18615.1}.
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DR   EMBL; JPJT01002875; KFY18615.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094A5X5; -.
DR   HOGENOM; CLU_014602_0_0_1; -.
DR   Proteomes; UP000029338; Unassembled WGS sequence.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102545; F:phosphatidyl phospholipase B activity; IEA:UniProtKB-EC.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002642; LysoPLipase_cat_dom.
DR   PANTHER; PTHR10728; CYTOSOLIC PHOSPHOLIPASE A2; 1.
DR   PANTHER; PTHR10728:SF33; LYSOPHOSPHOLIPASE 1-RELATED; 1.
DR   Pfam; PF01735; PLA2_B; 1.
DR   SMART; SM00022; PLAc; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51210; PLA2C; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00555,
KW   ECO:0000256|RuleBase:RU362103};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963, ECO:0000256|PROSITE-
KW   ProRule:PRU00555};
KW   Lipid metabolism {ECO:0000256|PROSITE-ProRule:PRU00555,
KW   ECO:0000256|RuleBase:RU362103};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029338};
KW   Signal {ECO:0000256|RuleBase:RU362103}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|RuleBase:RU362103"
FT   CHAIN           22..653
FT                   /note="Lysophospholipase"
FT                   /evidence="ECO:0000256|RuleBase:RU362103"
FT                   /id="PRO_5005107710"
FT   DOMAIN          61..608
FT                   /note="PLA2c"
FT                   /evidence="ECO:0000259|PROSITE:PS51210"
SQ   SEQUENCE   653 AA;  69957 MW;  55C9A5BAF1A8801B CRC64;
     MKVQFIFTSL ATLSLCNVAL ANIRNLVEEY FSADPACAIS AAEKRAAPDS PSGNYAPAPV
     DCPNTPLTIR EASSLSENET AWLEVRRNNT IEPMSSFLSR ANISGFDAVS YIRGVSNNVS
     NLPNVAIAIS GGGYRALMNG AGFLSAADNR TENSTTVGQI GGLLQSSTYL SGLSGGGWLV
     GSIFANNFTT VVALRDGSAG SSVWEFGNSI LQGPAENGSS ILDKADYYKN IVDEVENKQK
     AGFNASITDY YGRAISYQLV NATDGGPAYT FSSIATEGNF VTGDTPFPIL VADERAPGTS
     VISLNSTVFE FNPFEIGSWD PTTYGFAPTR FVGTNFSAGV VLKNESCIRG FDQIGYVMGT
     SSSLFNQFIL QLNSTGLSGV LLNAAQLALS NFNESENDIA PYQPNPFYHF NNDTNRNAFS
     KQLTLVDGGE DLQNIPLSPL IQPPRAVDVI FAVDASADTT YGWPNGTSLV ATYQRSLNSM
     IENGTSFPTI PDQNTFVNQG FNKRPTFFGC DVKNTTSPAP LIVYLPNAPY TTFSNISTFD
     LSINNTQRNS IIQNGYDVAT MGNGTLDSQW HACVACAVLS RSFTRTDTPV PAACTECFNR
     YCWNGSLDST APSSNYTPTL LLQEASMSSG ASPMLRNFSV MFITAVITVT LLV
//