ID A0A094AAP5_9PEZI Unreviewed; 1293 AA.
AC A0A094AAP5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 35.
DE RecName: Full=Clustered mitochondria protein homolog {ECO:0000256|HAMAP-Rule:MF_03013};
DE AltName: Full=Protein TIF31 homolog {ECO:0000256|HAMAP-Rule:MF_03013};
GN Name=CLU1 {ECO:0000256|HAMAP-Rule:MF_03013};
GN Synonyms=TIF31 {ECO:0000256|HAMAP-Rule:MF_03013};
GN ORFNames=V493_05300 {ECO:0000313|EMBL:KFY24333.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY24333.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY24333.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: mRNA-binding protein involved in proper cytoplasmic
CC distribution of mitochondria. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBUNIT: May associate with the eukaryotic translation initiation
CC factor 3 (eIF-3) complex. {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_03013}.
CC -!- SIMILARITY: Belongs to the CLU family. {ECO:0000256|HAMAP-
CC Rule:MF_03013}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY24333.1}.
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DR EMBL; JPJV01002064; KFY24333.1; -; Genomic_DNA.
DR STRING; 1420906.A0A094AAP5; -.
DR HOGENOM; CLU_003256_2_0_1; -.
DR OrthoDB; 927222at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0007005; P:mitochondrion organization; IEA:UniProtKB-UniRule.
DR GO; GO:0051640; P:organelle localization; IEA:UniProt.
DR CDD; cd15466; CLU-central; 1.
DR Gene3D; 3.30.2280.10; Hypothetical protein (hspc210); 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR HAMAP; MF_03013; CLU; 1.
DR InterPro; IPR033646; CLU-central.
DR InterPro; IPR025697; CLU_dom.
DR InterPro; IPR028275; CLU_N.
DR InterPro; IPR027523; CLU_prot.
DR InterPro; IPR023231; GSKIP_dom_sf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR12601:SF6; CLUSTERED MITOCHONDRIA PROTEIN HOMOLOG; 1.
DR PANTHER; PTHR12601; EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT EIF-3; 1.
DR Pfam; PF13236; CLU; 1.
DR Pfam; PF15044; CLU_N; 1.
DR Pfam; PF12807; eIF3_p135; 1.
DR Pfam; PF13374; TPR_10; 2.
DR Pfam; PF13424; TPR_12; 1.
DR SMART; SM00028; TPR; 3.
DR SUPFAM; SSF103107; Hypothetical protein c14orf129, hspc210; 1.
DR SUPFAM; SSF48452; TPR-like; 2.
DR PROSITE; PS51823; CLU; 1.
DR PROSITE; PS50005; TPR; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_03013};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW RNA-binding {ECO:0000256|HAMAP-Rule:MF_03013};
KW TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339}.
FT DOMAIN 344..588
FT /note="Clu"
FT /evidence="ECO:0000259|PROSITE:PS51823"
FT REPEAT 1014..1047
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 640..669
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1219..1293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1219..1246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1255..1272
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1293 AA; 142707 MW; CF3D0B69D1259431 CRC64;
MAESNDIKGQ SPALAQEAVA EPDNAVTESH ATANGETQEG EEELEQGAET IFSLTVKLPH
KPHKMQIMVS SQEQVHDVRQ SVIELPDTFQ YSCFHLEHNG ERINDFIQLS DVKDLIPESE
LKLVEDPYTE KEARIHVIRV RELIGAAGDR TDTLQGILSG LSLYDSVTES EAPASVEGAP
AAAQTNGAAH PLADYDFQAA GTLSTLLPPT QETHPKTIKM VGLSPWNPPP YHLRQKGHLL
YLQATTLEGE QYQITSHVSG FYVNKSTNAR FDPTPRTAPK SHAAHSLLAL ISDLSPSFEP
AFEKLQEFNN QKEPLTNFQI TNSTPASPWI VPSESSPLTT HQSDLTRSQE SYLISGIENT
ETLRDWNEEF QSTRELPKET AQDRVFRERL TSKLFADYND AAARGAVLVA RGEVAPLNPT
ESRDAQIFVY NNVFFSFGAD GVGTFASEGG DEAARVATGK DVMGVRMVNQ LDIDGLFTPG
TVVIDYLGKR LVGQSIVPGI FKQRDPGENQ IDYGAVDGKE VIAADEKFVP VFEKLSKALK
VKKHAVWDKA GKRHELEGSV ETKGLLGTDG RKYVLDLYRV TPLDIEWMEE NGTAISSPEQ
TGEASYPHRM TVLRPELVEA YWKIKMRAWV NERLEERREA AKADEATKAV TEGEADAESS
EKAKPADSDK DRIDITDFAF SLNPDVFSGQ EPQTEAEIAE WAKDEEEVRL AAKFLRDTVL
PELVRDLKEG DVGFPMDGES LSRLLHKRGI NIRYLGTLAS QAEGRRLEAL KILSIQEMIS
RSFKHIAGNY LRYLPIPFTS ACIAHLLNCL LGTDFNESPV AEIDASLKAL YADTDLSFKD
VTPESLRKEV EAQTLKRYKY TLEENWFAAI KPVQMLREVS LKMGFQLVSK DYYFTKELAA
NAKPAKVAEA PKETANGTAT TTSSKKKKKT RSDSPSGPKS STPAGPPMTF SADDVLNVVP
IIKEASPKSA LAEEALEAGR ISILQGQKKL GQELLLESLS LHEQIYGIMH PEVARVYNTL
SMLYYQLEEK DAAVELARKA VIVSERTLGV DSAETLLSYL NLGLFSHANG ETKLALAYIK
HALQLWKVIY GQNHPDSITT TNNAAVMLQH LKLYHESRLW FEASLDICES VFGKQSINAG
TLLFQLAQAL ALDQDSKASV NRMRESYNIF LTELGAEDKN TKEAESWLEQ LIQNAVSIAK
HAKDVQARRV RAGIKMSPGM SLGQTQAQPG VGQTAGASSG RETRNGMGMD SRSIDELLKF
IEGKEQKKPS SSKKRPGQNN PKRRGGASAG SKA
//
