ID A0A094AB21_9PEZI Unreviewed; 526 AA.
AC A0A094AB21;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE RecName: Full=Beta-xylosidase C-terminal Concanavalin A-like domain-containing protein {ECO:0000259|Pfam:PF17851};
GN ORFNames=V491_03799 {ECO:0000313|EMBL:KFY20335.1};
OS Pseudogymnoascus sp. VKM F-3775.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420901 {ECO:0000313|EMBL:KFY20335.1, ECO:0000313|Proteomes:UP000029338};
RN [1] {ECO:0000313|EMBL:KFY20335.1, ECO:0000313|Proteomes:UP000029338}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3775 {ECO:0000313|EMBL:KFY20335.1,
RC ECO:0000313|Proteomes:UP000029338};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 43 family.
CC {ECO:0000256|ARBA:ARBA00009865, ECO:0000256|RuleBase:RU361187}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY20335.1}.
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DR EMBL; JPJT01002185; KFY20335.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094AB21; -.
DR HOGENOM; CLU_016508_2_0_1; -.
DR Proteomes; UP000029338; Unassembled WGS sequence.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR CDD; cd18617; GH43_XynB-like; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR041542; GH43_C2.
DR InterPro; IPR006710; Glyco_hydro_43.
DR InterPro; IPR023296; Glyco_hydro_beta-prop_sf.
DR PANTHER; PTHR42812; BETA-XYLOSIDASE; 1.
DR PANTHER; PTHR42812:SF12; BETA-XYLOSIDASE-RELATED; 1.
DR Pfam; PF17851; GH43_C2; 1.
DR Pfam; PF04616; Glyco_hydro_43; 1.
DR SUPFAM; SSF75005; Arabinanase/levansucrase/invertase; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361187};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361187};
KW Reference proteome {ECO:0000313|Proteomes:UP000029338}.
FT DOMAIN 324..522
FT /note="Beta-xylosidase C-terminal Concanavalin A-like"
FT /evidence="ECO:0000259|Pfam:PF17851"
FT ACT_SITE 17
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT ACT_SITE 185
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-1"
FT SITE 125
FT /note="Important for catalytic activity, responsible for
FT pKa modulation of the active site Glu and correct
FT orientation of both the proton donor and substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR606710-2"
SQ SEQUENCE 526 AA; 59041 MW; 8A74652F92AFA8E8 CRC64;
MAAITFNNPV ISGFNPDPSV IRIGDDYFLV TSTFEYFPGL PIYHSKDLLN WKLIGHGLTR
SSQLNLRTVE PSGGIWAPTI RYHKGRVYLT TCKWDRYRPK DDERIFPRGF YIFSDNIWDD
NAWSDPLFWD DDDKVYLSTT VRIANRPVGS KLKDFAIHVS EIDLLTGQSL TAPKVIRASP
HGIAEGSHII KRGKYYYLFT AEGGTEAGHQ EWVLRSEVGP LGPWELGPVN PLWYNGTEEE
VQSTGHADVF EDAKGDWWAV FLGVRPRLCE EKWVDSTLGR ETFLVKVVWE NDWPIFNGGK
NITIETEGRH TGQLAPAQLW NADLDRPTLE LGWYQKHTPL KQEWSLSEKP GHLRIYGSCY
PLSSAEAPTL LLRKQTTFQQ RFQAVLNFQP RKAGYEAGIV VWYSLFSYAS IGVTTASEGP
DAGKRVLLLR SPTDKIGVLT ESTYPLGPDG QVTMAIQGDG LQYTLSYNEE GKDDSKALAP
VQSQLLTRSP PIGGAFTGVM FGVYSFGKME PVLDPADFSK ISLESL
//
