ID A0A094AHZ1_9PEZI Unreviewed; 2006 AA.
AC A0A094AHZ1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V493_03823 {ECO:0000313|EMBL:KFY26878.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY26878.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY26878.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY26878.1}.
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DR EMBL; JPJV01001491; KFY26878.1; -; Genomic_DNA.
DR STRING; 1420906.A0A094AHZ1; -.
DR HOGENOM; CLU_000595_0_1_1; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08679; C2_DOCK180_related; 1.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 7..88
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 600..784
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1435..1841
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 93..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 394..486
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1860..2006
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 411..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 472..486
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1866..1880
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1924..1948
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1949..1976
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1988..2006
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2006 AA; 223327 MW; 6FF73BAD0F4A799E CRC64;
MPWQPLPRIA FAVATFPFQA QNAADLPLEL GDELYIIEQG GKNGDWFRGY LIAPPSLLAG
LTSVKGQALE SRVFSGIFPR SCVEVREVLG ESSEEELVES SQLNGYHDES SSKSEGSANS
LNNIAQKLTN GTKTTKKRNS LRDDLRNGTL PPVVRDTNAP KPAAPVPMLN IGDETPTSLS
EPLVDEIASC LREWHSANLH EMLLSRQYPL LDKMTSLVQG LDKSRQQLLH NVLTTHEVEQ
LREKTIWDLV KGNKLVSGEV IVRSPTERGR ILTGEDSAVE ITSLQSMMSC LEENPQHHVE
LVALHHLLVD VKGFVGASTE TTTLVLYLAS RTQQAFPTTL SESFVLEIPP NGSLASLATA
RDMRTLFMDL TSADIGDTNS ADTEVFLVAK VQQNQQPLHG KQPESRAGMV SRENLPSSTG
EKTSLSGSVG KSARRSLMWG KSSQRSANSR NSPVSKMSSV SEKDVGLPPK TSESRTGRTP
PRTATAKVVS RTVGVGALKL NSIMKQDADV EQVMTIWTPS ADFDPDSQTL GEGWDEVIRD
LLESKTGCYE KSAKAERMHL NLRHFASEDG ESLIKATPTL LSNVSRTNKL GFSGAPTKPR
SDIYVTIDKA TLPRGALLSR ATGSATALAT QMTCHNLQVT MEVRRATGDR IENCIYPSSN
GEPVSSWEST VMERGEAWNQ TIRLAVPPQD VPGCHLAIFV SDAPNQPFAI SHLPLWHQQA
FIRDGHHSLL MYKYDETTTH TKPDANGRGG YLGAPWNARG KDDVSKDEAI TGPLSKMRVQ
TYLCSTRFSQ DKVLLGLLNW KDQSVGELSD LLKRLVFVPE IEIVKLLNDV LDSMFAVLVE
HAGNDAFEDL VFNALVTVLG IVHDRRFNLG PLVDHYAETQ FNYPFATPCL VRSFVRLLSD
PTDAESSKRL RATFKVTRHI LKFITHARGQ QIVKEADIGI SNGSPGFSRH LRGIFKALDA
LMRNTSPILV GSQTLAVQHF QGWLPELTGL LTTEEILHIA IDFMDSCSAV KGKLVLYKLI
LIINYAKLDL FSQPDQKAAL TTNTVRWIAP HWGKTAEVTS QWHDQVRLCC SVLSTQIEML
GPEIPDHIPK IIDSYLAIQG APRRPSTRLS LLFPSSYPFP TKPIEGSKPE FDEALVELSA
ILSATSSRPQ GMQLELAEDE MSTLLQDALR VHTSILECEA FPKSWLSIRI YHHRSTMKTL
EYIAKILLES FLPDPEEEAG MDYNTDLWKA FFTTLLKLIG SDALALETFP EQKRRAVWKI
AGDIREQGAE LLRRTWEAIG WETTPEEKQR YGLQKIGGYQ VQYVPGLVGP IVELCLSVHE
GLRRVAVEVL QTMIASEWNL SEDLSTIQME MIDSLDLLFK SKPLTESILQ KFFVNELLDL
FEPLSTMPGD NMYASLSDMI ATIDEFLDLL VAVYSADNAN EASGLIDRLR LMDFLRDMQK
EEIFIRYVHQ LSVVQAESRN FTESGLALRL HADLYDWDPL KILPPLSDPD FPAQSAFERK
ERIYFDMIKH FEDGEAWSSA LVAYKELQVQ YEENVFDFFK LARTQRAIGS VYESIAKSNK
PMLKYFRVAY RGLGFPPGLR DKEFVFEGAP AEKTSAFTDH LQEQYPGAQI VSHLESDDVE
GQFLKVSTLG PYRNLDHAVF QRAKVSNVTR DYLLSAHCQQ FATTVSRNTS GPVEEHFADK
MVYITADQFP TISRRSEIIT AERIRLSPLQ TALERTVRKT QEMTSVERKA AEGDESVVPL
LVEAVSISVS HSSESSIARY RALLPLPAFD EEGEEQVVVL SPLENALKMA LIDHAIMIKR
ILTMFLRSMN PTVRYRQEEL TSREFVVPIF GISDILDFES TFGPELVTLA PVQPRQITPA
PTWSVASPSV PSPPQPRPES PTQRRELGKL NFLNRKAGPP VSFKGGQGRK ESSDEGSSMH
SGVSRGKENR RSFFGRGDNE DWQTDTDGSG LRRSESQGSE GLERPTTATS IGSKVGSVRK
RLSKLTLGRK GSRKEFRAGV VIRETD
//
