ID A0A094AJP5_9PEZI Unreviewed; 590 AA.
AC A0A094AJP5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=V493_05902 {ECO:0000313|EMBL:KFY23355.1};
OS Pseudogymnoascus sp. VKM F-4281 (FW-2241).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420906 {ECO:0000313|EMBL:KFY23355.1, ECO:0000313|Proteomes:UP000029327};
RN [1] {ECO:0000313|EMBL:KFY23355.1, ECO:0000313|Proteomes:UP000029327}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4281 (FW-2241) {ECO:0000313|Proteomes:UP000029327};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY23355.1}.
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DR EMBL; JPJV01002265; KFY23355.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094AJP5; -.
DR STRING; 1420906.A0A094AJP5; -.
DR HOGENOM; CLU_024508_3_2_1; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000029327; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029327};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 546..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 572..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 62743 MW; 1FE6AD27288CC80E CRC64;
MKDYAKIIND RVANSFVGRR FRLEGSGHRY ERKDSRFLTE VRAGMATFFA MAYIISVNSG
ILTDSGGPCE CPAGMTSCDD DPGYQSCLAI INRDFVTGTA AIAALTSVMM GLCANMPIAL
APGMGLNAYF TYTVVGFHGS GPVSYNLALT AVFVEGLVFV GLSLLGLRQW LARSIPSSIK
LASSVGIGLY LTIIGLGYSA GIGLITGAKD TPVELAGCVA SAMVDGICPN STKMRSPTMW
IGIFCGGMLT ALLLMYRVKG AIIAGIALVA ITSWPRNSAV TYFPHTPAGD EMFDFFKQVV
TFHPIQKTLN VLNWNLKGAS GQFGLAFITF LYVDIMDCTG TLYSMAHLAG AIDPVTQDFE
GSAVAYMVDA FGITIGSLFG LSPVTAFIES GAGISEGGKT GITAVVSGLC FFISIFFAPI
FASIPPWATG CTLVIVGSMM CKAAAAINWR YPGDAIPAFV TLAVMPFTYS IAYGLIGGII
TYLIINTSVW IIEKASGGRW VPPGKMHKEP WTYKLVGGVL PPWVVRAAHG KRDFWRPDDE
VVEMTAVRSS DGSAGKGEGS LDATTPDAEM VTDKGEAYRD VETKTHSHAL
//
