ID A0A094AKW7_9PEZI Unreviewed; 1374 AA.
AC A0A094AKW7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=UDP-glucose:glycoprotein glucosyltransferase {ECO:0008006|Google:ProtNLM};
GN ORFNames=V494_08322 {ECO:0000313|EMBL:KFY30019.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY30019.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY30019.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|ARBA:ARBA00004922}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum lumen
CC {ECO:0000256|ARBA:ARBA00004319}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 8 family.
CC {ECO:0000256|ARBA:ARBA00006351}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY30019.1}.
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DR EMBL; JPJW01003371; KFY30019.1; -; Genomic_DNA.
DR STRING; 1420907.A0A094AKW7; -.
DR HOGENOM; CLU_002668_1_0_1; -.
DR OrthoDB; 1734at2759; -.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniPathway.
DR InterPro; IPR040497; Glyco_transf_24.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR009448; UDP-g_GGtrans.
DR InterPro; IPR040693; UGGT_TRXL_1.
DR InterPro; IPR040694; UGGT_TRXL_2.
DR InterPro; IPR040692; UGGT_TRXL_3.
DR InterPro; IPR040525; UGGT_TRXL_4.
DR PANTHER; PTHR11226; UDP-GLUCOSE GLYCOPROTEIN:GLUCOSYLTRANSFERASE; 1.
DR PANTHER; PTHR11226:SF0; UDP-GLUCOSE:GLYCOPROTEIN GLUCOSYLTRANSFERASE; 1.
DR Pfam; PF18404; Glyco_transf_24; 1.
DR Pfam; PF18400; Thioredoxin_12; 1.
DR Pfam; PF18401; Thioredoxin_13; 1.
DR Pfam; PF18402; Thioredoxin_14; 1.
DR Pfam; PF18403; Thioredoxin_15; 1.
DR Pfam; PF06427; UDP-g_GGTase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 42..223
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18400"
FT DOMAIN 270..400
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18401"
FT DOMAIN 406..648
FT /note="UGGT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18402"
FT DOMAIN 661..866
FT /note="UDP-glucose:glycoprotein glucosyltransferase
FT thioredoxin-like"
FT /evidence="ECO:0000259|Pfam:PF18403"
FT DOMAIN 1183..1330
FT /note="Glucosyltransferase 24 catalytic"
FT /evidence="ECO:0000259|Pfam:PF18404"
FT REGION 1332..1374
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1374 AA; 152356 MW; 52265AB85D3C9772 CRC64;
MVRLGNKWSL TGSALAFSCL QSIKVSASPT INVALATSFT SAPYLLELLE TAGDENSTSY
FPLLDRIAEG YFKDAKTDHE LYNSFLKVLR DDGHLDSEGL ASYSLALSLR TSAPRIEAQY
QFYDTAIEQS GDDSSCPVWV LFADKKHCSP ALDDAHGTYN GRRGTEQLQF DRITGNLSAP
ASILYADITS PEFTQFHKKL NQKAQKQEIS YRIRHKKPNV EKSRPLVIGG YGVELALKRT
DYIVIDDREA EAQVQGESVK TEVVLEDEVV ADLKPLSSLE LMSLALKASS FIMQSENPFE
MLTRLSQDFP RYSSAIAAHN ISHGFSNEHA YNRDQMVPSG TNVVWINGLQ VPTRQMDAFS
ILDILRRERK LLNKFSQLGL TGAQTISLLS HKDIAFTKAD DEPARFDWRD EGDGKTIIWL
NNIEKDKRYD GWPASVTTLL QGGYPGQLPQ VRKDLFNLVF PVDLSNLQDV ELVVTQLSDF
VKRALPLRFG LVPLTNSDAA LDQAKIVYYL LDSYGLSTTV AYLNGFYASK GASSSRSANF
EAAIEERKLL KDKIAKSLEE VLDANEADGS IAHSKQWCSR LGANDKVPPV FVNGAAVPRD
ENWMQGMSQR VQMDLRLMAR AVYENTVTDD HWPPMLYLHD AASGRNPFLM PENDKDVQLL
DVNAIYSDHA EAFEGLPTVK IDPSAAQDEW AHMVLVADVE SEHGKQLLKA AVEFSKRNPS
VELVIVPSSE SPAGIASVYD YMAARSFQPL KSGVDLDTLV EAVSISTGGE GSQEKYVQKI
AEKWAAIDDL LTSLSLKTGQ QGLLLNGRLL GPIPTEIELG VSELEQLLGF ERTKRIRPVL
AAVKALGFSE AISDPLASSK LTSLVALSFI SNVPEGIFEQ ASTLRIDSFK VWKSEYTAIE
IGDESTASIH VQVALDPASQ ESQRWIPILK VLSELDGVYL KLFLNPKVVL KDIPIKRFYR
YVLESKPSFN ADGSLKDIKA QFASVPQEAL LTVGMDVPAP WLVAPKQSVT DLDNIKLSSV
NGDVNAVYEL QHILIEGHSS EKETGQAPRG AQLHLGTAAD AHFADTIIMA NLGYFQFKAN
PGFYKINLQE GPSSKIYSID TLGAPGRDAA KPDETTEISL ISFQGLTLFP QLSRNPGQET
EDVLEPTTDL KDDIVSKGFK LAESILGFGK KDTAAAQTTQ AEINIFSVAS GHLYERMLNI
MMVSVMKHTT HTVKFWFISQ FLSPSFKQSL PSLAAAYNFD YEMVTYKWPH WLRSQTEKQR
EIWGYKILFL DVLFPLSLDK VIFVDADQIV RTDMRELVDL DLQGAPYGFT PMCDSRVEME
GFRFWKQGRP TALPRDRRRR QTETAVPPAQ CRSGEPGEPG PGSAESYADA PADL
//
