ID A0A094AXH5_9PEZI Unreviewed; 590 AA.
AC A0A094AXH5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=V494_07050 {ECO:0000313|EMBL:KFY34109.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY34109.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY34109.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY34109.1}.
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DR EMBL; JPJW01002274; KFY34109.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094AXH5; -.
DR STRING; 1420907.A0A094AXH5; -.
DR HOGENOM; CLU_024508_3_2_1; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 547..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 573..590
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 62887 MW; EFB18B99FA4DFBD8 CRC64;
MKDYTKIIND RVARSIIGRR FRLEGSGHRY ERKDSRFLTE VRAGLATFFA MAYIISVNSG
ILTDSGGPCE CPAGMTSCDD DPGYQTCLAI IHRDFVTGTA AIAALTSVMM GVCANMPIAL
APGMGLNAYF TYTVVGFHGS GPVSYNLALT AVFVEGLVFV GLSLLGMRQW LARAIPASIK
LASSVGIGLY LTIIGLGYSA GIGLITGAQD TPVELAGCVA SAMVDGICPN STKMRSPTMW
IGIFCGGMLT AVLLMYRVKG AIIAGIALVA ITSWPRNSAV TYFPHTPAGD EMFDFFKQVV
TFHPIEKTLN VLNWNLKGVS GQFGLAFITF LYVDIMDCTG TLYSMAHLSG AVDPVTQDFE
GSAVAYMVDA FGITIGSLFG LSPVTAFIES GAGISEGGKT GLTAITSGIC FFISIFFAPI
FASIPPWATG CTLVIVGSMM CKAAAAINWR YPGDAIPAFV TLAVMPFTYS IAYGLIGGII
TYIIINTTVW IIEKASGGRL VPPGKIHKEP WTYKLVGGVL PPWVVRAARG KRDFWREDDE
VVEMTTVRSN ESSTGKVDPT LDAATPDMEA SPEKGAPYRD TETTTHGHAL
//
