ID A0A094B4B4_9PEZI Unreviewed; 1028 AA.
AC A0A094B4B4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
DE Flags: Fragment;
GN ORFNames=V494_08222 {ECO:0000313|EMBL:KFY30210.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY30210.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY30210.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the MET18/MMS19 family.
CC {ECO:0000256|ARBA:ARBA00009340}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY30210.1}.
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DR EMBL; JPJW01003330; KFY30210.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094B4B4; -.
DR STRING; 1420907.A0A094B4B4; -.
DR HOGENOM; CLU_003794_0_1_1; -.
DR OrthoDB; 24319at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR040122; Importin_beta.
DR InterPro; IPR041653; Importin_rep_4.
DR InterPro; IPR041389; Importin_rep_6.
DR InterPro; IPR024687; MMS19_C.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR PANTHER; PTHR10527:SF5; IMPORTIN-5 ISOFORM X1; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR Pfam; PF18808; Importin_rep_4; 1.
DR Pfam; PF18829; Importin_rep_6; 1.
DR Pfam; PF12460; MMS19_C; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 31..111
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REPEAT 180..218
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT COILED 799..830
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1028
FT /evidence="ECO:0000313|EMBL:KFY30210.1"
SQ SEQUENCE 1028 AA; 114242 MW; B14B7DC6A8E6B626 CRC64;
MSSVLSPQVH AELTQLLQAL QSGDNSIRSQ AEEHLANNWT NTQPEVLLMG LVEQIHGSTD
TTTRSFASVI FRRIASKTRK SASGEQIELF LSISQEQAYA IREKLLEALG NETVNTVRNK
VGDAVAELAR EYSDNGQQWP ELLGVLFTLS NSKDEGQREN AYRIFATTPG IIEKQHEDTV
LSAFAKGFKD ENVNVRLSAM EAFASFFRTI SKKAQVKYYA LIPEVLNILP PIKESQDSED
LTRALTALID LAEVAPKMFK PLFRNLVAFS ISVIQDKELS DQARQNSLEL MATFADYAPG
MCRKDASFTA DMITQCLSLM TDIGVDDDDA AEWNDSEDME PEESDMNHVA GEHCMDRLAN
RLGGQTILAP TFGWLPRMMT SNAWRDRHAA LMAISAISEG CRDLMVGELD KVLELVVPAL
RDPHPRVRWA GCNALGQMST DFAGTMQENY HQIVLPAIIP VLESAEPRVQ AHAAAALVNF
CEAAQKEVLE PYLDGLLNLL FQILQSPKRY VQEQALSTIA TVADSAEAAF SKYYDTLMPL
LFTVLRQENT KELRLLRAKA MECATLIALA VGKERLRDDA MTLVQLLASI QGSITDADDP
QAQYLMHCWG RMCRVLERDF IPFLPSVMPP LLEIAKAKAD IQLLDDEEQA EAIQQEEGWE
LVPLKGKIIG IKTSTLDEKN IAIELLVVYA QVLEADFAPY VPDIMQNIAV PGLAFFFHDP
VRVISAKLVP QLINSYKKAY GIPSNEVTSL WEPTLEKILE VLTAEPAIET LAEMYHSFYE
SVEVMGKGCL SGKQMDAFIS AAQSALEDYK ERVKERAEEA EENNREEGEE EDDDILYAIE
DDQALLAEMN KAFHCIFKNH GVDFLPAWGR LSATYDAFLK STDPTQRQWG LCIMDDVLEF
CGERSWEYNA FIIDPLAAGC RDPAPANRQA AAYGVGMAAH KGGANWSGFL GAAVGLLFEM
CAVPDARDED NVFVTENACA AIAKILHYNA GQVRSPDETS TRWVETLPVV NDEEAAPYAY
LYLSQLID
//
