ID A0A094BHC5_9PEZI Unreviewed; 1062 AA.
AC A0A094BHC5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Sodium/calcium exchanger membrane region domain-containing protein {ECO:0000259|Pfam:PF01699};
GN ORFNames=V492_05368 {ECO:0000313|EMBL:KFY09742.1};
OS Pseudogymnoascus sp. VKM F-4246.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420902 {ECO:0000313|EMBL:KFY09742.1, ECO:0000313|Proteomes:UP000029299};
RN [1] {ECO:0000313|EMBL:KFY09742.1, ECO:0000313|Proteomes:UP000029299}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4246 {ECO:0000313|EMBL:KFY09742.1,
RC ECO:0000313|Proteomes:UP000029299};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the chromate ion transporter (CHR) (TC 2.A.51)
CC family. {ECO:0000256|ARBA:ARBA00005262}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY09742.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPJU01001857; KFY09742.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094BHC5; -.
DR STRING; 1420902.A0A094BHC5; -.
DR HOGENOM; CLU_289041_0_0_1; -.
DR Proteomes; UP000029299; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015109; F:chromate transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR003370; Chromate_transpt.
DR InterPro; IPR004837; NaCa_Exmemb.
DR PANTHER; PTHR33567; CHROMATE ION TRANSPORTER (EUROFUNG); 1.
DR PANTHER; PTHR33567:SF3; CHROMATE ION TRANSPORTER (EUROFUNG); 1.
DR Pfam; PF02417; Chromate_transp; 2.
DR Pfam; PF01699; Na_Ca_ex; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029299};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 77..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 293..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 474..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 685..705
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 717..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 743..765
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 786..807
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 819..841
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 861..879
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 913..933
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 983..1005
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1017..1034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1040..1060
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 685..830
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 918..1059
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 204..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 245..280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..548
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 564..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..896
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..271
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..894
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1062 AA; 116046 MW; 1F1073DE51716BDE CRC64;
MHINPSKVWD RTTDVVAANW HLGFTAFGGP PVHFQILHKK YVEKYKWVDE QMFQEIFALS
QALPGPASTK MLFCINYLRG GLLAGFGAFL LWCLPGAIGM YGLSLGVSRI GDTLPLPVYA
LLSGLNAATV GIIALAAVQL AQKTITDKVT RALVFLSGVG GMLYTALWFF PVLMAGAGIV
TIVWDFRWLQ RIYKRVWKPR QTLDQTTGEG LEPRQRSSGE MPEDGGAPYA EPDHDERSIY
LRRMPRSEDS NPWSTEIEPS PGSSSDETTR APGESESSDR VVPASLQMNL LTWKTGVCVI
GAFLASFIAI MVIRGLLKSP PRGASLFANL YLAGTIIFGG GPVVIPLLRE YIVAEGWVSP
RDFLLGLALI QSFPGPNFNF AVYLGSLATA GTSLPSFSGA LIGFIGIFTP GIIIVIGVMG
LWSVLRSHRW LLSLLRGINA GAVGLVFTAV YKLWQIGYVD VNNQGGSPLG RDPWWVAITA
TSFVGGAWFG LSAPFAILLG GAMGVAWIKS AARREAWSDP RNPFDRFPGS HFPGSQTAPS
FGGTGNANVL RPLHETRSAN DIRPIQRSSD ILTGPPVFKD DKAKQSPAAD GPDVESVSIH
ASEEGRIRRR FFGIFPRIIS DEDLSTELGL SSRRIRKLKR RAHKRFTVQN QVQSLILSSW
VRILLLLTPI GFGVHYAHFN STTDFLVNFF AVLPLTDMFG QALVEFKMYT ADPRLELIAY
VLCGNINQTF ASAFLLYSDQ VSVLKSTLLG GMLLRILLVT SIAIVTNDSR HRFQRKSIAI
SLSKHLAIAV TGLIIPTALS MVTTPVTSDV SKQSRGVSIV LLILYCLYLY SEWNTYSLLG
LQLSSDKKKQ GEGIIKEKGR MALGVAVIGA VMAAVGRPSP DMPPPPPPPP DEPIDELMDV
TASEEEEGRE PQLHIWISVI TLIVMAVLLA LHILFMSDSV NGISKETGMS KEFIGLILFP
ILGVDSTLLH LDNRYDSEEA TQSTLGLGLQ VILFLTPVLV LVGWARDIKD MNLQFSPFEV
TVLFPAVLVV QASVEENEHG WLSGALLFGT YLTIAIAAWF QD
//
