ID A0A094BKC4_9PEZI Unreviewed; 817 AA.
AC A0A094BKC4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 32.
DE RecName: Full=DNA mismatch repair protein S5 domain-containing protein {ECO:0000259|SMART:SM01340};
GN ORFNames=V494_05593 {ECO:0000313|EMBL:KFY35750.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY35750.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY35750.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY35750.1}.
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DR EMBL; JPJW01001911; KFY35750.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094BKC4; -.
DR STRING; 1420907.A0A094BKC4; -.
DR HOGENOM; CLU_011171_4_0_1; -.
DR OrthoDB; 1369806at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR002099; MutL/Mlh/PMS.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR NCBIfam; TIGR00585; mutl; 1.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF41; MISMATCH REPAIR PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G05820)-RELATED; 1.
DR Pfam; PF01119; DNA_mis_repair; 1.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000029288}.
FT DOMAIN 216..362
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT REGION 466..485
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 817 AA; 88652 MW; 7426D99164133D2B CRC64;
MAIHPLPSST TRILGSCQAL TTPSSLVKEL IDNAIDAKAT SIDVIISANT VDKIEVRDNG
HGIAQEDLNS LGRHGHTSKL RNFEELRAVG SSCLGFRGEA LASAVSLGSV TITTRAEGEP
VAFVVKLKAT GGVSNKSSIS HPIGTTVCVS NFLSAFPVRR QASITDASKT ISKIKNLLQS
YALARLQVRF MLKVSKTGKG NWSYIPHPKD YLKEAAIQVA GKDVAKQCIE IASQCEADAS
MPDAIDENRT AGSFIKILAF LPGPDSDFSK LKGGHYASVD SRPVSCTRGT LKRVMSSYKQ
HIRAFASKTS RESPKDPFIY LRITCPIGSY DPNIEPAKDD VLFEDEYAIL SATEKLFTST
YSIDTIAISG GDIFDVDHDS AIQQSVGISN CVAAADFQTP GASYGTSDNQ GQERITVDAT
VNKASGRELE MLKEVACEPQ SPPSTLERSG QNSLNPWIIA KLNTPVTERG PRGSRTLGKG
PYIPPVDDTP PASFDDLFLT DGVSNRLAGN QISKQPRPGS KQSSVETWIN KQRIYERDGS
AEPQYVPEAQ TPHHPIGRDR LSQPHYEPPV SIGFVSARAL PVGVPWSPPS TQLQSKEKIR
RKSNAPFIPP KRTKVVHTVP ENAFEPSHLT PPGDTLSSPL QGLPTHIPAF DDNVDAAMDF
ERRKVTSTRR LREETAVLAR LENESGGVAL QGLPAQENIV KTVLQDDDPR AYLMRRQKSM
TTYLAGPHQG PKLKRAKTML LPLESISKTL GTHDLVLRMS TETASISRSM QLLTAVDDYS
KSGIRCEGLR MTDSCATEVE KSLNELMAAS QGRLALT
//
