ID   A0A094BXE2_9PEZI        Unreviewed;       826 AA.
AC   A0A094BXE2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=mannan endo-1,4-beta-mannosidase {ECO:0000256|ARBA:ARBA00012706};
DE            EC=3.2.1.78 {ECO:0000256|ARBA:ARBA00012706};
GN   ORFNames=V491_05801 {ECO:0000313|EMBL:KFY15052.1};
OS   Pseudogymnoascus sp. VKM F-3775.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420901 {ECO:0000313|EMBL:KFY15052.1, ECO:0000313|Proteomes:UP000029338};
RN   [1] {ECO:0000313|EMBL:KFY15052.1, ECO:0000313|Proteomes:UP000029338}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3775 {ECO:0000313|EMBL:KFY15052.1,
RC   ECO:0000313|Proteomes:UP000029338};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random hydrolysis of (1->4)-beta-D-mannosidic linkages in
CC         mannans, galactomannans and glucomannans.; EC=3.2.1.78;
CC         Evidence={ECO:0000256|ARBA:ARBA00001678};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC       {ECO:0000256|ARBA:ARBA00005641}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY15052.1}.
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DR   EMBL; JPJT01003614; KFY15052.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094BXE2; -.
DR   HOGENOM; CLU_342928_0_0_1; -.
DR   Proteomes; UP000029338; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0030248; F:cellulose binding; IEA:InterPro.
DR   GO; GO:0016985; F:mannan endo-1,4-beta-mannosidase activity; IEA:UniProt.
DR   GO; GO:0046355; P:mannan catabolic process; IEA:UniProt.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR035971; CBD_sf.
DR   InterPro; IPR000254; Cellulose-bd_dom_fun.
DR   InterPro; IPR001547; Glyco_hydro_5.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR045053; MAN-like.
DR   PANTHER; PTHR31451; MANNAN ENDO-1,4-BETA-MANNOSIDASE 7; 1.
DR   PANTHER; PTHR31451:SF60; MANNAN ENDO-1,4-BETA-MANNOSIDASE 7; 1.
DR   Pfam; PF00734; CBM_1; 1.
DR   Pfam; PF00150; Cellulase; 1.
DR   SMART; SM00236; fCBD; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF57180; Cellulose-binding domain; 1.
DR   PROSITE; PS00562; CBM1_1; 1.
DR   PROSITE; PS51164; CBM1_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029338};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..826
FT                   /note="mannan endo-1,4-beta-mannosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5001893457"
FT   DOMAIN          19..55
FT                   /note="CBM1"
FT                   /evidence="ECO:0000259|PROSITE:PS51164"
SQ   SEQUENCE   826 AA;  90301 MW;  663114141C4DCD05 CRC64;
     MKVKSAASSI FILAGAASAQ QALWAQCGGI NYTGVTTCVS GSYCAYINDW YYQCLPGTAT
     STVATSTSST STLRTSTTTS TSSGSTSTAF AKASGTKFNI DGTTKYYAGT NSYWIGFLTN
     NADVDTVMDD LAASGLKILR VWGFNDVTSV PSSGTVYYQL LSSSGSTINT GTDGLQRLDY
     VVSSAESHGI KLIINFVNNW TDYGGIDAYV SVFGGTHQTW YTNTAAQAQY QKYIAAVVSR
     YKSSSAVFAW ELANESRCNG CDTSVIYNWA ATTSAYIKSL DSDHMVTLGD EGFGLTGDGS
     YPYQYTEGVD FVKNLGISTI DFGTFHLYPS SWGTTNDWGN TWVSTHAAAC VSANKPCYFE
     EYGVTSSRCS VESAWQSTSF GLASSGMGGD SFWQFGDSLS TGNSPDDGYT IFVGTSDWTC
     LVTDHIHETD PSKEWQRNIV TFNTSEVPEE SKKNSPVKLK PATHLTFDGD SSKAGIVSRR
     RETLYVPRGI PEFVGEGYSG RDFQTLSHFA AATSGDLIGG RRIWTQEGIQ LAFTNDFLMH
     AVLMTGASHL KRLNPEIQQD YNILSTKHLH HSLRAFRNAL SSRTYVANNF EAVISTTLLF
     LMQACSNPVF DPANPIIDAM LQHSSGLFDI IRYHPRQAAF TMFQPICTPK LVRAAIPDSG
     PAHGLVQMIE RHALEYGTPD PNAGFYMGVV KSLAPVLDAV ISRPPFGGAP PNALLLYFIH
     WLSFLPPEFV ILVNSYDPKA LIIMAHYYAL VAFILSNWKD GWWWMRDRPE YMIRNIAEFV
     GLESDGSLGQ WSFLNKAHSG DDDAVETEMG ILATVERHAR KIPVEG
//