ID A0A094CIM7_9PEZI Unreviewed; 1682 AA.
AC A0A094CIM7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Clathrin heavy chain {ECO:0000256|PIRNR:PIRNR002290};
GN ORFNames=V496_07351 {ECO:0000313|EMBL:KFY53996.1};
OS Pseudogymnoascus sp. VKM F-4515 (FW-2607).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420909 {ECO:0000313|EMBL:KFY53996.1, ECO:0000313|Proteomes:UP000029302};
RN [1] {ECO:0000313|EMBL:KFY53996.1, ECO:0000313|Proteomes:UP000029302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4515 (FW-2607) {ECO:0000313|Proteomes:UP000029302};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Clathrin is the major protein of the polyhedral coat of
CC coated pits and vesicles. {ECO:0000256|PIRNR:PIRNR002290}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR002290}. Membrane, coated pit
CC {ECO:0000256|PIRNR:PIRNR002290}; Peripheral membrane protein
CC {ECO:0000256|PIRNR:PIRNR002290}; Cytoplasmic side
CC {ECO:0000256|PIRNR:PIRNR002290}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
CC -!- SIMILARITY: Belongs to the clathrin heavy chain family.
CC {ECO:0000256|PIRNR:PIRNR002290}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY53996.1}.
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DR EMBL; JPJY01001398; KFY53996.1; -; Genomic_DNA.
DR STRING; 1420909.A0A094CIM7; -.
DR HOGENOM; CLU_002136_0_0_1; -.
DR OrthoDB; 5474327at2759; -.
DR Proteomes; UP000029302; Unassembled WGS sequence.
DR GO; GO:0030132; C:clathrin coat of coated pit; IEA:InterPro.
DR GO; GO:0030130; C:clathrin coat of trans-Golgi network vesicle; IEA:InterPro.
DR GO; GO:0071439; C:clathrin complex; IEA:InterPro.
DR GO; GO:0032051; F:clathrin light chain binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR Gene3D; 1.25.40.730; -; 1.
DR Gene3D; 2.130.10.110; Clathrin heavy-chain terminal domain; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR016025; Clathrin_H-chain_N.
DR InterPro; IPR022365; Clathrin_H-chain_propeller_rpt.
DR InterPro; IPR016341; Clathrin_heavy_chain.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR10292:SF1; CLATHRIN HEAVY CHAIN; 1.
DR PANTHER; PTHR10292; CLATHRIN HEAVY CHAIN RELATED; 1.
DR Pfam; PF00637; Clathrin; 7.
DR Pfam; PF13838; Clathrin_H_link; 1.
DR Pfam; PF01394; Clathrin_propel; 2.
DR PIRSF; PIRSF002290; Clathrin_H_chain; 1.
DR SMART; SM00299; CLH; 7.
DR SUPFAM; SSF48371; ARM repeat; 6.
DR SUPFAM; SSF50989; Clathrin heavy-chain terminal domain; 1.
DR PROSITE; PS50236; CHCR; 7.
PE 3: Inferred from homology;
KW Coated pit {ECO:0000256|PIRNR:PIRNR002290};
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329,
KW ECO:0000256|PIRNR:PIRNR002290}; Membrane {ECO:0000256|PIRNR:PIRNR002290};
KW Reference proteome {ECO:0000313|Proteomes:UP000029302}.
SQ SEQUENCE 1682 AA; 189999 MW; 4AC9CF38288D875B CRC64;
MAALPIKFTE LLQLTSVGVE PASIGFNTCT LESDSFICVR EKKNEAASPE VVIIDLKQNN
NVTRRPIKAD SAIMHWTKQI IALKAQSRTL QIFDLEQKAK LKSATMNEDV VFWKWFNETT
LGLVTDTAVY HWDVFDQNQA QPVEVFKRHE NLQGSQIINY RVSADGKWMV VIGISQQQGR
VVGAMQLYSK DRGISQALEG HAAAFGTLRL EGAPADTKVF AFAVRTATGA KLHVVEVDHQ
ASNPAFPKKA VDVYFPAEAV NDFPVAMQVS EKYSIIYLVT KYGFIHLYDL ETGTCIFMNR
ISSETIFITA SDSQSEGLVG VNRKGQVLSV AVDEATVIPY LLQNPANSGL AVKLASRAGL
PGADNLYAQQ FDQLISAGNY AEAAKIAANS PRGFLRTPQT IERFKNIPAQ PGQLSIILQY
FGSLLDKGDL NKHETLELVK PVLAQNRKHL IEKWMKESKL DCSEELGDLV RPHDLALALS
IYLRANIPQK VVAAFAELGQ FDKIVPYSSQ VGYQPDYIVL LQHIVRVNPE KGTEFATQLA
NNEGGSLVDV ERVVDIFQSQ NMVQAATAFL LDALKDNKPE QGHLQTRLLE MNLINAPQVA
DAILGNEMFS HYDKARIAQL CEQAGLAQRA LEHYEDPAAI KRVIVNIVAT PTFNQDWLTN
FFGRFSVEQS LDCLDAMMKS NIRQNLQAVV HIATKYSDLL GATKLIDLFE KYKTAEGLFY
YLGSIVNVSE DPDVNFKYIE AATTMQQFNE VERICRDSNH YNPEKVKNFL KEARLTEQLP
LIIVCDRFNF IHDLVLYLYQ NQHFKSIEVY VQRVNPARTP AVIGGLLDVD CDENIIKNLL
STVNAASIPI DELVQEVETR NRLKILLPFL EATLASGNEQ QAVYNALAKI YIDSNNNPEK
FLKDNNQYDT LVVGKYCEKR DPNLAFIAYS KGQNDLELVN ITNENSMFKA QARYLLERAD
EELWNFVLSG NNNHRRSLVD QVISTAVPES KEPEKVSVAV SSFLKNDLPV ELIELLEKIV
LEPSPFSDNG SLQNLLIFTA TKADKSKVMD YIHQLNEYTT TEVADICIEV GLYEEAFEVY
KKINDHPKAV NVLVEHIVSI DRAQEYGERV EIPEVWSRVA KAQLDGLRIS DAVESYIRAQ
DPSNYKEVIE YAVPAGKDED LIKYLKMARK TLREPEIDTA LAFAYARTDQ LSELEDFLKG
TNVADIEESG DKAYAEGYHQ AAKIFFSSIS NWAKLATTLV HLNDYQAAVE CARKANNIKV
WKQVNAACVE KKEFRLAQIC GLNLIVDAEE LQGLVKQYER NGYFDELIAV LEQGLGLERA
HMGMFTELGI ALSKYHPERV MEHLKLFWSR INIPKMIRAC EEANLWPELV FLYCHYDEWD
NAALAMMERA ADAWEHHSFK DIVVKVANLE IYYRALNFYL QEQPSLLTDL LQALTPRIDV
NRVVKMFEKS DNIPLIKPFL LNVQTQNKKA VNNAINDLLI EEEDYKTLRD SVENYDNYDP
VELAQRLERH DLVFFRQIAS NIYRKNKRWE KSIALSKQDK LYKDAIETAA ISGKSEVVEE
LIRYFVDIGS KECYVGMLYS CYDLIPLHIV MELSWRHGLT DFTMPFMINF LAQQSATIET
LKKDNDERKA REQSQVKEEN NTPILGGSRL MLTQGPVAQA TSPGPYGQAN GFAPQPTGFG
GF
//
