ID A0A094CSY4_9PEZI Unreviewed; 2075 AA.
AC A0A094CSY4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KFY50435.1};
GN ORFNames=V496_09344 {ECO:0000313|EMBL:KFY50435.1};
OS Pseudogymnoascus sp. VKM F-4515 (FW-2607).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420909 {ECO:0000313|EMBL:KFY50435.1, ECO:0000313|Proteomes:UP000029302};
RN [1] {ECO:0000313|EMBL:KFY50435.1, ECO:0000313|Proteomes:UP000029302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4515 (FW-2607) {ECO:0000313|Proteomes:UP000029302};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY50435.1}.
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DR EMBL; JPJY01001845; KFY50435.1; -; Genomic_DNA.
DR STRING; 1420909.A0A094CSY4; -.
DR HOGENOM; CLU_000022_6_0_1; -.
DR OrthoDB; 5396558at2759; -.
DR Proteomes; UP000029302; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0009403; P:toxin biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR030918; PT_fungal_PKS.
DR InterPro; IPR032088; SAT.
DR InterPro; IPR001031; Thioesterase.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR04532; PT_fungal_PKS; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF37; FATTY ACID SYNTHASE; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR Pfam; PF16073; SAT; 1.
DR Pfam; PF00975; Thioesterase; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029302};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 364..796
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1663..1737
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1606..1649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1737..1759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1610..1643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1737..1756
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2075 AA; 224973 MW; 967AAFE4BAEB5418 CRC64;
MTGQFQFVVF GDQAIPYHKE LQKLIANKES HTVAVFLAEA YHALKRDISR LSSSQRAQFP
TPSTLAELLV AYQSSPGPNC ALDSALVCLH QIASFISYIS ETQNEYPQSS SSTVIGSCVG
LLAATAASCS QNVVDLLTLG PEIVVVAFRL GLLVQTKTNS VASNSDKSTF YSSVVGGIDK
DSAAHLIDEY CLSKGLSASS RIYVSAVGHG SITVSGPPAH LRDFCSQNSS LKSVNVPVGG
LFHSPHLYSV IDAKNLVETL SVGSQKRVAR LDVLSNSDGQ KIPSTTCKGT LEIALWNILS
KQLRWDLVTE NASSKLAQLG GLSVRILPFA SGSVQSLATA IGQSGSRTVE TTDTAVRLEQ
ESKRSKIAII GFSGRYPEAE SNEEFWNLLV SGLDVHKEIP KDRFDPWLYY DPTGKGKNTS
GVTKGNFLKN PGLFDARFFG LSPREAEQAD PAQRLAMMTA YESMEMAGFV PDATPSSQRD
RVGVFYGTAS DDYRECNASQ NIDTYFVPGG SRAFLPARIN YQWRFSGPSF DVDTACSSSL
AAIHIACNSL WRQDCDTAIA GGTNVLTNPD NWAGLDRAHF LSHTGNCNTF DDGADGYCRA
ESVATVLLKR LEDAEMDGDP IFGTILGAYT NHSAEAVSMT RPHSGAQRAI FSRIMTGAGV
DSSDVSYVEM HGTGTQHGDA CEMDSVLSVF APEGTQRSQS LHLGSTKANI GHAESASGAS
SLIKVLLMME KGWIPPHVGI KTRINRNFPT DFAQRNVHIA LKPTRWTRPL DKPQGRRAFV
NNFGAAGGNS SVLLEDAPLL QPAVQDPRPL HMVAVSAKTP TSLKRNIRAL REYLDVNPDL
SVSSLSFTTT ARRIHHGFRA IVSGASIYDI RNALQVAEAT EGYTSTATVN TTVGFCFTGQ
GPQYLGMGQQ LLQIPQFRTI VMGLEDILRV QGFQSILPIF EGSCTTPLED LPPPTLQLSI
TCLQIALAKF WKSLDITPQV VIGHSLGEYA ALNFAGVLSD SDTIHLVGTR AKLLEKHCTI
GTHAMLAIKA SLSTVASLIA PHPGLEIACI NGPEEIVVAG SNGDIETFSN ALSRVSIKGT
QLKVQFAFHS AQIEPMLEAF QHSCRSVTFK DPAIPVVSPL LSKTITSASE FGLPSVYLSR
HCRETVQFGL ALQASCASGA VTEKLVWVEI GPHPICSNMI KNTVGQDVRA FPSLRRNENP
WKVFVSALTS LHACGIAVNW NEYHSGFKAA LRVLGLPAYQ WELKEYWIPY MHDWCLTKGN
APAQIQQALP SPVEEAPQPI ITASVQRIVE ENHSGNEAWV TARSDVKYPD LLAILNGHRI
NGQPLCPSSA YADMALTLFT RLLEKSSLAD KSDFGVSVCD MAVDKTLLVN GDPSQLIEMK
VSANWSTRTA TFTLCSITEG GKITTNHAKC TGTFTRKSEW TAEWKRRTFL VKSRIDHLQK
SIHDDSESSA HLLKPGMFYK LFSSIVEYDD AFKGLREAII RSEDLECTAK VKFNTLVGEG
DKWVLSPYWI ESLGQITGFT LNGNDALDSA NQVFINHGWG TMKILKALSP EETYRTYIKM
HTEDNSSYAG DLYILDSNEE LIGMYEGVTF NALNRKVFER VLPRPGASSS LKKDSVSRGT
HASSSTSSHA SSVETQEQIT RRAQPSLPMP PAVVQLKKDN LGPDIAASIR AMISDEVGVP
TNELKDEDDL VDLGVDSLLA LTMADRIREE FDVTVDSTAF MGSLTVRDLI QLIARDSASS
SGDDSSGPST PPSTDGLTPA VAVLTPLSGL PTPGIWDCNS NRKMLGHDLA GSTPPDSIKT
PPLPLSAPIL KMVSATSVLL QGNPPMASKT LWLVPDGSGL ATSYLPLPDI DATVAVYGLS
SPFIKRTEGM SQYPFSDLTA TYLTEIRRRQ PHGPYYLGGW SAGGICAYDA AQNLVAVGEE
VKRLILIDSP NPIGLQKLPP RLYDDFDRIG IFGSSGTSAK KPPAWLLPHF TGFVDILHSY
EPQPWVGQKP LETWVVWARD GVADDGSIEI RAGDPPNLKW LLRKRSAEDL GPNGWDKLVG
RENITIEVLE EANHFSMVKS PAANGVSDFI AKAMA
//
