ID A0A094D1R2_9PEZI Unreviewed; 2456 AA.
AC A0A094D1R2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=ethanolamine kinase {ECO:0000256|ARBA:ARBA00038874};
DE EC=2.7.1.82 {ECO:0000256|ARBA:ARBA00038874};
GN ORFNames=V496_07571 {ECO:0000313|EMBL:KFY53465.1};
OS Pseudogymnoascus sp. VKM F-4515 (FW-2607).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420909 {ECO:0000313|EMBL:KFY53465.1, ECO:0000313|Proteomes:UP000029302};
RN [1] {ECO:0000313|EMBL:KFY53465.1, ECO:0000313|Proteomes:UP000029302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4515 (FW-2607) {ECO:0000313|Proteomes:UP000029302};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Phospholipid metabolism; phosphatidylethanolamine
CC biosynthesis; phosphatidylethanolamine from ethanolamine: step 1/3.
CC {ECO:0000256|ARBA:ARBA00037883}.
CC -!- SIMILARITY: Belongs to the choline/ethanolamine kinase family.
CC {ECO:0000256|ARBA:ARBA00038211}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY53465.1}.
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DR EMBL; JPJY01001439; KFY53465.1; -; Genomic_DNA.
DR STRING; 1420909.A0A094D1R2; -.
DR HOGENOM; CLU_000817_0_0_1; -.
DR OrthoDB; 1751631at2759; -.
DR Proteomes; UP000029302; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd05157; ETNK_euk; 1.
DR Gene3D; 3.90.1200.10; -; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR PANTHER; PTHR22603; CHOLINE/ETHANOALAMINE KINASE; 1.
DR PANTHER; PTHR22603:SF66; ETHANOLAMINE KINASE; 1.
DR Pfam; PF01633; Choline_kinase; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029302};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..33
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 112..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 146..169
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..237
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 246..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 373..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..526
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 615..656
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..729
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1327
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1551..1572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1778..1810
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1907..1968
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2436..2456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..282
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 385..400
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 483..508
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..644
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2456 AA; 269579 MW; E2F11E29A26D9F62 CRC64;
MAISDSIQTL SAAFSFGILL QTAISSFIIY FSGHGSTIFQ DRRRLVLITF ILSSALWAQI
GFLNFLIPSG SSNICQGTIA TSTFFDQAAR TLSGAFILWT VAHVSKTPAE KYGLGSLIGA
RAVSGIVFVV FTRPQFAPLC LPRSDALPVS ILVIGLDAII LGLVAARIFT LGLWGNSNRV
QSNKEHGKAL ALFTAGFAIW TGTSVTLHLG LSSIILLLRT VIPATGLGIL LTIATVWSEA
LLSPREAEVG TPESQSPFIA PPRPRFDSTS TGDGSPRSGT RMATNGRLFV VNPSSTPGDS
PQLQSYRDGP QSNFGNIMVN TRSVDIATGA ISTDVPYEIA TFGTSTTIMG GTTTTISAPP
PLIPSIQRSR PIWDGEDPET QQKRSFFSRS KQSAQSGPRK LAISQPILIN AEESSGAPPF
SRIRTVDLAT AAANERVRRE EAATRRLVAT RPAPAPPTGL DPSDALKRSI STVRKKPPGN
YQELKYQKSQ SSVSSNGSSS SSNLSPGLKD VRKRSPRQLN GFDIDEKRQY YKPAIANTLP
SNPKMKEFLS TPEKRQTIMF MKDIVYDDPG LVDSIIKEVP NFSKKPKPPV DRSKSVGLAA
KPSVLHRARP YKKTRDSEGV FFPSEPSPNH RRTRSSSTVL RAPRIGSPTS LPPLPAPPAD
LAQMRGLLKD HIHNMTNDEK VSMLFPMPPV GSFRMHRRSS VPSLPSSVST AEAPEVTSKE
EIASRRSSRR STIISILPVE TKGDLSPKKH TRKLIQRDTY RSTLNASVPD VGNDVVQIRK
SSIQPQKLYS SFTETTDGSD NGDVLRNTDW LHEPLPALSQ RYTIRDSSSS TADSLLKDHK
FMSIMMGYNP TEAPTTRADP TSFLHDSSQT FVTEGFKTPT KTPTADTWHT RIGDEIPAFS
NRQNHSRSKS VPPAPLILRA GKNKKPLAQK PLPVPVIDTP NRALQEIQAQ LKQLEEPDLL
PFIRDRSSSL GDATQDQRDD LLAEMEKEVG EQENRWQQLH ENIDRDSKGS EDFTPWTTRR
NSVASITSSV NTASVKEARK ARVRSIIEAT ENAVVVTGTR NGEIAKPGLW KDKLEEAQKS
YANNAPSFSN SLSTSKIVTA KQASIRAVVA GGCNVVAIPC PNQRTAKPAQ LWKPCSPKAV
VVVGLLWTLP QQPVQIHPCS PEPAALSVRP AQRRTIEPLR FESLHMWHMP TPTRARPTPG
LWRSKNTRPA SIVTRPKTQK PMRKSRPLTF LPDIVESPSP LPHKRETLGI FQFPWGEKSD
QAVYQPASPA ISNLPRLMIP NTLGSNDFNE EYSSSFFDDY DEQDYQSDST SLDADSPSGE
ASDDGFDDST LWEIANLLDS SEVPSRHSLL PQIRIIEDYD DSDDEVAPAG RPAVVRFMPI
MPLSPNPKSP APKSPMDSDP EALALTPLAG TQMQWPVPPS STVEEPEAFI TDIVPKDRSA
WWDGKSHLPS GPRDTVAFKK KQALKASAPL KTMSLLWTPP KAKVAAVSSG LFTLGTFMEV
REVTTHEPAA IAMFSKPRPN TEPLPIISST NLWSDSRRRS VFTFDWISES TVRPPSPSIG
TSSGNSSPGM VTDSDDYSMK TFSTKASSLQ SAIAMEVPFM LVESVPVKET KKTKARSRAS
HAATPEQWNA ALEDAIKAST IPAKKLGATK EMWAHALEEA LQASAQRPVK PVQTPPKKSL
WSTAISLIKP SEKSSSLWSV QKSQGGNKVA RITPVSDPAF KRSSVKISSE LPKLDSTSLW
SVKQPVAATT TVRSWLHEAS PDSQVQLVVT QSLPIMWTPP AQSPSRPTSS SSSKGLWQPR
DPQREQQNPK MVMSITPIIS PAFKKPSAQL SVELPKLTST SLWSATEPVA ATATVRRWLH
ESLPEPPVQP ASAPQVLSTG LWTPPVPAQP KPVSTSKGLW EPCTRTLAQR PTPPTIFDEP
ISAPAPATGR KSTTAGASDL EELPALESSQ LWSRARATSP KEDEVKERDW IRERTTSKVD
FSETSLVVRE ANYRLLDSST VYTALLLVPS VLQIPTLEAR ALDTHDPRPS MVSRKHSTST
VRFVPLTYSP SDSQSSALRL ILSVFPDWEK TDGKIEFVRF TDGITNTLLK AMNVRPGLTP
QEIDDSAVLL RAYGKGTDLI IDRERETQNH ELLMGHGLAP QLLARFNNGM VYRYISGSVT
APGDLRNRDV YTAVAKRLAQ WHAVVPCLPN TRVPVEEVAS EAMEAMVPTE RRDPEVQRKI
DGVAPGKVAP NVWTVTQKWI YALPTATEEQ RARQAELQKE LERTIAELSD RPGLGKNSLV
FAHCDLLSGN VIVEPTAKGE ANGVAAKTPV TTVSFIDYEY AVPSPAAFDI ANHFAEWGGF
DCDFSVLPTR SQRIDFIREY VASYFAHLNV AKTSEELETE AQALFESVDV FRGVPGLYWG
IWAIIQSVIS QIDFDYASYA EVRLGEYYAW RGETEGTREK KGEEMPLRER RWAQEE
//
