ID A0A094DD68_9PEZI Unreviewed; 2536 AA.
AC A0A094DD68;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
GN ORFNames=V497_01766 {ECO:0000313|EMBL:KFY64351.1};
OS Pseudogymnoascus sp. VKM F-4516 (FW-969).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420910 {ECO:0000313|EMBL:KFY64351.1, ECO:0000313|Proteomes:UP000029268};
RN [1] {ECO:0000313|EMBL:KFY64351.1, ECO:0000313|Proteomes:UP000029268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4516 (FW-969) {ECO:0000313|Proteomes:UP000029268};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY64351.1}.
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DR EMBL; JPJZ01000358; KFY64351.1; -; Genomic_DNA.
DR STRING; 1420910.A0A094DD68; -.
DR HOGENOM; CLU_228178_0_0_1; -.
DR OrthoDB; 6206at2759; -.
DR Proteomes; UP000029268; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR CDD; cd02659; peptidase_C19C; 1.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR021905; DUF3517.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR24006:SF953; C-TERMINAL HYDROLASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G08440)-RELATED; 1.
DR PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR Pfam; PF12030; DUF3517; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00973; USP_2; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029268}.
FT DOMAIN 1594..1919
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 26..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2502..2536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2536 AA; 286469 MW; 143FCE3CF514261D CRC64;
MAILHSNKSE AVLWFDQMDP EAIEVSRERA VSSEPCSTRP KPFDDSEYSA RKRQRVSSGS
RSRSADTGKA SSTYVTTPRE HSPSMEARFT TQPHTPSRSQ TNKPIPEPTS SKVTINLRSN
KAVDLTSSPS FSPTTPSKMS NTDQISQLDI ELDSDGAAVP PETVSSSSST LGSPKVELIM
DDEDIEYGQS PPVAVIDDDD DLIFDCDPVL NFPYASGNEP VMVTVRKIAH FFEHDPVDGD
DMFCRLRDWM ASYLQITKNS EVSWSFFGSF LQKSRDSREA VSEFFTQFAE LTARFVAMDV
ITLAKCEELD EQASPPVLVS RPYLLAFGWL LQKRDFNIGQ NLEQHYRFDW GDEVSNMVRH
FIDGVGSIPA LTRFVRGHLA IISKYPKGIE ELTEPSRIVD LAISSSLAYY NNSGPIYRSP
IENTELLIKQ GYQFFKVLAP ALDTIIEKHA TLLTAEAALI HIIGLSRVYL AALNIEDSPV
EESIRHQLQT PPTMPPKQNG IVISAEWKFS MLKKIIVCGQ MQLRVCGVTT MCTELLNLYT
KHKRDDPSRQ PILIHFAEYI MANKLVEYIV GTGSHPELIS ESGNIVGFLM ATKTYTNKET
DTIWQTVTTS QDPRVVEAVL RMLASVLNLL DYDKLLYLCD KASTLPIEAF TPAMRDHCQR
IIGLLIEKAT GDDKIEYLDA PPYDLCVRLI RESSVPRSDA PLGLLDIQHW ATNRLRELVR
HGPESEIRNK IYLASIQDIA SRSPTASGSI CALYGLLSQN IATDLRILTA EHDLTKIMIE
EVEYTNRPQE PNSVSPNFNS PARQARRDLL LAIILHEPRS ITPSLGERLW TAFVGQGAQS
PADREIAWQI LNSAAGKVSS RNVFIATCFE KYLPNLAPEC YTIGSLDFTR EAIQSWLRGV
QGDLLDEDTQ PGSHGLENLW RMILTAPPNS IEDPAINMLV ELYVDSPMIQ SMARPRAHDV
HLRLVNRCLE QMSYAAAKLK ATNNAATSGD YEPMVIATTE QHAGEDELTF TRSLVLLREF
LRAYQLKPYF AVPKPRPTEP GPSTEVKGEL LDFKYQIFEG QEHGPVSGLE VGKSNTVPEL
FAIVEMVTSF KNFKLYHWGA EISDNASTQE VTLEDLQIGK GLVLVARQDD DQPRGGSLKT
RTTSLEVEVI NHFDAFWDYL GMEDRLSKEI YHFLVKFPVY PKLLAAFEDD ATAWTEIFPL
GQPFKCLYAV YALRETLDAR MREGKPDSRI LSRSLGLIVS AITNREVLDS CANEDLRSLL
AQALVECLMQ LLREPIPVET VTECLTPTLL ECLLQILEFA RLSKAAKNSI QMVSSAFEAI
LEASLHSRPF WTSFITASST PELIRKLLLE DHRSSLRKSI MKQMTSKCTF TPSLSALSTL
DVATAFWPLL RDLIPSAVSL PEQCEEAFSV ALLVFRNLAE SSVGSVDIDS SLFQWGSLLT
QHTAQETVGT TDEIDVIARG LSNLLYWCTS FAKASEHPIP SNQLGIQLFN KHLFPPLSDM
EDDDLLPENV PILNSTTRRY LADTIVNLTR DDTEQYREIM NQIESLAPYD ADDDRKYTPL
TSPESSSSNI VPYAFDLPYG FDRSKYLRSS TGYVGLKNLS NTCYLNSLFT QLFMNVSFRG
FMLNVSLSDN IANQKLLAET QKLFGFMQNS FKRFVDPTSL ALSIRTYDDT NIDVNIQMDV
DEFYNLLIDR WESQISSPED KLLFRSFYGG QLVHQVKSKE CPHISESLEP FSAIQCDIKG
KSSLQESLQA YVDGEVMEGD NKYKCSTCDR DVNAVKRACL QDVPDNLIFH LKRFDFNLRT
MQRSKINDYF SFPHKIDMRP YKVEHLMEGE IPSDMFELVG ILVHSGTAES GHYYSYIRER
PSRGKNSAWV EFNDDHVTSF DPNNIEASCF GGLDYRGPEN GSFQFDKSWS AYMLFYQRSS
VVDEHQQELM AATNQRTFQL PISQLFSNFI TRENEMLIRK YCLYDESHAQ FVLRMMDNDK
HFRNGRSPDN HSLSRLALST TLLHLDQVVA RAKDFPDFAT YMLTLCHRLK SCTDCCEDFL
DWLAHHHEAF RHLLMRNPEH MVRSEIALAV VAALSKVKED ATFDYGLGYA SEVEDDVEVV
ESPRLFPKVL LILLRLWDSF HLTVKAWPEY FGLLIRIVGL GTYETAALLD AGFLIKALEI
LTADSALPPH PQYTRMLAII HKRPVTRPVS LENIIGLLEV LLKSCDLSVQ RVRDRENRLA
LADEDTLLPL NEAEYHLLIQ HWTRGNMNIL TEKLLNYNQN PRSTQEVIGL LLENFNDTYL
SVFNAIRHGI RKTPGTASSA PFLVAAMTYC RTVESLESAE KMIYHVSNVT RGIDNSEGRE
FLRFFKDLLG VPSINLSLDQ GAFFRFALDQ IQVWAPSLLT YYDSTVRRET EDYLQSTLFR
HGVHSPADIS AEDQANSQVI ASTVRQLGIA CLRYLHDKHV RPRVEAVKAN IMNILAVIEM
CKPYYDDASE STEEIPFQEF YTSVLLQLKK LTVDELAEDE VSEWENSDDA FSSSEVLDPV
SDICGRSGNE MNDTDV
//
