ID A0A094DD77_9PEZI Unreviewed; 499 AA.
AC A0A094DD77;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=Catalase core domain-containing protein {ECO:0000259|SMART:SM01060};
GN ORFNames=V497_05562 {ECO:0000313|EMBL:KFY57420.1};
OS Pseudogymnoascus sp. VKM F-4516 (FW-969).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420910 {ECO:0000313|EMBL:KFY57420.1, ECO:0000313|Proteomes:UP000029268};
RN [1] {ECO:0000313|EMBL:KFY57420.1, ECO:0000313|Proteomes:UP000029268}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4516 (FW-969) {ECO:0000313|Proteomes:UP000029268};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=heme; Xref=ChEBI:CHEBI:30413;
CC Evidence={ECO:0000256|ARBA:ARBA00001971,
CC ECO:0000256|PIRSR:PIRSR038928-2};
CC -!- SIMILARITY: Belongs to the catalase family.
CC {ECO:0000256|ARBA:ARBA00005329}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY57420.1}.
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DR EMBL; JPJZ01001027; KFY57420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094DD77; -.
DR STRING; 1420910.A0A094DD77; -.
DR HOGENOM; CLU_010645_2_0_1; -.
DR OrthoDB; 3198922at2759; -.
DR Proteomes; UP000029268; Unassembled WGS sequence.
DR GO; GO:0004096; F:catalase activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR CDD; cd08157; catalase_fungal; 1.
DR Gene3D; 2.40.180.10; Catalase core domain; 1.
DR InterPro; IPR018028; Catalase.
DR InterPro; IPR024711; Catalase_clade1/3.
DR InterPro; IPR011614; Catalase_core.
DR InterPro; IPR010582; Catalase_immune_responsive.
DR InterPro; IPR020835; Catalase_sf.
DR PANTHER; PTHR11465; CATALASE; 1.
DR PANTHER; PTHR11465:SF26; CATALASE 2; 1.
DR Pfam; PF00199; Catalase; 1.
DR Pfam; PF06628; Catalase-rel; 1.
DR PIRSF; PIRSF038928; Catalase_clade1-3; 1.
DR PRINTS; PR00067; CATALASE.
DR SMART; SM01060; Catalase; 1.
DR SUPFAM; SSF56634; Heme-dependent catalase-like; 1.
DR PROSITE; PS51402; CATALASE_3; 1.
PE 3: Inferred from homology;
KW Heme {ECO:0000256|ARBA:ARBA00022617, ECO:0000256|PIRSR:PIRSR038928-2};
KW Hydrogen peroxide {ECO:0000256|ARBA:ARBA00023324};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR038928-2};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR038928-2};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Peroxidase {ECO:0000256|ARBA:ARBA00022559};
KW Reference proteome {ECO:0000313|Proteomes:UP000029268}.
FT DOMAIN 9..402
FT /note="Catalase core"
FT /evidence="ECO:0000259|SMART:SM01060"
FT ACT_SITE 64
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT ACT_SITE 137
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-1"
FT BINDING 347
FT /ligand="heme"
FT /ligand_id="ChEBI:CHEBI:30413"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000256|PIRSR:PIRSR038928-2"
SQ SEQUENCE 499 AA; 55799 MW; ECE51B525DA19B56 CRC64;
MSDKTPTYTL AEGCPIASSS TAQTFRSNNT PASSAKSLVL LQDTQLIETL AHFSRERIPE
RVVHARAVGA LGEFEVTKDI SSLTNAKFLN GVGKKSKVVL RVSTVAPQAG AAETQRDVRG
WAMKIFTEEG NQDFVFNSIP VFFVRDPIKF PSVNRSHKKN PATNAADNTM FWDYHNNNQE
GTHAIMILFS NRGLPASIRT LNSYSGHTYK LVNDAGSFTY VKFHFKTNQG IKNLSQAEAD
RLAGEDPDYH THDMFDAINK GDFPTWTLYI QTMTPEEAEK YKVDIFDMTK VWSHKDFPLH
EVGKLTLNEN PRNHFAQIEQ AAFSPSTMVP GIAPTADPML QARMFAYPDA ARYRLGVNYQ
QLPCNAPVSP VYSPYQRDGA SRHDINYGDD PNYVNASLKK VNFKGNRGAN AVSDGGKHDE
WVAGKVQGYT SEVKDEDFEQ PREFWKTLGR SGPNEQRDLV NNICCHLGKA IPRVQKEAVE
TFKKVDAEFA DQVKQGLKL
//
