ID A0A094DL47_9PEZI Unreviewed; 1791 AA.
AC A0A094DL47;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 29.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=V494_05806 {ECO:0000313|EMBL:KFY35562.1};
OS Pseudogymnoascus sp. VKM F-4513 (FW-928).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420907 {ECO:0000313|EMBL:KFY35562.1, ECO:0000313|Proteomes:UP000029288};
RN [1] {ECO:0000313|EMBL:KFY35562.1, ECO:0000313|Proteomes:UP000029288}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4513 (FW-928) {ECO:0000313|Proteomes:UP000029288};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY35562.1}.
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DR EMBL; JPJW01001955; KFY35562.1; -; Genomic_DNA.
DR STRING; 1420907.A0A094DL47; -.
DR HOGENOM; CLU_001112_0_0_1; -.
DR OrthoDB; 25601at2759; -.
DR Proteomes; UP000029288; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd07589; BAR_DNMBP; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR PANTHER; PTHR22834; NUCLEAR FUSION PROTEIN FUS2; 1.
DR PANTHER; PTHR22834:SF20; NUCLEAR FUSION PROTEIN FUS2; 1.
DR Pfam; PF03114; BAR; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029288}.
FT DOMAIN 1060..1285
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 1..253
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 289..367
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..531
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 559..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 804..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 870..1033
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1135..1172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1566..1615
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1632..1716
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..42
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 74..123
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 185..253
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 307..336
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 381..395
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 396..480
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..524
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 606..661
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 828..846
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 876..890
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 909..932
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 934..961
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 986..1002
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1005..1033
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1148..1172
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1581..1615
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1685..1716
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1791 AA; 196181 MW; A5AB48AA59651A55 CRC64;
MDSSITADQN FYAQSNLHQP FQDGNNENTD ISGASPGADS GMTGYTNGAA ADLVDSPDDF
YKGFQGGLDT TKHDAQDGIT TSKPSSGQRI SSTPLLGQNS NGTTAKYPTI AASHTTPKPS
YRSVSAPMND GRAKPAALKG VPRGQQPSVR DLLKRFDPNG EQPSSLPRRT PPRPPAKSPE
VSTRYKPAAS IQKQQPGIRP GQATRDQYGG ASKTPPRITQ RNRFAVEDQR SNNTLSSAAR
SSKAKNQFGE FANTSRSVTN LAISIVPPKP AATDPTRRPL FGEIVPTESG AQIAYGISDP
RSRARRTSDS SLMSQSWSQR QSSSDVDVSP SSPTAWYLGV TPKLDDLGAP KHAKGHNRSQ
SDFTGFPASS VLVGLNEMAF MKSEDKPEER STPKSSTKSR LPISSKRTSH SSASSTPSTR
SSSPFAAKMN SSNKKDQKPT TRPWSPPGHG TSSSRLSARG QGRGPAKIST SASLNAYISS
PPPMKSPPLR SSRPRQPVSA ATTASSRNKV SEASSRSHSS YSNRAESRIQ EKARINRLAS
AGPVDYAAKR ARIQQAFSKT IQETEQKEGD QAPQAATDVK EPKLVLDTNF AGSAAPPKDS
PTLGMPGSFP PQQSEVDESP LSAVSNATAV TLFDNELQTE PAQRHSTDPT PQPLSSQRDS
HGSPEDYFDA NDGSIQIVLD DAINGESQFP DFADSQRQVL DEDHQLQPLT FVDNAVEPET
ESTSFVRASS PHSAFEPGPI ISDLPPQHAA ALSEVDHSIP LEATASITNV QYDTGEFAPP
TLWPSRHSSP SRSSLGLTKL DTLLHEPPTL PHDIGVSPVT EIDYGSSESV GEAEHVDQHD
SHKRASQASW SDMTVDASNR SSWYVNTNRS SGLFQEPSAP PPPPPKEPIL PATYEELFSP
RPDGDDSNDT SSEFYSSMTD LTGINNTIKP PRSRSAIPPI PAPPPWLAGA SSPPPPPKQA
EPAHHTTRRR TPPPSNVWNR HPPPSLHRYS FKDPESRRVS GDEMYSYRPS TSTARSSAQI
SVDGDAGETS LSSTDHLSID VPQQSDESVA PGAATGALRH RKMLIQELID TEAVYLKDMN
VVVEIYQGTA EACPKLGAGD IKAIFRNSDE VIAFSERFLA DIKAASTTIY IPRSTKSKQA
DSAKSGDSIN SGDKERPLSL ADDESDWSKD QKTTIGENFG RHIEEMEKVY ANFLKNSEQG
TNRLQSLQAD PTVNVWLEEC NAVAKDLTGA WDLDALLVKP VQRITRYQLL LTGILKNTPE
LHPDYASLVK SLEDIKRLLD NIDGEKKRIH KVNEIVTGRK RKESDIRSGL KNPFTRRERA
ETAVLHDRAN EDQDYLKSCD KFHSEWIHLQ FIIRDIDLYL ENVTRWVDDF LRYLSAIELV
VRASPSNCPE LESKWARFNL SMRDVGKVAL EEHKSAIREH VLEPFSNLTK AYIPPQAALK
KRNKRRPDFQ RFETLKSQNK KIDEKLAEQV DQYTALNDTL KLELPKLSAL NESLKDICLA
RLITTQVAWY SIWNDKLKTV LEQNELPKDV HDIIDKFNRD FKHQDAKAQA MGILNGTTVA
SARNRLSQST ARDDEVSLKS KSRASTINNR TRGLSTQSEA TTADQSKKSA DQPRASLVAN
SVGLAVVGLG ARPDGRLSVD ESGDRPRPSG ESANSGRRSL FEAPYTPTRW AEGLPPPEPS
FSDAFNSALP WSNANEGSQN DTSRRSSQAP SVSQDPPRAS YNILYVVASL HEFNIEATKT
EAGYPYLTYE DGEIFDVIAE KGELWLAKNQ DDPTETIGWI WNQHFARMVE F
//
