ID A0A094DT98_9PEZI Unreviewed; 689 AA.
AC A0A094DT98;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=RING-type E3 ubiquitin transferase {ECO:0000256|ARBA:ARBA00012483};
DE EC=2.3.2.27 {ECO:0000256|ARBA:ARBA00012483};
GN ORFNames=V496_01614 {ECO:0000313|EMBL:KFY67423.1};
OS Pseudogymnoascus sp. VKM F-4515 (FW-2607).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420909 {ECO:0000313|EMBL:KFY67423.1, ECO:0000313|Proteomes:UP000029302};
RN [1] {ECO:0000313|EMBL:KFY67423.1, ECO:0000313|Proteomes:UP000029302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4515 (FW-2607) {ECO:0000313|Proteomes:UP000029302};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine +
CC [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-
CC cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.;
CC EC=2.3.2.27; Evidence={ECO:0000256|ARBA:ARBA00000900};
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|ARBA:ARBA00004906}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY67423.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JPJY01000233; KFY67423.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094DT98; -.
DR STRING; 1420909.A0A094DT98; -.
DR HOGENOM; CLU_399619_0_0_1; -.
DR OrthoDB; 1830439at2759; -.
DR Proteomes; UP000029302; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR019402; Frag1/DRAM/Sfk1.
DR PANTHER; PTHR22763:SF184; E3 UBIQUITIN-PROTEIN LIGASE HRD1; 1.
DR PANTHER; PTHR22763; RING ZINC FINGER PROTEIN; 1.
DR Pfam; PF10277; Frag1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029302};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786}.
FT TRANSMEM 38..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 435..462
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 540..560
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..592
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 613..634
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 640..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 667..689
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 689 AA; 77703 MW; 217464B15B8DC1E5 CRC64;
MACARFSMVL ALGVTAVAFC ERATLGILYN HLSQRNGGIM ILANVLLLYA LVLILGLQGL
LYGPLSPLES DILFEKLLGT ATEMILAALF LKLKIDGSFV VIFVGMLAGK TWSWIGEGRI
KAHEQEPSAA MQLSSARFPV ALLLSLLFSI YMVFYTIKIM GSSVELAMKR TFSFEFVCLT
ISSTTTITRY ALILIQSYIA GNQRRRTLQD RQGKREPAGE REEFQALLGR QYSRLDDTAE
RINDSVMMLD HDQLDTESPS WYEDCRWYSY LDLIADSTQL TTYLIYLMVS LAFYGPPVHV
IRRLFITALN LLRRVKTLLR HLRAIQHING RSTDATAKEL ESQDICIICL THMKSRLPHA
ASIGPLHRDY QRWMFTKVAA ISASEASKPK RLPCGHRGVD LSIDRPLVAN PPKQLKRRSL
EAAQSGRNVL KGVELIFLAT VVMFIVPYWL LPLISACVWF AMLLGMLMKW LVDGRPKYSS
MSQNQSIAYI SDIGAQTLKP LFVTGSIITT ILFNLSSLCE HWLRHKGHFA RNKERGDKTL
SILSTISAVC GTAGLILLSI FDTVRYPTVH NIFLFLFIGG YLLNAIFICA VYQRLGAHYP
QHRILRISFW IKLAFILTEI ILTIGFLSTM HTAWKDVAAV LEWIIAFIFT LYILSFIIDL
PSKAHDDSVP DDSSILEMVP QERSRPAKE
//
