ID   A0A094EEW7_9PEZI        Unreviewed;      1302 AA.
AC   A0A094EEW7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-NOV-2023, entry version 33.
DE   RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN   ORFNames=V499_03320 {ECO:0000313|EMBL:KFY77226.1};
OS   Pseudogymnoascus sp. VKM F-103.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY77226.1, ECO:0000313|Proteomes:UP000029295};
RN   [1] {ECO:0000313|EMBL:KFY77226.1, ECO:0000313|Proteomes:UP000029295}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY77226.1,
RC   ECO:0000313|Proteomes:UP000029295};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY77226.1}.
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DR   EMBL; JPKB01000521; KFY77226.1; -; Genomic_DNA.
DR   HOGENOM; CLU_003244_1_0_1; -.
DR   Proteomes; UP000029295; Unassembled WGS sequence.
DR   CDD; cd05137; RasGAP_CLA2_BUD2; 1.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR039360; Ras_GTPase.
DR   InterPro; IPR001936; RasGAP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   PANTHER; PTHR10194:SF60; GTPASE-ACTIVATING PROTEIN; 1.
DR   PANTHER; PTHR10194; RAS GTPASE-ACTIVATING PROTEINS; 1.
DR   Pfam; PF00616; RasGAP; 1.
DR   SMART; SM00323; RasGAP; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE   4: Predicted;
FT   DOMAIN          730..964
FT                   /note="Ras-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50018"
FT   REGION          1..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          550..573
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1145..1180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1203..1302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..107
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..129
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..173
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1234..1302
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1302 AA;  144764 MW;  CC3B2BF06D6DB06C CRC64;
     MDKAAQQHDG PAAGSTVPPL APKLGANLIL LQHEQEAGTA SAASEAPPPQ RRKDDSIRVV
     TPEPTHTPAG GTGAGAPDVD VASQASPRSI RGLEKPWERR RGLVFEDAFE TGESGGLQHT
     TSNESDVDDV SNLPRTRPRN RTIDGAQQQR RPSGQLPLRR HRTGSTYSGL GSSDENIPKE
     DPKYLAHPST AFRSAQSQRA DSVKKKPPVA AGRLYRQSNA SSRSGSPIPF PAYVDTLPVP
     IATRDAIKVL KLMNGLNGRM KGEVEYQTSG HGSWAGGVCY IDDKGTFLFE GTESGPNHQT
     IVPDLRGCRV KPPIEENEEN ILDVSIASGM RLRLRPLDTS QYEYWLAALL SWQQNQDGSS
     ASSSEAGELR SVSRRPSFSQ AKDINIIKVG RVYLWDKGTS QAAAGGRQRA DRAWRQVSCI
     LQDNGELKLM TENDVSLLAT IQLSQLSRCG IQELDKTVLN QEYCVAILPQ YTAAATSISI
     VSPVFISLES RVLFEVWYVL LRTFTVPDMY GSQISADGSD DPDSLVIPTP DDLFRIEKTL
     SIRTVEAKLR PTGKKPEQPV DGRRGHKAEP DPSVGDYFAE VVLDGEVRSR TTTKFGTNKP
     FWREESEFGG LPAALPEISI ALKRMKSKPQ PHPQVHGSKS SVSVHTPEIV WEVLCGIVHI
     RMDQLDRGKD VENWWPVLNE KKEAIGEMLI RVRHDELVVL LLKEYKALSD LLHKFTLGLT
     LQMSQYVPSK LRFLAETLLD VFQVSGQAQQ WLVSLVEDEI DGISKETPVQ RLRFSRRMGS
     NDSFDSVSDR EVQLRDMNKS LTGEANLLFR GNSLLTQALD FHMRRLGKEY LEDLLGDKVR
     EINAMNPDCE VDPSRVGASE DLSRNWATLN ALTSDIWAHI SASHNQCPAE LRQILKYVRT
     VAEDRYGNFL RTAPYTSVSG FLFLRFFCPS LLNPKLFGLL RDHPHPRAQR TLTLIAKSLQ
     VLANLSTFGQ KEAWMEPMNR FLAQNRQTVK AFIDNICSIP ADRTRIPPPA SYSTPLAILK
     RLPMTSREGF PSLPYLIDEA RTYAALVRFW LESVAGDTAR VAEFSGDLLA FHNECVALQK
     RADECLRRAE AEAKVEEPPE LKWTDILRSL ERSSALDQRT FTENDIVPHA ANSYPLATPR
     EAARWNRNDD GSIPVPGSAG SETGSRERRE RQTFWESTFG KESLRMPRPL AADVFGGSLD
     IGAMGASPPT ERGLSREGKG GKGFLSGVSG VLRKKGGGEK EREKEQEKQR AKAEKEAVKE
     GEREKEREKE RERKERNKIT RERNGQGEEK GREKEKGKGA AE
//