ID A0A094EF78_9PEZI Unreviewed; 1373 AA.
AC A0A094EF78;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=V498_09374 {ECO:0000313|EMBL:KFY77326.1};
OS Pseudogymnoascus sp. VKM F-4517 (FW-2822).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420911 {ECO:0000313|EMBL:KFY77326.1, ECO:0000313|Proteomes:UP000029270};
RN [1] {ECO:0000313|EMBL:KFY77326.1, ECO:0000313|Proteomes:UP000029270}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4517 (FW-2822) {ECO:0000313|Proteomes:UP000029270};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY77326.1}.
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DR EMBL; JPKA01004081; KFY77326.1; -; Genomic_DNA.
DR HOGENOM; CLU_000445_3_2_1; -.
DR Proteomes; UP000029270; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 5.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd17546; REC_hyHK_CKI1_RcsC-like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 1.20.120.1530; -; 3.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR PANTHER; PTHR45339; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR PANTHER; PTHR45339:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE J; 1.
DR Pfam; PF00672; HAMP; 3.
DR Pfam; PF18947; HAMP_2; 2.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 6.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 2.
DR PROSITE; PS50885; HAMP; 6.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 199..254
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 294..346
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 386..438
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 478..530
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 570..622
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 662..714
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 736..960
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1110..1229
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT REGION 74..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1236..1338
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1351..1373
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 162..207
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 85..105
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1240..1254
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1286..1319
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 1159
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1373 AA; 149155 MW; B69D139616D4A1BC CRC64;
MTDDAALAAA TAYIQSLATS PTGLSALKAS RKDADTNGVE EIHLPGSSTP AKHALERELT
SLAKRVRFLE SNAAAPKDHL VPDTPNDSVD SSPADDSIPT ASTSAAREKI VSTLLASRES
PAGQSTVTYT KLSSEQLEAL REHVDHQSGQ LESQKLELAS VNAQLLRQKQ LQEKALKAVE
VERVNALERE LKKHQQANEA FQKALREIGE IVTAVARGDL SKKVQIHSVE MDPEITTFKR
TINTMMDQLQ VFSSEVSRVA REVGTEGILG GQAQISGVDG TWKELTKNVN VMAQNLTDQV
REIAAVTTAV AHGDLTQKIE RPAQGEILQL QQTINTMVDQ LRTFAAEVTR VARDVGTEGI
LGGQAEIEGV KGMWNTLTVN VNAMANNLTT QVRDIAMVTT AVAKGDLTQK VQAECKGEIF
ELKSTINSMV DQLQQFAREV TKIAREVGTE GRLGGQATVH DVEGTWRDLT ENVNGMAMNL
TTQVREIAKV TTAVAKGDLT EKIGVEVRGE ILDLKITINT MVDKLSIFAF EVSKVAREVG
TDGTLGGQAK VENVEGKWKD LTENVNTMAS NLTSQVRGIS TVTQAIANGD MSQKIEVEAA
GEILVLRETI NNMVDRLSIF SNEIQRVAKD VGVDGKMGGQ ADVAGIGGRW KEITTDVNTM
AMNLTAQVRA FGDITNAATD GDFTKLITVE ASGEMDELKR KINQMVFNLR ESIQRNTAAR
EAAEMANRTK SEFLANMSHE IRTPMNGIIG MTQLTLDTDL TQYQREMLNI VHNLANSLLT
IIDDILDLSK IEANRMVMEE IPYSVRSIVF NALKTLAVKA NEKFLDLTYR VDSSVPDHVV
GDSFRLRQVI LNLVGNAIKF TENGEVSLTI RKADQDNCAG NEYAIEFSVS DTGIGIQNDK
LDLIFDTFQQ ADGSMTRKFG GTGLGLSISK RLVNLMRGDV WVKSTYGKGS SFFFTCTVRL
ATSDISFIEK ALKPYQGHQV LFIDKGETGH GKEISSMLSE IGLEPVVVES DSHSDLMQAG
RPANHPSNYD VVIVDSIETG RRLRSIDEFK YIPIVLLAPV VHVSLKSALD LGITSYMTTP
CQTIDLGNGM IPALENRAMP SLADNTKSFD ILLAEDNVVN QRLAVKILEK YHHVVTVVGN
GLEALEAIKL KRYDCILMDV QMPIMGGFEA TAKIREYEYN IGTTRTPIIA LTAHAMLGDR
EKCIQAQMDE YLSKPLKQNH LIQTILKCAT LGGQLLEKGR EPRQSTKEEK PTKIGPPVKA
PQPLSPLSPA AKKRAEIKSG GKGNIPLENG RSSSSLARTA AVTSMGSPSR ASPSPGSALG
ESRSPAKEGE NPLARVSSVV VPVVPVVAAA ASDRRRRETD AAAEAVAKKR KVG
//
