ID A0A094EVM5_9PEZI Unreviewed; 1983 AA.
AC A0A094EVM5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=F-box domain-containing protein {ECO:0000259|PROSITE:PS50181};
GN ORFNames=V499_04326 {ECO:0000313|EMBL:KFY75700.1};
OS Pseudogymnoascus sp. VKM F-103.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420912 {ECO:0000313|EMBL:KFY75700.1, ECO:0000313|Proteomes:UP000029295};
RN [1] {ECO:0000313|EMBL:KFY75700.1, ECO:0000313|Proteomes:UP000029295}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-103 {ECO:0000313|EMBL:KFY75700.1,
RC ECO:0000313|Proteomes:UP000029295};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY75700.1}.
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DR EMBL; JPKB01000644; KFY75700.1; -; Genomic_DNA.
DR HOGENOM; CLU_235234_0_0_1; -.
DR Proteomes; UP000029295; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR PANTHER; PTHR13018:SF83; CALCIUM PERMEABLE STRESS-GATED CATION CHANNEL 1; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 27..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 109..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 180..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..511
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 532..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 566..587
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..669
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 689..714
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 721..739
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1166..1216
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 292..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 943..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1073..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1145..1168
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1851..1910
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..319
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 980..995
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1868..1890
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1983 AA; 221822 MW; C54F9D62FA994C87 CRC64;
MSISLFSSLE GCQDDDVISP KANEKDIYVQ LVISMGLGVS SFIAFCILRP RWKSLYAARK
RHSDAAMALP DLPDTFFGWI PVLFKVTEEE VLASAGLDAF VFLSFFKMAI KFLGVAFILA
AVIIAPINKH FVGLDLSGGD RKDNETTADA SSSHYVSQGF VYIYAAGKGK HKVEEDESYL
WAYLVFTYVF TGLAIYFLIA ETRKIIKVRQ DYLGSQSTIT DKTIRISGIP EELRSEEKII
EILEKLKIGK VENVTLCRNW KFLDDLMEER AATLRKLEEV VSVHLKRQRA QRNFERASET
PTEYHDDPDQ DENEDRDEGD NLLDNASIEV SLYGQPRPTT RIRGGFWNLS TKKVDAIDYY
EEYLRRLDEK IKDARKKEYT ATPLAFVTMD SIPAAQMAVQ ALIDPTPLQF HASLAPAPSD
IVWSNTYLSR SSRMLRSWSI TIFILILTAI WLIPVASLAS LLNICYIEKF APKLAAVLSR
HDIIRALVQT GLPTLVVSLL NVAVPFLYDF LANYQGSISQ SDVELSVISK NFLFTFFNFF
LVFTVFGTAS KIWPVLQDSL KDSTKIAYNL ATSLQTLGLF YTNFIMLQGI GLFPMRLLEF
GSVSLYPIMR WGAETPRDFA ELDQPPVFKY GFYLPTSLLV FILCVVYSIL PAGFLVLLFG
LIYFVLGYFT YKYQLLYAMD HPQHATGAAW TMISYRIMLG LGIFQLAMAG VIALKQAFTA
ALLVLPLIMF TMWFSYFFAR TFEPLTKYIA LRSIRRDNNE EVNLADEYLG IHRPPGRIRR
RSTIDEDRER DQKFVNPSLV VPLEKMWIHQ RPSAGGETPR TLEHEESTAS SFYYTHTAAD
LASGEANRAT TSHIHLSRGV AKSTPLTNCH LPPAAPPYPV ISDSNPESRD TMVAGRKDLS
AALLASDMQH SVEDDVRIDD SENLSAQRAS QIDMATNVRS CPDELHQQTS PANTDLEHHD
GDGDLSNTLP GSGMLPHPEG KHNVEPKDSW PQRGRALRRT RKVPNPLSRA ESRNRANDAS
IEVNVRFMKK SPTRRGAFYK GRSSSLGELE DIVLEPLAPG QMCASVNEIL ERGGTPVPTT
RKPSVRSTSD QYSIRSKKIP WATRTRKLAA TSDSKPRSHA ETISARGVIQ SIRSGRTLHL
DVERLPSSPQ TRTLSHDEPE GLVEKPSTAS VLPPEILTKI YRRLSPSDFN SARHSCRSWF
ISSLEHSLLE TMLKRSGWFA SIQRELFNNK YLDDHLRMTD EWLMSKHLAK ECALGPDWRG
NGIPSLPTEQ IPTHSKGVAN KTPFRLISKL DFTNMGTHYP GSSSEACGLL FIVSACTKFL
MVARGCMVFV YELNRSHRTG KGADDIESGA IRPITSLICP RRVLGCSMDT SSNRDAIAVL
MDGRMGLVCA ITGNTNRPGP TRTRDLRKMQ EQSNVFPVLR GGSWRQNVSL GTSHSLRSSP
EASNQYLRVS VLAPGQPLAD RYSGRELGER YVGRDYYTST AQRRVRPEPQ TTSSYLMPTE
ASPPTLYTLI CSPDDPPRSI AICPQRCCVA FGCSSGIELH WIDALTGEDL NRWFPLTAPS
DHLYFLPPRT GVDLAKKLRL VSSQGTPRER ISVGERFSGH KRSSVFWAQG GWDANDMFVD
TDIESESRGR IRNGSEHYRA VPLSDGYHLL FIDPNSGVLC LGSDAPFGGP TKLLRKLWFS
GPVGEGSPVA YAAACDLRWG VRVIAAYGLG KEQTICLFSI PIDVFTDGHG RGEQPHIINS
FATISRETAR ENADWMPWWG NDGDRLLQWP TFGYGSRTNT MWPLQVRGQQ VGQCAGLVDV
AIHTGSGVGI TIWAFTRQGV ALTWKLDRGT PHHDHIQRLV VQDGTIREID GNGDIEMCDR
PASRPGSDFD ATPSQQEQFD GTASGLSSEV TRSSRRRRNS SSLEQDAEGQ VLMDSLRNHE
SRVVTQDDRE GDADCLKRRS RFETDHSFEA IAMANDGDGL HYGYRRDLVE QLTGVARIDI
EIR
//
