ID   A0A094EYK6_9PEZI        Unreviewed;       427 AA.
AC   A0A094EYK6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-NOV-2023, entry version 27.
DE   RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
GN   ORFNames=V500_11306 {ECO:0000313|EMBL:KFY81553.1};
OS   Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY81553.1, ECO:0000313|Proteomes:UP000029284};
RN   [1] {ECO:0000313|EMBL:KFY81553.1, ECO:0000313|Proteomes:UP000029284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY81553.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JPKC01003650; KFY81553.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094EYK6; -.
DR   STRING; 1420913.A0A094EYK6; -.
DR   HOGENOM; CLU_008279_10_2_1; -.
DR   Proteomes; UP000029284; Unassembled WGS sequence.
DR   GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR   Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR   InterPro; IPR038765; Papain-like_cys_pep_sf.
DR   InterPro; IPR001394; Peptidase_C19_UCH.
DR   InterPro; IPR018200; USP_CS.
DR   InterPro; IPR028889; USP_dom.
DR   PANTHER; PTHR24006; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR   Pfam; PF00443; UCH; 1.
DR   SUPFAM; SSF54001; Cysteine proteinases; 1.
DR   PROSITE; PS00973; USP_2; 1.
DR   PROSITE; PS50235; USP_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000029284}.
FT   DOMAIN          128..427
FT                   /note="USP"
FT                   /evidence="ECO:0000259|PROSITE:PS50235"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        17..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        51..66
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   427 AA;  47640 MW;  E251ED4955998503 CRC64;
     MATVAIQQPT LPRSPMIRKR TFSSSSDGMH YGPRVSKQPK TARRPLSPQR KRKQPGPEEK
     KKNLDSAFVD GAKVDLAYPF VPPTASKRDK HSAAKEAQAG LEKKCAERHA MAATVSDEWA
     EKVSMRQPGF DNIKMSRCYR HSLLQALLHI PKLVNWLLEF HKLGECCSQR PAVCLACKLR
     DLATLYWVQN SSRQEIYALL KDIDRTLAIR GWATDNPEEY GDPDDQFTAM LEMMSEDMGA
     MGHTRFQAIH STLLTSSIRC SSCGHTTDPH HSAERTLSVP LESGLSGSSL EVFVAAFLRD
     KISGYRCEGC QKSVNVTRDV KIASPADVIS VQLKRAGWNG TVKTKVGITR VLDLTKHAVD
     TSTQLRYELV STVSHQGNSR FGHYIAHAVG PDGKWTEFND ECTRKVSPKA VLMPPGFKPV
     LLYYKRV
//