ID A0A094FFG6_9PEZI Unreviewed; 603 AA.
AC A0A094FFG6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=3-hydroxyacyl-CoA dehydrogenase NAD binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V500_05638 {ECO:0000313|EMBL:KFY89496.1};
OS Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY89496.1, ECO:0000313|Proteomes:UP000029284};
RN [1] {ECO:0000313|EMBL:KFY89496.1, ECO:0000313|Proteomes:UP000029284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY89496.1}.
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DR EMBL; JPKC01001880; KFY89496.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094FFG6; -.
DR STRING; 1420913.A0A094FFG6; -.
DR HOGENOM; CLU_031652_0_0_1; -.
DR Proteomes; UP000029284; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR InterPro; IPR006108; 3HC_DH_C.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR48075:SF3; 3-HYDROXYACYL-COA DEHYDROGENASE; 1.
DR PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR Pfam; PF00725; 3HCDH; 1.
DR Pfam; PF02737; 3HCDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF63825; YWTD domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029284}.
FT DOMAIN 14..184
FT /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT /evidence="ECO:0000259|Pfam:PF02737"
FT DOMAIN 189..282
FT /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00725"
SQ SEQUENCE 603 AA; 64590 MW; B1D2EDD0A8F73212 CRC64;
MSSWTPPTTA GRPVAILGAG VLGRRMALMC IAGGHDVHIR DPSADQLDAA LSYITSTAPS
LTPPDVTPGT ARAFTSLSLA ITNAWLVIEA IPEILSLKTS TFAELAALAP QDCILASNSS
SYKSSAMLSA VPAADRPRIL NMHFFMPPAI RVVELMTCGV THPAIFPFLH SELTKLKMSP
VVVKRESTGF LFNRIWAAIK RECLTVIADG VGTPEDIDGT WTQMFGGAAG PCKLMDQVGL
DTVAHIEEHY IEERGFDPSA RDFVVGEYVD KGKLGNKSQS GGLYPPQPDA PPSAPAQVLY
ILDLGLTNLS APMSSGRVLK GSTDGLTPLT PLSTSESLPD GITTLSTRLY WTCMASPPTN
TGSIRSSTLS GEDITTILPP GAVHTPKQIT ADRTNSYLYV SDREGMRVLR FRPDGSDLTT
LVQTGDFTNP AHKVDQTRWC VGIAVDPIHR LVYWTQKGPS KGSQGRIMRA GLDIPGGETA
SNRSDIEVLF SNLPEPTDLE LDEEAETLYW CDRGELPLGN TVNCASVARG AEKAEAKTEM
EKMLGYKIVV GGLHEAIGLQ LDVKNGVIYA SDLGGSVYRF NFDGSGKEKI YEADCAFAGI
ALV
//
