ID   A0A094FGW5_9PEZI        Unreviewed;       753 AA.
AC   A0A094FGW5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN   ORFNames=V500_05314 {ECO:0000313|EMBL:KFY90069.1};
OS   Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY90069.1, ECO:0000313|Proteomes:UP000029284};
RN   [1] {ECO:0000313|EMBL:KFY90069.1, ECO:0000313|Proteomes:UP000029284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC       transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY90069.1}.
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DR   EMBL; JPKC01001789; KFY90069.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094FGW5; -.
DR   STRING; 1420913.A0A094FGW5; -.
DR   HOGENOM; CLU_001265_46_13_1; -.
DR   Proteomes; UP000029284; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR005828; MFS_sugar_transport-like.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   PANTHER; PTHR24064:SF235; PHOSPHATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G10690)-RELATED; 1.
DR   PANTHER; PTHR24064; SOLUTE CARRIER FAMILY 22 MEMBER; 1.
DR   Pfam; PF00083; Sugar_tr; 2.
DR   SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029284};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        236..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        266..286
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        292..310
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        345..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        379..401
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        514..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        577..599
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        605..623
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          193..627
FT                   /note="Major facilitator superfamily (MFS) profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50850"
FT   REGION          721..753
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        727..742
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   753 AA;  83657 MW;  FB67202C501AFC51 CRC64;
     MGTCLGCGTS TLRRGGTKVL VAVGEGASKM FHRPSPAQES LQPRPPPSKL CITVLLSSPF
     LSILTPALSL ISPPSQRSAE LDIMSNNDGL YHPRVHDPMA GTIPVPHGPD TGTDHATFPY
     DRDAANEKAI FDYLIKPDDS YNSDGVYWAD LPWMKRAAFV SAVDAAEARK ELGAIGTMMK
     ADPLSPIGWY FRNAVLPGAG LGLEGYVLFS IGNLTPLFQA AWGSCWKKYQ VCSENWIAAV
     TYMEILGIIV GQVLVGVLGD WFGRRWGLIQ DALIMFGGLL MLTASWGLDL QGWVICYAIS
     LFFYGIGVGG EYPMTATAAM ENATGAGRVS TKEDRLHRGR KVTMAFLMQG WGQFWNQVVL
     IILMLIFNHS GSPPYSVAMA QWTFRVSFAL PALGTLWLVY YRTYKMPLAS KQLNMAKKKI
     NVTGYDTKSL GLTFTYFGGR LLATTGTWFC NDVFFYGNKL FQSQFISVLS PHGATIMTGW
     TWNLVNVVVS LAGYYCACFL IDNKLFGRKN MMQLGFLMDF ILFVVPAFHY KYYTSIQGVT
     AFQAMYFLSS FFNQFGPNSV TFLIAAEVFP TPVRATAHGL SAAVGKLGAL LASVLYNYID
     TQTKFYVVPW FGLAGMLLTL LFLPDTTGLD LKEQERRWKY IRSGRESEYH GVAVHPKHLS
     LWERLRGAGK YYDPELDYAS KIEDMREDWS EKQEARRQAE VQGGVFDNED DYSQHIHDHF
     VATTPQAESD KIATSTSASD EDALRAANEK RAL
//