ID   A0A094FRJ5_9PEZI        Unreviewed;       433 AA.
AC   A0A094FRJ5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=V500_03695 {ECO:0000313|EMBL:KFY93434.1};
OS   Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY93434.1, ECO:0000313|Proteomes:UP000029284};
RN   [1] {ECO:0000313|EMBL:KFY93434.1, ECO:0000313|Proteomes:UP000029284}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFY93434.1}.
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DR   EMBL; JPKC01001159; KFY93434.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094FRJ5; -.
DR   STRING; 1420913.A0A094FRJ5; -.
DR   HOGENOM; CLU_007383_9_2_1; -.
DR   Proteomes; UP000029284; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05227; AR_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10366:SF564; 3BETA_HSD DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029284}.
FT   DOMAIN          4..261
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   433 AA;  47800 MW;  21E4474AA85E3F7F CRC64;
     MTRVLLTGGS GFIATHVLNV LLKRGHSVVT TVRSQDKADK IRKAHSSFGK DKLDFSIVED
     IAVEGAFDDA VKSDPPFEAV IHTAGPFHFN VTDVQKQLLD PAILGTAGIL KSIKKSAPTV
     KRVVITSSFA AITNPFKGNW PEHTYSEADW NPMTHEQALM NAAFGYTGSK LFAERAAWDF
     VEEEKPNFTL ATLAPPFVFG PVTHNLTSLN ALNTSNQLIN GFVQGSYKDG IPPTMAFIWT
     DVRDLALGHV LAMEKPEAGG KRFFFAAGHF TNKDMVDIIR KNFPEYNDRL PGPQDQGGDY
     PAEGVYKIDN SQTTQVLGIE FTLFEKTIVD TVNSLKTFRA FSSLAIAYSI QSVRAAAMSY
     DVPETTLRRR AHGVTSRRNS TPNLRKLTLY EESALVQYIL DLDSRGFPPR PQAVQEMADL
     LLSKQGKSPT RKN
//