ID A0A094G4C1_9PEZI Unreviewed; 1421 AA.
AC A0A094G4C1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN ORFNames=V500_01895 {ECO:0000313|EMBL:KFY97851.1};
OS Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY97851.1, ECO:0000313|Proteomes:UP000029284};
RN [1] {ECO:0000313|EMBL:KFY97851.1, ECO:0000313|Proteomes:UP000029284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY97851.1}.
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DR EMBL; JPKC01000553; KFY97851.1; -; Genomic_DNA.
DR STRING; 1420913.A0A094G4C1; -.
DR HOGENOM; CLU_004859_0_0_1; -.
DR Proteomes; UP000029284; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd15761; FYVE1_Vac1p_like; 1.
DR CDD; cd15737; FYVE2_Vac1p_like; 1.
DR Gene3D; 4.10.860.20; Rabenosyn, Rab binding domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR006642; Rad18_UBZ4.
DR InterPro; IPR021565; Rbsn_Rab-bd.
DR InterPro; IPR036531; Rbsn_Rab-bd_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR35859:SF5; ION_TRANS DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR35859; NONSELECTIVE CATION CHANNEL PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF11464; Rbsn; 1.
DR SMART; SM00064; FYVE; 2.
DR SMART; SM00734; ZnF_Rad18; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF140125; Rabenosyn-5 Rab-binding domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000029284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT TRANSMEM 1091..1112
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1141..1162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1169..1188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1230..1251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1285..1305
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1317..1335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 341..432
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 43..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1379..1413
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1421 AA; 160312 MW; 02DA643C08660B62 CRC64;
MAARKLGGGR ILGSGKSLAP PNTSSHARSS SLLSIGESVV SADSTVSTPL GTSPLKDSGN
DLGSRVSLDS RNDGNAANTG STKLVCPICN EEMMTLLQLN RHLDDDHREL PPVEQVEVKN
WFEKQVVKAK KFQPLVVINQ KLKGLDVFES NDSLAALPIQ TTSSSIQRTQ QAVEQVRQPD
PDEVVTRTHW QRNGYNDVCT EPSCGKRLGP VNGNINCRKC GRLFCEDHTM YQMKLSRAAQ
HEPVRGFWCR CCETCYKSRE GYNDHSSLIK NHTDAFVALR SQKVDKHHLE ISRLEKRLSK
LTQLLANPPE DVVASGGGLL SGSRNDPRKA IEQSIVTWEE DAKVAKCPFC QQEFGNWTFR
RHHCRICGRV VCADSRTGCS SEIGLNVSRS MHVPFLVADY YNHTEADIDT EIPPGNMNID
IRMCRDCRTT IFSRKDFEAE LVHKPTVQKS YENLLQFERG IRPLLASFQK TLPMLQDPDQ
PPSHTQLAEA AKVRKRLIDS FGKYDMAAKR IRDLPTSNET EAKLQKAIYQ QASNFLHLHM
LPLKSLPKLL KHASPHGSGN PRPARNGGGG ALAAIKYNDI DSASQMSSSS SVLAMEAEEK
ELRERLIVLE EQKFMVSEMI ADANKRRKFD EVSSLSMNME DLSKEIDQIT RGKSWTKKAF
SEWRILSTGL IYLGVRDLLG GEDMRMEVLA HDDDRLINIM SFMDSYREGK SALGNWHDVI
ALAGPALNNR PLYYGRSSSR VCAEAVSANS GRRRRRRTLL FCNNQEQFCG TFCIDRTSSR
KTIVRYSRCV PPGQGSGTVG IDPMSRPRPV VVCIPFTPVM LPSYHEESLA SAIPAEEVTK
VALRLRYLIE QCVPCELEVD LVTKAHSRII THKVIQAAKE AGGTEYGACV VYALLVNKRW
FVRQAMLEIW DAELHEVRAT AAEVIAKQII EGEEDMEYLM SEVMLKRYAT INDGSQTAVA
NVIEKSVDLH ALRVIGSSGY QKTVKYLWKG WLVQDDSDAT TFVDYKQKAN PNYWVHLNPD
RMRAPIYQNA TQVIISLVYL GLYTGAINTV NPTGDLDITE VLLYVFTLGF LCDEFSKFWK
VGRFYLGFWN VFNLILYSLL TVSFVTRCIA LTHPIENDHD GQRERFNELS YNFLAFSAPM
FWGRLLLFMD TFRFFGAMLV VLKVMMKESL IFFALLIVVI IGFLQAFIGM DNVDNKSDAT
IFILQNMANA ILGSPDFSGF DAFAPPFGII LYYIFTFTVM VILLNILIAL YNSAYEDITG
NALDEYMALF AQKTMQYVRA PDENVFIAPF NLIEIFGLIL PLEWWVSKRT YMKLNDYVMA
VIYAPLLIVA AFFEMRSARN VTSNRKRGEE DDDTIEEWEQ LDSSELDLEG EGWTKSVESA
KSNVDLDQAT VEVRELREEL GELKELMKSF LKEKQGQKAE S
//
