ID A0A094G9G6_9PEZI Unreviewed; 2061 AA.
AC A0A094G9G6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=V496_00977 {ECO:0000313|EMBL:KFY68562.1};
OS Pseudogymnoascus sp. VKM F-4515 (FW-2607).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420909 {ECO:0000313|EMBL:KFY68562.1, ECO:0000313|Proteomes:UP000029302};
RN [1] {ECO:0000313|EMBL:KFY68562.1, ECO:0000313|Proteomes:UP000029302}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4515 (FW-2607) {ECO:0000313|Proteomes:UP000029302};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY68562.1}.
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DR EMBL; JPJY01000140; KFY68562.1; -; Genomic_DNA.
DR STRING; 1420909.A0A094G9G6; -.
DR HOGENOM; CLU_001614_0_0_1; -.
DR OrthoDB; 1863779at2759; -.
DR Proteomes; UP000029302; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd06548; GH18_chitinase; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF81383; F-box domain; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000029302}.
FT DOMAIN 1206..1573
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT DOMAIN 1814..1860
FT /note="F-box"
FT /evidence="ECO:0000259|PROSITE:PS50181"
FT REGION 451..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1602..1684
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 451..470
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 480..564
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..601
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..653
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2061 AA; 232828 MW; 8B4F013EF73181F0 CRC64;
MDSCSRICFL YMAFGDELTL QEVGPRLEKN LTMLLPNGST YFGSTWARPK SCLAGVIIRF
PKEEDWQDWV LSAFGRQVKP QTTRKQRRDQ AEELWLTKST ALFEPITRTD LSTAPDWILA
NSKNSFDDVN GWARPFTRYS APVQVPQNPS DSEDFLRDKQ ERIVSLGCNK HCGGGVFGDF
DSLLQTSSKE LSPQRRSARA LEQIQIPCLP LLRSITIYCH IYPILNNLHD PKRKPDLKHT
SAPYPAKTTM AITRFISPRD ARNVNTSSRP QISTVAAKGG GVNQRLQSNL FQDLEVAVSQ
HEKSTEAVLQ ILRKLKSKWS MDEPDFTSNP FEDWILRNVN EEVWQSAITI MYKAKIDESD
IKLKQKVEQI ATSLKIEPNR LFFHIGESVL CSTRGISSLK SLVTLSNNNF DLVLKSIHGA
RQERLTSKEG KASKKSVRED IITVSDITDA MTEKKERKEE TEKLKAQKEK AQVEAQAQVD
AETQREREAA EAQAQADAGE REEEAQRERE AAEARAQADA GEREEEAQRE AAEAQAQADA
GEREEEAQRE GKAAEAQGQT DAEEREEGQE AEPEERAGAQ KDADSQKDTV SQKDQEGADM
QKDTQSQKNG AQQKQTESLR DRELQTVTGT LQETDVQKDI HTQKNGTQQT QTETLREAPK
MVKRKYNERQ SKCGAQSKRL RPCVKVGTTQ WSPQKRLPIT GALREKRRRK GRYEEKRKLY
RQQKRQLSAY PQGIPTQIQF EGLQGLCSAQ KQQDDLFNDE RRHALLRAYH QVCKEDPNTH
LANAGQLAIY IFQYGRPAKV WTAGSEGSQN VGFSADTISI HGKCNCKYDE ADILLLTERE
HAMWAANNND PKIIIIRDHK FLDRRPHQTF QRWFDEMEIE AQVSITPMKI DVQVLNEDTS
TPAVQNMTIQ DAFTLWRDAE ASPEICIQHP PVNFLNIADS GYGCWPGGIT KHYGYLRKIV
SFCESFNHSR EESNVGKPTS LQLSPVDIQK CMGFSIVAQR GAASGWHEDQ NGVTTVLTLE
GNDDNSKAED VVKYWPVFPI NRFRPEEQDA FREDFKEHGE KWRPKLQGAQ IPVIALVCGD
TLIQPPGTIH APITLTNCMF TGAMVWRERD LKQSLTEWLF LAENANCTNE PLPQQTPEIL
QYLLPRVKLE PRKFGYTAEE LPLFEDTCHR LLFLTTEGRG CGCSTACGKR CGCSKKGIPC
GVECHKGLGR DWTCCLPLPA VYDRKFFPKD LPAKDLTHVL YAFANIRPDG EVFLSDEEAD
TKKHFEADSI TNDDGANLYG CLQQLYMLKK KNRYLKVLLS IGGWSYRDNF AVPAATLAGR
SRFASSVVSL VRNLGLDGVD IDWEYPTDNS QAENFVYLLR EVRTALDAYS NSLSEPYPFL
LTVAAPAGPQ QYQTLHLAKM DQYVDFWNLM AYDYSSPKTA THRANLFHDS INPKSTPFNT
NATVDYYVSQ GGIRPKKIVL GIPIYGHAFN HTDGLGHPSI DAVSGTWEAG TYDFKVLPMA
GSEGHIVDKL GASYSYDNTT RELISYDNMY IVLQKANWLK EMDLGGAMWW ESSADAIGDN
SLIRAATVTL KIRSNLDNTL NQLDYPDSIY ANIRARMSDS ETNWTTSSKP VKSNACSTTS
VSTTSDATTF DATPSDATPS DATTSDATTS DATTSDATTS DATLPMLTTS DATSDATTSA
TTTTSSTAAN HRLTIQKWTG LGCTGSMLEN DYIPSEQELN TLNRSPNPYL SFSISRPLRG
REQLDLSTEP GVSSCRKFLH SYWPRDSPGS KQSYLKVASQ LKRPHYYGSQ EQFKDDEEAE
LPLKQQRYSS YNGTITLSQL PVEILLQIMS EIQDRRTLVR LCLVSTVFQG VFNMRKWEFL
RSAFTKEVTQ TQYHIHNITI IISKHIKKHL KGVSMLFEVT WEGLINEGRL DGAVYFVDSL
CHGLDRHDYN MLLQLLRTMY DHVVLETSWD VWAGAFTATN FLINYHSWEA YELRLGAPFQ
SEQSTYNIRE MYDWIEHQSV SRWREIVGQD TLNVNWGNVY FVLTSLQTYG KDEEDELIQA
IITLFKKRTI AKRDGSPNKV L
//
