ID A0A094G9U7_9PEZI Unreviewed; 1539 AA.
AC A0A094G9U7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Rieske domain-containing protein {ECO:0000259|PROSITE:PS51296};
GN ORFNames=V500_01260 {ECO:0000313|EMBL:KFY99776.1};
OS Pseudogymnoascus sp. VKM F-4518 (FW-2643).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420913 {ECO:0000313|EMBL:KFY99776.1, ECO:0000313|Proteomes:UP000029284};
RN [1] {ECO:0000313|EMBL:KFY99776.1, ECO:0000313|Proteomes:UP000029284}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4518 (FW-2643) {ECO:0000313|Proteomes:UP000029284};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- COFACTOR:
CC Name=siroheme; Xref=ChEBI:CHEBI:60052;
CC Evidence={ECO:0000256|ARBA:ARBA00001929};
CC -!- PATHWAY: Nitrogen metabolism; nitrate reduction (assimilation).
CC {ECO:0000256|ARBA:ARBA00005096}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC Nitrate/nitrite porter (TC 2.A.1.8) family.
CC {ECO:0000256|ARBA:ARBA00008432}.
CC -!- SIMILARITY: Belongs to the nitrite and sulfite reductase 4Fe-4S domain
CC family. {ECO:0000256|ARBA:ARBA00010429}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFY99776.1}.
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DR EMBL; JPKC01000364; KFY99776.1; -; Genomic_DNA.
DR STRING; 1420913.A0A094G9U7; -.
DR HOGENOM; CLU_003291_0_1_1; -.
DR UniPathway; UPA00653; -.
DR Proteomes; UP000029284; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0015112; F:nitrate transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IEA:InterPro.
DR GO; GO:0015113; F:nitrite transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-UniPathway.
DR CDD; cd17341; MFS_NRT2_like; 1.
DR CDD; cd19943; NirB_Fer2_BFD-like_1; 1.
DR CDD; cd19944; NirB_Fer2_BFD-like_2; 1.
DR CDD; cd03529; Rieske_NirD; 1.
DR Gene3D; 1.10.10.1100; BFD-like [2Fe-2S]-binding domain; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 2.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR Gene3D; 2.102.10.10; Rieske [2Fe-2S] iron-sulphur domain; 1.
DR Gene3D; 3.30.413.10; Sulfite Reductase Hemoprotein, domain 1; 1.
DR InterPro; IPR007419; BFD-like_2Fe2S-bd_dom.
DR InterPro; IPR041854; BFD-like_2Fe2S-bd_dom_sf.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR023753; FAD/NAD-binding_dom.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005117; NiRdtase/SiRdtase_haem-b_fer.
DR InterPro; IPR036136; Nit/Sulf_reduc_fer-like_dom_sf.
DR InterPro; IPR006067; NO2/SO3_Rdtase_4Fe4S_dom.
DR InterPro; IPR045854; NO2/SO3_Rdtase_4Fe4S_sf.
DR InterPro; IPR006066; NO2/SO3_Rdtase_FeS/sirohaem_BS.
DR InterPro; IPR044772; NO3_transporter.
DR InterPro; IPR004737; NO3_transporter_NarK/NarU-like.
DR InterPro; IPR012748; Rieske-like_NirD.
DR InterPro; IPR017941; Rieske_2Fe-2S.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR NCBIfam; TIGR00886; 2A0108; 1.
DR NCBIfam; TIGR02378; nirD_assim_sml; 1.
DR PANTHER; PTHR43809; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR PANTHER; PTHR43809:SF1; NITRITE REDUCTASE (NADH) LARGE SUBUNIT; 1.
DR Pfam; PF04324; Fer2_BFD; 1.
DR Pfam; PF07690; MFS_1; 1.
DR Pfam; PF01077; NIR_SIR; 1.
DR Pfam; PF03460; NIR_SIR_ferr; 1.
DR Pfam; PF07992; Pyr_redox_2; 1.
DR Pfam; PF13806; Rieske_2; 1.
DR PRINTS; PR00368; FADPNR.
DR PRINTS; PR00397; SIROHAEM.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 2.
DR SUPFAM; SSF50022; ISP domain; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR SUPFAM; SSF56014; Nitrite and sulphite reductase 4Fe-4S domain-like; 1.
DR SUPFAM; SSF55124; Nitrite/Sulfite reductase N-terminal domain-like; 1.
DR PROSITE; PS00365; NIR_SIR; 1.
DR PROSITE; PS51296; RIESKE; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Heme {ECO:0000256|ARBA:ARBA00022617}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nitrate assimilation {ECO:0000256|ARBA:ARBA00023063};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000029284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1143..1162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1169..1189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1241..1261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1351..1371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1391..1413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1425..1443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1449..1468
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1480..1502
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1514..1531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 943..1047
FT /note="Rieske"
FT /evidence="ECO:0000259|PROSITE:PS51296"
SQ SEQUENCE 1539 AA; 168954 MW; 47F4DA042D37E1D8 CRC64;
MHLPSGAGVE SSTLPDIPNS IYNGNGFDIV SDVVHNQGSN GICTPRKKIV IVGLGMVALS
FIEKIIKLDA KNRQYDIVVI GEESHVAYNR VGLTSFFEHR EVEQLYLNPK EWYGSFEDGS
LNYHLNTKVE EVFPDQKTVR TSTGDSVSYD ILVLATGSDA ILPTHTPGYN ANGVFVYRTI
SDLERLMEFA SRHKDTTGVV IGGGLLGLEA AHAMMSLNAF KSSKLIDRNN WVLARQLDAD
AGSLVTDTIR QLGLDVMLRK RVATINTDSS NNVQGIVFED GETLDCSCIC FAIGVTPRDD
LGQKAGIKCT ERGGFIVDAG LRTSIPDIYA IGECASWENQ TFGIIAPGIE MADVLSFNLT
NPEKGPKGFD RPDLSTKLKL LGVNVASFGD FFADRDGPKF LPGRRASKLN GVENGKRSSI
PPTKAPLVKA LTYKDPFSAV YKKYLFTMDG KYLLGGMMIG DTNDYVKLNQ MVKSQKELEV
PPSQFILGTQ NGGEENADDL DDDTQVCSCH NVTKRDVVDK VKEGSCKTIA DVKSCTKAGT
GCGGCMPLIQ SIFNKTMKEM GQEVSNHLCS HIPYSRADLY NIVSVKQLKT FVDIMHAVGK
VPDSLGCELC KPAIGSILAS MYNRHVLDKP VRDLQDTNDK FLANIQRNGT FSVVPRVAGG
EITADRLITI GMVAKKYNLY CKITGGQRID MFGAKKQDLL DIWTELVNAG MESGHAYAKS
LRTVKSCVGT TWCRFGVGDS VGMAIRLEQR YKSIRSPHKI KGGVSGCVRE CAEAQNKDFG
LIATEKGFNV FVGGNGGAKP RHSELLAKDV PPDEVVSLLD RYLIFYIRTA DKLQRTARWI
ENLPGGIDYL REVVINDKLG ICADLERQME ELVSSYFCEW AETIKDPERR KHFEQFSNTP
ETVETVEIIE ERGQQRPTYW PAGSVTEDFK GHEWSHVSWQ PILKSNHFSE ERPQISSASI
KRGDTQISIF KVKGKYYATQ QMCPHKRAFV LSDGLIGDDD AGKYWVSCPL CKRNFELNGE
QAGRCSNDET ANVATFPAEE RGDGWVYLKL PPVEELDALL GTEKWKVKKE EAVDPFEKAD
RVYKSFRGKK VADIKVEIIG KRATAPVGID WQANPQMQDG HLLGRLMVRF FSGPLCDRYG
PRLVFVGILL AGAVPTAMTG LVTNIRGLMA LRFFIGILGA SFVPCQVWTT GYFDKNVIGS
ANALTAGWGN AGGGITYYVM PAVFDSLVHR SGLAPDKAWR VAYIVPFIII VVVALGMLFT
CDDTPSGKWS DRAMPMQGGS SDSSIRGEID TPSSVSIAKD INNIDEKRPQ VISDVESQSD
GTTYLDLAKS EFIVAPTTKE IIQVVISPQT IALFGVYACS FGTELAVNAI LGSYYEKNFP
HLGQTEAGEW AAMFGLLNVL FRPLGGIISD LIYKRTESVW AKKMWLIFLG VAAGAHLIAI
GLLNPKTEAT MFGLFVGLAV FMEAANGANF SLVPHVFPAA NGIVSGTVGA AGNFGGLIFS
IIFRYNGKHY DRSIWIIGVI CIVINMSVFW IRPVPAMRK
//
