ID   A0A094H4Z0_9PEZI        Unreviewed;       351 AA.
AC   A0A094H4Z0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=V502_10932 {ECO:0000313|EMBL:KFZ03451.1};
OS   Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ03451.1, ECO:0000313|Proteomes:UP000029308};
RN   [1] {ECO:0000313|EMBL:KFZ03451.1, ECO:0000313|Proteomes:UP000029308}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. Dihydroflavonol-4-reductase subfamily.
CC       {ECO:0000256|ARBA:ARBA00023445}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFZ03451.1}.
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DR   EMBL; JPKE01004215; KFZ03451.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A094H4Z0; -.
DR   STRING; 1420915.A0A094H4Z0; -.
DR   HOGENOM; CLU_007383_9_2_1; -.
DR   OrthoDB; 1694166at2759; -.
DR   Proteomes; UP000029308; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   CDD; cd05227; AR_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10366; NAD DEPENDENT EPIMERASE/DEHYDRATASE; 1.
DR   PANTHER; PTHR10366:SF242; STEROL-4-ALPHA-CARBOXYLATE 3-DEHYDROGENASE, DECARBOXYLATING; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT   DOMAIN          9..253
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   351 AA;  37052 MW;  8F4997C8179C3339 CRC64;
     MATPSSTTVL VTGGSGFIGS YVILALLSEG YTVRTTIRNL SRSASVLASL TNGGATPASL
     ARLTFAAASL DHDDGWAEAV QGCTYVHHVA SPFPAEPPKH EDDLIIPARE GTLRVLKAAA
     AAGVKRVVLT SSFGAVGYGH APRAEAFTEE DWTVLDGAVK VAPYMKSKTI AEKAAWAFVE
     SGANGGKMEL VTVLPLIVFG PALGKELSAS LLVIKKLMDG SMPGCPNLYF AIVDVRDVAS
     LHLLAMTKPE AANQRFIAAG SDPAASMAQL GQIIKEKRPQ NAKKVPSIQV PNFVVHLLAI
     FDKPVRLILP DLGKISQASN KKAREILGWE PRGTEESIVD TADSLVKYGL V
//