ID A0A094HCQ1_9PEZI Unreviewed; 888 AA.
AC A0A094HCQ1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=V501_07748 {ECO:0000313|EMBL:KFZ06086.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ06086.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ06086.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ06086.1}.
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DR EMBL; JPKD01002220; KFZ06086.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094HCQ1; -.
DR HOGENOM; CLU_012970_0_0_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000801; Esterase-like.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF50; MFS DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF00756; Esterase; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029315};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 81..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 207..224
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 428..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 453..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 491..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 568..586
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 85..591
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 49..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 888 AA; 98109 MW; 8E2F117A47732EC6 CRC64;
MAIMDKSHGI MDVNTPNDTK QPSSIEEGHT LADPTNEKNV TSGSLEKVSD SEAQDDEKPS
EDAQNGVKKI EAVTLAWSKK SLAGVLILIW LVTLVNNFKA TVVGSLTPFA TSDWKSHSLL
TVIDIVASAM TAAVYIPMAK LLDVWGRAEG FLLMLCLCTL GLILMAASKN LPTYCAAQVF
YSVGFGGLAY SWNVIATDVT NLRNRGLAFA FTSSPAVITA FAGSKAAEGF YNNVSWQWGI
GCWAIIFPCV ALPLYWVLNH NLRKAEKQGI ITQEKSGRTL PQQVWYVIKE FDLPGVTLFA
SGLILFLLPF TLAATAPNGW KTGYIIAMIV VGFVLLCLFV LHQTYVAPTP FLKSRFLLDR
TVLGACLLDA TYQISYYCYA SYFSSFLMVV NNLTISEAGY VSNTFSAVAF VFLFITGYII
RVTGRFKFIL WFCLPLYVFA LGLMIHFRQP NGYIGYIVMC EIFFSVSGAI FILCVQLAVL
ATVDHQYVAS VLAFLFVSGT IGGAIGSAVS GAIWTNTFKK ALERHLPESA QPDLQAIYES
LPVQLTYKVG TPERLAIQQA YGYAQTRMLA AGCSVMVLGF IAVAMIRDIN VKKMSQTKDH
LVGISICQSS TSSSGSDKNP AESDNFNCYQ ILPSPWSGEA TSERAERYVV DGNALFLTAT
EAAWRRKASS HFAGGGIIVA IGYPLTGKLY DARRRSLDLT PPTQTPVPGH GGADAFVDFI
DKKVRPAIKA RFPQTTSWRE AIYGHSYGGL FALHVLFTRP QLFDCYIASS PSIWWNTRCI
LHEAKAFLED NTSDDRLPSL MLFYGSFEQN PPQWNDEPLD HYEGRKQVAA DFRMCDNILD
LCEMLRDCTR LHTVSLKPYE GEEHTSVMAC SMSRSLTVFF EEWPLPRK
//
