ID A0A094HK52_9PEZI Unreviewed; 1238 AA.
AC A0A094HK52;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Myosin-1 {ECO:0000256|ARBA:ARBA00016187};
DE AltName: Full=Class I unconventional myosin {ECO:0000256|ARBA:ARBA00032645};
DE AltName: Full=Type I myosin {ECO:0000256|ARBA:ARBA00029665};
GN ORFNames=V501_05860 {ECO:0000313|EMBL:KFZ08656.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ08656.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ08656.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC {ECO:0000256|ARBA:ARBA00004134}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ08656.1}.
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DR EMBL; JPKD01001852; KFZ08656.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094HK52; -.
DR STRING; 1420914.A0A094HK52; -.
DR HOGENOM; CLU_000192_7_6_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0051179; P:localization; IEA:UniProt.
DR CDD; cd01378; MYSc_Myo1; 1.
DR CDD; cd11858; SH3_Myosin-I_fungi; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035535; Fungal_myosin-I_SH3.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR010926; Myosin_TH1.
DR InterPro; IPR036072; MYSc_Myo1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF837; MYOSIN-3-RELATED; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF06017; Myosin_TH1; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00242; MYSc; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS51757; TH1; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00023212};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00782};
KW Reference proteome {ECO:0000313|Proteomes:UP000029315};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 42..716
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 774..965
FT /note="TH1"
FT /evidence="ECO:0000259|PROSITE:PS51757"
FT DOMAIN 1090..1149
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..611
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 955..1002
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1142..1238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1073..1091
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1145..1175
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 135..142
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1238 AA; 136445 MW; 4E14C05C126AAC8D CRC64;
MGISRRPKDK SAGNAPSGGR GAGGGKPNIK KAAFDTTKKK EVGVSDLTLL SKVSNEAINE
NLKKRFENGE IYTYIGHVLV SVNPFRDLGI YTDAVLDSYK GKNRLEMPPH VYAVAESSYY
NMNAYKDNQC VIISGESGAG KTEAAKRIMQ YIANVSGGKD SSIQEIKDMV LATNPLLESF
GNAKTLRNNN SSRFGKYLQL QFNSAGEPVG ADITNYLLEK SRVVGQIMNE RNFHIFYQFT
KGASQKYRET FGVQKPETYV YTSKSKCFDV DGIDDLAEFQ DTLNAMKIIG LSQAEQDEIF
RILAAILWTG NIHFVEDKDG YAAIADQSVV DFLAYLLEVD AAHVVSAITI RILTPRNGEV
IESPANPAQA AATRDGLAKA LYNNLFDWIV ERVNVSLKAR GATSNSIGIL DIYGFEIFEK
NSFEQLCINY VNEKLQQIFI QLTLKTEQEE YAREQIKWTP IQYFDNKIVC DLIEGTRPPG
IFSAMKDATR TAHADPAASD RTFMQSINGM SNPHLTPRQG NFIVKHYAGD VSYTVEGITD
KNKDQLLKGL LNLFAQSQNE FVHTLFPNEV NQDDRRQPPA AGDKIKTSAN ELVATLMKAT
PSYIRTIKPN ENKSFSEYNV PNVMHQIKYL GLQENVRIRR AGFAYRQTYD KFVERFYLLS
PQCSYAGEYT WTGDSKSGAK QILKDTSIPA EEYQFGVTKA FIKAPETLFA LEHMRDRYWH
NMAIRIQRVW RAYLRIRSEA ATRIQRVWRK KRVGAEFLEM RERGHKLLQG RKERRRMSLL
GSRRFMGDYL GCNAGSGPGA RIRNAINIPG NEVILFSCRG EVLESKFGRS SKPSPRIFVL
TKSRFYVVLQ AVVNKQVQIS AERAIPLGSI KFIGLSTSRD DWFSLGIGSP QEADPLLSCV
FKTEFFTHLT RASPGSGSAL LKISDHIAYA KKPGKMTDIK VLRDSQQRED FYKSGAIHTQ
SGEPPNSVSR PLPKGKPIPA KPFTKGRLIR PGGPDGRPSK FANVARSTKP VAHPVAHQSI
AQNPIAHAPV AAHNPLAQQL ASRTRALPQQ PQEISLSQYG ASAAASHAAP APAARAVPPP
PPPPPPAATP AGPIFRAMYD FEGQSANELS FKKDEVVDIV QKENNGWWLA KINGREGWAP
SAYLKEETPP PPPPPSARPS AANGKPKPPA PPAKRPAAGG RKAAALPGQR DSGGMASGNE
GGGSGRSTPS LAGGLAEALR ARQSAMNAGH GGRDEDDW
//
