ID A0A094HXT2_9PEZI Unreviewed; 1085 AA.
AC A0A094HXT2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN ORFNames=V502_03509 {ECO:0000313|EMBL:KFZ19662.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ19662.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ19662.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ19662.1}.
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DR EMBL; JPKE01001393; KFZ19662.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094HXT2; -.
DR STRING; 1420915.A0A094HXT2; -.
DR HOGENOM; CLU_002346_0_0_1; -.
DR OrthoDB; 276651at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR004199; B-gal_small/dom_5.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR032312; LacZ_4.
DR PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR PANTHER; PTHR46323:SF1; LACTASE; 1.
DR Pfam; PF02929; Bgal_small_N; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR Pfam; PF16353; LacZ_4; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SMART; SM01038; Bgal_small_N; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154};
KW Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT DOMAIN 796..1081
FT /note="Beta galactosidase small chain/"
FT /evidence="ECO:0000259|SMART:SM01038"
SQ SEQUENCE 1085 AA; 121206 MW; 60EC21E503994859 CRC64;
MPSLESNFVL STGQGELPDY GNELVFQRNR LPARAYHIPA TSLLLNGTWD FQYATNPLEA
PEPGNFGSRV TSDIESTLEI TALDTPDHSS LDTKSNLQAP NLEWSKINVP GHWQLQGHGR
PQYTNVIYPF PVCPPHVPTE NPTGTYRRTF SVPSAWNETS QLRLRFEGVD SSFHVWVNGH
PVGYHQGSRN PSEFDVTAFV TRDSINEVSV RVYQWCDGTY IEDQDQWWLS GIYRDVYLLA
FPGEARIEDF FVKTILDEQY EDATLAVSLD LALTIDVEVS LTLRDSAQGN QTVKSDTFSV
QADKSKIDLS LHIPAPRKWT AETPTLYGLE ISLRSKALDK TLQTISHNVG FRSVELKDGL
MCVNGSPILL RGVNRHDHHP HHGRAVPLSF IKKDLLLMKQ YNVNALRCSH YPSHPRLYEL
CDELGLWVMD EADLECHGFY DAIARPLNIP EEMDYGERKK LTFPQAAAFT SDNDLWKDQY
VDRMEQVLHR DKNHASVIIW SLGNEAFYGK NHQAMYDYAK RVDPSRLVHY EGDADAQSAD
MFSYMYPSPE TLVQLSKTAG VEGDTFEKPM ILCEYGHAMG NGPGGLEDYQ AVFRDNKRLQ
GGYIWEWANH GLWTGSDSER GGFYAYGGDF GDTPNDDTFV MDGLCFSDHT PTPGLVEFKK
VIEPVRASVS GENLIIENGY DFIDLKHLVA IYKLESFTDS AQIGLSGELP LPNVKPGETA
TVQLPQDILE YKKMSGGWLT VSFRIRASTS WAEAGHEIAW FQHRLAQADS PTAYVPQYPA
SQSSALQLRT SKVEYAVGNS DFDITFCRAR GSVTSWTVGG LPVLALDPET RAAIIPGFWR
SPTDNDRPKD YPYWTHYGLD SLTSQLRDFT IESVDPSTVQ LKIKTYISPP ILGWGFDCTL
TYSISSSGSM RIKVHILPCG PFPAYLPRVG LDVRLAKNLK NASWFGLGPG ESYTDKRSAQ
RVGIWNKTVE ELHTPYEVPQ ENGNRIDTRW VKLASHSGAG VRASRVSEEG VGMLQWAASQ
YSPKMLEKAR HPRDLAVEDG GAVLWRVDVQ GAGVGTGACG PAVAESSMVK CEEVEFDIVL
DGVLA
//
