ID A0A094IBD7_9PEZI Unreviewed; 1827 AA.
AC A0A094IBD7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=chitinase {ECO:0000256|ARBA:ARBA00012729};
DE EC=3.2.1.14 {ECO:0000256|ARBA:ARBA00012729};
GN ORFNames=V502_01134 {ECO:0000313|EMBL:KFZ24377.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ24377.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ24377.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family. Chitinase
CC class V subfamily. {ECO:0000256|ARBA:ARBA00008682}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ24377.1}.
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DR EMBL; JPKE01000438; KFZ24377.1; -; Genomic_DNA.
DR STRING; 1420915.A0A094IBD7; -.
DR HOGENOM; CLU_002846_0_0_1; -.
DR OrthoDB; 1752732at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:UniProtKB-KW.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR CDD; cd00035; ChtBD1; 1.
DR CDD; cd02878; GH18_zymocin_alpha; 1.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 3.10.350.10; LysM domain; 2.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR036861; Endochitinase-like_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR PANTHER; PTHR47700:SF2; CHITINASE; 1.
DR PANTHER; PTHR47700; V CHITINASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_6G13720)-RELATED; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR SUPFAM; SSF57016; Plant lectins/antimicrobial peptides; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
DR PROSITE; PS51782; LYSM; 2.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Chitin-binding {ECO:0000256|ARBA:ARBA00022669};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000029308};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1827
FT /note="chitinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001899919"
FT DOMAIN 325..370
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 389..437
FT /note="LysM"
FT /evidence="ECO:0000259|PROSITE:PS51782"
FT DOMAIN 531..904
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 1228..1248
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1827 AA; 194315 MW; 8C0F75858C9C00CA CRC64;
MRLTLGTAIA KALAAYLALA GHGRAVNSGW ESYLAAHPIS TSTLVPISHV QSPSIESVQA
DVKKPSVTSN TARVRCPEGC NGRKQSNWTL YHDLDRLALC NHTMLLDFAL WNPLNDHGTH
VSIRSCTADF NSSLSMPGRL TNESCRSSKN LVQAEASLQM AWLGSSNVGA AGGIVTAAQQ
MERYISRNEV SCDNTIAFAY SGHAVLGLYA GSGIQSQGIA TTVLRQFAAH VEANGISKSL
LVQLCATNGR SSRFALGIVA NANANLSFVQ ETVKTWSHGK CITKYDKAAA WQNITFLSPS
PPSRTNSTPT VTQLPRGIYP RATCTSIMVD AKDTCGSLAV ECGITAAQFT VYNPSNTLCS
SLAEGQHVCC SSGTLPNFAP KPNSNGTCHS YLVQGRDFCD KIARENSLTV AKLETFNVKT
WGWMGCADLQ AGVNICLSSG SPPMPAPLVN AVCGPQVPGT PIPPAGTDLS TLNGCALNAC
CDIWGQCGTT DKFCTASKGP AGAPGTAATG MNGCISNCGT SIVIGLPPAV FRKIGYFEAF
DSSRPCLNMP VNSFNTTGYT HLHLAFAAIT LDWDVDVTAI HDQFLNFVQM TGFKKILSFG
GWTFSTDPST YFIFRRAMEK SNRGTFVANV VAFVEKYKLD GVDFDWEYPA ETDIEGIPHG
TSMEALNYFL FLNDLRNSLP VGNSLSIAAP ASFWYLKGFP IQAIGLVVDY IIFMTYDLHG
QWDYAHPYSD DGCPGGNCLR SHVNLTETIS ALSMITKAGV PSNKVVVGVT SYGRSFQMTT
AGCTGGDCTY TGPLSGAHGG PCTKTPGYIG NAEIAAIIAG AGTVVAVDGT TLEVTGSVQS
YRDDSFSDIV VYDDTQWIAY MNDDNKATRT AVYAAYNLGG TTDWAVDLQS FAGGSSIVGG
ENGASVVYID PVIFVEPDPE VVGTPPCVLV IPPSTLPTPT TISFAPIGTW IVVGQTIITV
VTPSPITASV ISFYNVPIEA GVTSKNFAVV SSLKPEPLVV SAGGTATTIT FPAGPTVLSG
PQVVIANHIT YSVIGGSVII TSAGSEVGAL SVGVPPAKNT PQTLTLPNGV VFTVPATTPS
TFYSLPTTVY ESNGVTQTFS QAQFTDLATI NAQTTVTTVL TEVGYGSSST ATSTTPVAFW
VGVGGFYWSP VPLPTPPPIG IPPIRIPSLP SFPKIPSFPC FKLFDIFSID CPPDKSQPRT
KFRSGHPSST CKSGCGTLCT ADCNLQDHST SSESSSSTST SSSSSSTSFD LCSQGCVTCD
ASAAKATMVP SKRELEGRSL IAPEHYKGGV DEFMDVETDL ATYPVFHGIY PDISTGMSAP
FLDKSFTMSL RGLYGCTSLI ILSHRGVYMT HFWEDPSFLD KESFKRQVLD VLENGYFSSH
YKGFHALVPL KPLIGPGGIL NPTTSPHFFV FAPKDRGILA ANPGINPASV PLMYPALVYN
LQSSVRDLTG AIPNLIYYDP NSETAQLYQR TKLGKVLLQY DPAISYIKVK GCYQQQALAR
LWFEGADDKL LPWPADANQI IPVAGASAVV KKRQGEACLL TSPTATASSV TVTSTTPMPT
LSTICLTSSL VGCSYTYQYV KAAFCTTTAP SLPAKCTAAP STTAPDTSSS LPTLPAQCVT
SSLVNCRWIF QYIDIADCPT TTSLLPASCT NPSKTSSKVP PATTTSPSLP ATTTLNLCYF
AQYYCDDLSS ECNAFDHGEY YWFVPNGSST CETVWGESSW IGFTKVKNPE DTTYHFPPSD
LDLSDFTKSA GCAFSPYGGD GSGSQSDSYY ESVSIGGVGE VRCTDHVLSN VAICYKAYEK
FEITAGQGRR EMVQLLTMVW NDDNYHN
//
