ID A0A094J3D1_9BACT Unreviewed; 793 AA.
AC A0A094J3D1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Putative diguanylate cyclase YegE {ECO:0000313|EMBL:KFZ27036.1};
DE EC=2.7.7.65 {ECO:0000313|EMBL:KFZ27036.1};
GN Name=yegE {ECO:0000313|EMBL:KFZ27036.1};
GN ORFNames=KQ78_00810 {ECO:0000313|EMBL:KFZ27036.1};
OS Candidatus Izimaplasma bacterium HR2.
OC Bacteria; Mycoplasmatota; Candidatus Izimaplasma.
OX NCBI_TaxID=1541960 {ECO:0000313|EMBL:KFZ27036.1, ECO:0000313|Proteomes:UP000029254};
RN [1] {ECO:0000313|EMBL:KFZ27036.1, ECO:0000313|Proteomes:UP000029254}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Skennerton C.T., Haroon M.F., Tyson G.W., Orphan V.J.;
RT "Phylogenomic Analysis of Candidatus Izimaplasma species: Representatives
RT from a Novel Mollicute Clade found in Ocean Sediments.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ27036.1}.
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DR EMBL; JRFF01000022; KFZ27036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094J3D1; -.
DR eggNOG; COG3275; Bacteria.
DR eggNOG; COG3437; Bacteria.
DR Proteomes; UP000029254; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0052621; F:diguanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00077; HDc; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR037522; HD_GYP_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR011620; Sig_transdc_His_kinase_LytS_TM.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR43155:SF2; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108; 1.
DR PANTHER; PTHR43155; CYCLIC DI-GMP PHOSPHODIESTERASE PA4108-RELATED; 1.
DR Pfam; PF07694; 5TM-5TMR_LYT; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13487; HD_5; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00471; HDc; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS51832; HD_GYP; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotidyltransferase {ECO:0000313|EMBL:KFZ27036.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000029254};
KW Transferase {ECO:0000313|EMBL:KFZ27036.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 69..94
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..190
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 328..400
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 487..617
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 608..793
FT /note="HD-GYP"
FT /evidence="ECO:0000259|PROSITE:PS51832"
SQ SEQUENCE 793 AA; 91106 MW; 12940E5E2C083E67 CRC64;
MNTEMILSFI SNILLLMSLA VVYSIFPYES RIKEIYKKII MGFVVAIIGV TIMYRQFELM
DGVLFDARAV AISVTAMFLG VIPTLIGGLA MIAYRIYLGG VGMLTGVLWI IFAATIGLFW
RHFRLKNPKF QKYNISWIEL YLIGFFVQVV MILLLLTLPN TLRDEVLNAV AFALLIVFPL
GSLIISEFML TQRFRFFQHL KTVSSEKQYK KLFSASQAMI FLIDPENGHF VDVNESAMKK
YNYTFKEFTQ LSVIDVSLLN PADSKQDVID SLSNELNHYM SRHITKDGVI LDVEVYSGSM
IIDNKEYVLS SVFDVTEKLE KERQFKDVDS KLRATLLSVG EGIVVTDDNH KITLINDKAL
EILGEIKRPI NKNICDIFRI YSNKSNVSFK ELFHKSIEDN KIFHSDITYS LLRNDNDEEI
YVDFSISPIN LEGKTNSGAI LVIRDETIEE ERKEQIRYIS QHDYLTELYN RFYFEEQLSR
LDTKRQLPLT IIMGDVNGLK LLNDAFSHIE GDKLLIEISK ILKKGIRQED ILARWGGDEF
AILLPQTSLE NSKKVYSRIK DLCNKSMYQT ITPSISLGCA TKISEDEHVN DIIKLAEERM
YHEKLLEGKE MRNDLVRALE KRLFERSADI RIHSENMVKY ADILGNELGI NEDGIKVLKQ
TARLHDIGLI ALDTAILTKI EPLDEREWDR IRSHSEIGSR IVLSINELQH ISKDILHHHE
RFDGTGYPTG LSGNSIPYFA RIISVIDAYD SMTTGRIYKE KISHKEAIEE IKRCSETQFD
PDIVKTFLKA FKG
//
