ID A0A094JG61_9GAMM Unreviewed; 1087 AA.
AC A0A094JG61;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Tricorn protease homolog {ECO:0000256|PIRNR:PIRNR036421};
DE EC=3.4.21.- {ECO:0000256|PIRNR:PIRNR036421};
GN ORFNames=HR45_06890 {ECO:0000313|EMBL:KFZ38217.1};
OS Shewanella mangrovi.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=1515746 {ECO:0000313|EMBL:KFZ38217.1, ECO:0000313|Proteomes:UP000029264};
RN [1] {ECO:0000313|EMBL:KFZ38217.1, ECO:0000313|Proteomes:UP000029264}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YQH10 {ECO:0000313|EMBL:KFZ38217.1,
RC ECO:0000313|Proteomes:UP000029264};
RA Liu Y., Zeng R.;
RT "Shewanella sp. YQH10.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Degrades oligopeptides. {ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496,
CC ECO:0000256|PIRNR:PIRNR036421}.
CC -!- SIMILARITY: Belongs to the peptidase S41B family.
CC {ECO:0000256|ARBA:ARBA00008524, ECO:0000256|PIRNR:PIRNR036421}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ38217.1}.
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DR EMBL; JPEO01000003; KFZ38217.1; -; Genomic_DNA.
DR RefSeq; WP_037441065.1; NZ_JPEO01000003.1.
DR AlphaFoldDB; A0A094JG61; -.
DR STRING; 1515746.HR45_06890; -.
DR eggNOG; COG0793; Bacteria.
DR eggNOG; COG4946; Bacteria.
DR OrthoDB; 9758793at2; -.
DR Proteomes; UP000029264; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-UniRule.
DR CDD; cd00988; PDZ_CTP_protease; 1.
DR CDD; cd07562; Peptidase_S41_TRI; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR Gene3D; 3.30.750.44; -; 1.
DR Gene3D; 2.120.10.60; Tricorn protease N-terminal domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR011659; PD40.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR005151; Tail-specific_protease.
DR InterPro; IPR028204; Tricorn_C1.
DR InterPro; IPR029414; Tricorn_PDZ.
DR InterPro; IPR012393; Tricorn_protease.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR43253; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR PANTHER; PTHR43253:SF1; TRICORN PROTEASE HOMOLOG 2-RELATED; 1.
DR Pfam; PF07676; PD40; 2.
DR Pfam; PF03572; Peptidase_S41; 1.
DR Pfam; PF14684; Tricorn_C1; 1.
DR Pfam; PF14685; Tricorn_PDZ; 1.
DR PIRSF; PIRSF036421; Tricorn_protease; 1.
DR SMART; SM00228; PDZ; 1.
DR SMART; SM00245; TSPc; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR SUPFAM; SSF69322; Tricorn protease domain 2; 1.
DR SUPFAM; SSF69304; Tricorn protease N-terminal domain; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|PIRNR:PIRNR036421};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR036421};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PIRNR:PIRNR036421};
KW Reference proteome {ECO:0000313|Proteomes:UP000029264};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825,
KW ECO:0000256|PIRNR:PIRNR036421}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1087
FT /note="Tricorn protease homolog"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001900616"
FT DOMAIN 765..844
FT /note="PDZ"
FT /evidence="ECO:0000259|SMART:SM00228"
FT DOMAIN 833..1038
FT /note="Tail specific protease"
FT /evidence="ECO:0000259|SMART:SM00245"
FT ACT_SITE 747
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 969
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT ACT_SITE 1027
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-1"
FT SITE 970
FT /note="Transition state stabilizer; via amide nitrogen"
FT /evidence="ECO:0000256|PIRSR:PIRSR036421-3"
SQ SEQUENCE 1087 AA; 120549 MW; 29FA1F9285219663 CRC64;
MKLRHSVACC LLALGVSAIT GVANAAQGYY RAPDLHGNTL VFTAEGDLWT QQLGQAHASR
LTSLPAEELH GKISPDGKSL AFVANYDGVD EVYTIPLAGG SAKRVTFENS RVRVQGWTAK
GEILYSTDNA DGPSNFWVLR TVNPSSLVTQ DIPLADAVQG AVDAAGEYVY FVRFGLQVTG
DNARVYRGGA KGELWRYKLG SKQEAQCLSN AHDGSIRAPM LWQNRIYFVS DESGNANIWS
MSLDGKDAKQ LTHYQDYEVR SPSLDNGRIV FQLGADIHLL DIASGKDVVE AIDLQSDFPE
RHERWVNNPL EYANDFNLSP SGNKVVLTAR SHVAIAGTDR TRLVELPSDG SFRMRNAVMS
QDGKHVYAIS DKSGEQEIWQ YAADGSETAK QLTKDGKSMR MSLVLSPNGR YLASDDYEGN
LWLLDLKKGT QRKIASNNEG LAPYQDIVWS PDSRYLALTK TEIGTPRPQI VLLSLDDGKT
AVLTSDKYES FSPAFSTDGK WLYFLSNRTF NSTPSSPWGD RNLGPVFDKR TDIYALALDK
HAQFPFAHPN ELTDFQKSTS NDDDENASVK VQVDWQGITA RLWQVPVTAD NFNRLQINAK
GLYVASDTDR SVKFIKYDHD KAKVETFAKD VRGYQLSNDG EKIFIYKGTK PGQMLIVDAG
DKLPSDLDDA KVRFDGWKLA IQPQQEWQQM FEDAWLMHRE SFFDKHMRGV DWAATKQKYL
PLLARVTDRH ELADIFTQMM GELDALHSQV RGGDFAKDEA MPTPAALGAK LTQTADGVAI
SHIYRNDPEL PQRASPLATP GVDAKEGDII IGVNGRSVNS IAEVTSLLRN QADKQVLLQL
QRNDKTLKTV VVPVPLWADG QLRYLDWVNS NANKVSKASD GKIGYLHLYA MGASDIANFA
REFYANYDKD GLIIDVRRNR GGNIDSWIIE KLLRKAWMFW QPTHGTPYPN MQQAFRGHLV
VLTDELTYSD GETFSAGIKA LGIAPLIGKR TAGAGVWLSG RNRLTDGGMS RVAEYPQYAM
DGRWIVEGQG ISPNIEVDNL PVATFEGKDA QLQKAISYLQ QQLAKAPVAP LQAQPMPKRG
EAQDVRP
//
