ID A0A094JN51_9PEZI Unreviewed; 936 AA.
AC A0A094JN51;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 39.
DE RecName: Full=DH domain-containing protein {ECO:0000259|PROSITE:PS50010};
GN ORFNames=V502_08097 {ECO:0000313|EMBL:KFZ10478.1};
OS Pseudogymnoascus sp. VKM F-4520 (FW-2644).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420915 {ECO:0000313|EMBL:KFZ10478.1, ECO:0000313|Proteomes:UP000029308};
RN [1] {ECO:0000313|EMBL:KFZ10478.1, ECO:0000313|Proteomes:UP000029308}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4520 (FW-2644) {ECO:0000313|Proteomes:UP000029308};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ10478.1}.
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DR EMBL; JPKE01002843; KFZ10478.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094JN51; -.
DR STRING; 1420915.A0A094JN51; -.
DR HOGENOM; CLU_007879_1_0_1; -.
DR OrthoDB; 23973at2759; -.
DR Proteomes; UP000029308; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd05992; PB1; 1.
DR CDD; cd13246; PH_Scd1; 1.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR010481; Cdc24/Scd1_N.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR001331; GDS_CDC24_CS.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR47339; CELL DIVISION CONTROL PROTEIN 24; 1.
DR PANTHER; PTHR47339:SF1; CELL DIVISION CONTROL PROTEIN 24; 1.
DR Pfam; PF06395; CDC24; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF15411; PH_10; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF54277; CAD & PB1 domains; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS00741; DH_1; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000029308}.
FT DOMAIN 198..373
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 444..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 583..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 621..802
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 590..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 631..649
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 657..686
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 697..733
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 758..788
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 936 AA; 104254 MW; 4CAC814B33BAE3C3 CRC64;
MSSSTLTSAS SASLNTLSTS TTISQNGSNV VATNNIINQR ADASRSLYQI CVSLRQRLLL
VPGFEQHLQE LDDDEISGDD DDPVTSLWRC LKKGYPLMTI YNALQPPEAL HVDDKVSDAK
KPKSAASKFV LACLKDLKLP PEEVFVLNDL FGDDTTGFVK VTQVLNVVLD VAEQRGLLLT
PEAEAETPNA AVGGKMSYRD HVVRELVDTE RKYVQDLENL HELKKQIEQK GVIPGDVVHA
IFLNINAILD FQRRFLIRIE TTNSQPDARQ EWGAPFVFHE ESFGIYQPFI ANQRRAADIA
KREFDKISMA DHPVVVDFNT LDGFLLKPMQ RLVKYPLLLK DLRDKTNADD QTKAELTAGI
EASNRVLHQA NAAVDRELRN EALVDLCTRV DDWKNHDINQ FGDLLLHGVF TVITGKSDLE
KEYTIYLFER ILLCCKEVNP NKATKDKLMG GGQKKDKKDK SSKTIKLQLK GRIFMTNVTD
VVSMVKPGSY TVQIWWKGDP GIENFMIRFS HEEVMKKWSA AVDKQRKDCL DREQGPEVGT
PEFAWMQVQK EPIHNPYAQP EDEDDDDDYP QLANSGVFAE QAALPEPNAF GMNRNTSSTS
LRSRSTTGES IQSIAGVVRQ APPQFPMGPQ PPLSLQTQMP LQTPPGTRGG DSYFSPVAES
PASSRASQNS MFPFPRQGSL TGNWEDHSRY TAPAIGRTPS RESQQSINYR NPQRPSLPVM
SSQQAQMVNA ARRRNDSQPV PAVPGIPPHL HPAYDSGIPR SSNGSPINGI PVRSATQSPG
TQRDRSQPPQ AGYPAVPPTY LRSNTTPVLA TMKAEDRTQT MSPPLNNSLP GMDMGLPTQL
KVKVNCDGNY VTLVVAFNIT YQSLIDRIDA KVGRFSNNAI ARGTMRLRYQ DEDGDYVTIE
SDDDIHIAFQ EWREQQIEGL KNGMLGEIEL FCASIE
//
