ID A0A094KBA5_9PEZI Unreviewed; 485 AA.
AC A0A094KBA5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V501_00983 {ECO:0000313|EMBL:KFZ18843.1};
OS Pseudogymnoascus sp. VKM F-4519 (FW-2642).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1420914 {ECO:0000313|EMBL:KFZ18843.1, ECO:0000313|Proteomes:UP000029315};
RN [1] {ECO:0000313|EMBL:KFZ18843.1, ECO:0000313|Proteomes:UP000029315}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-4519 (FW-2642) {ECO:0000313|Proteomes:UP000029315};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFZ18843.1}.
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DR EMBL; JPKD01000324; KFZ18843.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094KBA5; -.
DR STRING; 1420914.A0A094KBA5; -.
DR HOGENOM; CLU_014379_3_1_1; -.
DR Proteomes; UP000029315; Unassembled WGS sequence.
DR GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR033452; GH30_C.
DR InterPro; IPR001139; Glyco_hydro_30.
DR InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR Pfam; PF02055; Glyco_hydro_30; 1.
DR Pfam; PF17189; Glyco_hydro_30C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|RuleBase:RU361188};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW Reference proteome {ECO:0000313|Proteomes:UP000029315};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..485
FT /note="Glycosyl hydrolase family 30 TIM-barrel domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001906063"
FT DOMAIN 68..407
FT /note="Glycosyl hydrolase family 30 TIM-barrel"
FT /evidence="ECO:0000259|Pfam:PF02055"
FT DOMAIN 417..476
FT /note="Glycosyl hydrolase family 30 beta sandwich"
FT /evidence="ECO:0000259|Pfam:PF17189"
SQ SEQUENCE 485 AA; 52597 MW; 155E07CB0011545D CRC64;
MQLSSLILFA CHAAALGILK PKAFASTADG KYKISSYAAP VKGHGNPGSS QTWSLSIDDT
KTGHKQKVTG FGASLTETTV DVFNKLPPLK LAKLLVELMT PLGNNFGIMR HTIGSSDLSP
EPAMSYDDNG GNAGKVDLTL AHFNIGERGE AMVKMLNAMK LLDWDLTILG SAWGPPGWMM
NGGMLVGASN NTLNHKYGKQ YGEYFAKYIQ AFERGGVHID AITIQNEPLN NNTGMPTMVI
QPDESGQIIR DYVGPALKRA GLNTEIWAYD HNTDRPDYPQ AVMDIAPQYV NTAAWHCYAN
PIDWTVLTDF YKNNSHVEGF KQFHTECWTS NIYTGWNQAA DFVMGPMQNY AEGSLAWTLA
TDTNNGPCLD TPGACCTCTG LVVIDTVAGT YNLTTDYYMM GQFSKFMPRG ATVLSGIGSS
TNADGVGVES VASINPDLTR SVVIENKFTN PVYVSLTTKS GETWSGKVEA QSVTTWVLPP
NLLTL
//
