ID A0A094KKT9_PODCR Unreviewed; 832 AA.
AC A0A094KKT9;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE SubName: Full=DNA repair protein complementing XP-C cells {ECO:0000313|EMBL:KFZ59190.1};
DE Flags: Fragment;
GN ORFNames=N338_00944 {ECO:0000313|EMBL:KFZ59190.1};
OS Podiceps cristatus (Great crested grebe).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Podicipediformes; Podicipedidae; Podiceps.
OX NCBI_TaxID=345573 {ECO:0000313|EMBL:KFZ59190.1, ECO:0000313|Proteomes:UP000053854};
RN [1] {ECO:0000313|EMBL:KFZ59190.1, ECO:0000313|Proteomes:UP000053854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N338 {ECO:0000313|EMBL:KFZ59190.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the XPC family. {ECO:0000256|ARBA:ARBA00009525}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KL260185; KFZ59190.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094KKT9; -.
DR Proteomes; UP000053854; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd21393; sm_acid_XPC-like; 1.
DR Gene3D; 2.20.20.110; Rad4, beta-hairpin domain BHD1; 1.
DR Gene3D; 3.30.70.2460; Rad4, beta-hairpin domain BHD3; 1.
DR Gene3D; 3.90.260.10; Transglutaminase-like; 2.
DR InterPro; IPR018327; BHD_2.
DR InterPro; IPR004583; DNA_repair_Rad4.
DR InterPro; IPR018026; DNA_repair_Rad4-like.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR018325; Rad4/PNGase_transGLS-fold.
DR InterPro; IPR018326; Rad4_beta-hairpin_dom1.
DR InterPro; IPR018328; Rad4_beta-hairpin_dom3.
DR InterPro; IPR042488; Rad4_BHD3_sf.
DR InterPro; IPR036985; Transglutaminase-like_sf.
DR NCBIfam; TIGR00605; rad4; 1.
DR PANTHER; PTHR12135:SF0; DNA REPAIR PROTEIN COMPLEMENTING XP-C CELLS; 1.
DR PANTHER; PTHR12135; DNA REPAIR PROTEIN XP-C / RAD4; 1.
DR Pfam; PF10403; BHD_1; 1.
DR Pfam; PF10404; BHD_2; 1.
DR Pfam; PF10405; BHD_3; 1.
DR Pfam; PF03835; Rad4; 1.
DR SMART; SM01030; BHD_1; 1.
DR SMART; SM01031; BHD_2; 1.
DR SMART; SM01032; BHD_3; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053854}.
FT DOMAIN 524..576
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01030"
FT DOMAIN 578..638
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01031"
FT DOMAIN 645..719
FT /note="Rad4 beta-hairpin"
FT /evidence="ECO:0000259|SMART:SM01032"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 205..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 761..832
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 212..232
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 241..266
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 270..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..324
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..342
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 353..367
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 801..832
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFZ59190.1"
FT NON_TER 832
FT /evidence="ECO:0000313|EMBL:KFZ59190.1"
SQ SEQUENCE 832 AA; 94903 MW; D1B740CB38FD2061 CRC64;
NDDDDESEDE WEDVEELQEP ATDKLEEAAV LPAVVLPSNP VEIEIETPEQ VKKRERREKR
KAEFEMYLRR MVKRFSKEVR EDTHKVHLLC LLANGFYRNR ICSQPDLHAI GLSIIPTHFT
KVPADQVDLL YLSNLVKWFV GTFTVNDELS TEKGEPLQLT LERRFAVYAA RDDEELVHIF
LIILRALQLL CRLVLSFQPI PLKETRAKGK SSSKRQSLSG TSEGQESSAT TPKAVAKKCP
CKKAKRDEKS SESKEDNKEP KKPKTTQSKR TCKSKLTPGS QGQKATSNEE SSLAEKDVLV
KPKNDRRRRV ASKVCYKEES GSDEGSVSDF EVSEEESDLS DEDFETVSKR RRSSLGSQKS
KVTAIKSPKP ETSELRLSKT SCGAEPRPAK STAPTLPHVR RNKIISSDEE DGQQEAGKVM
GTDQWLEVFL EREDKWVCVD CVHGNVGQPQ LCFTYATKPL SYIVGFDNDG SVRDVTQRYD
PVWMTATRKS RVDPEWWEVT LQPYRSPYVE RDKKEENEFQ VKLQDQPLPT AIGEYKNHPL
YALKRHLLKY QAIYPESAAI LGYCRGEAVY SRDCVHTLHS KDTWLKKARV VRIGEVPYKM
VKGFSNQARK ARLAEPANRD KEDLALFGRW QTEEYQPPIA VDGKVPRNEY GNVYLFLPSM
LPIGCVQLRL PNLNRLARKL DIDCAQAITG FDFHGGYSHP VTDGYVVCEE YKEVLVAAWE
NEQAEIEKKE KEKREKRALG NWKLLTKGLL IRERLKQRYS FKTEPSAPET EKGTGFSSDE
EGGPSSETAV GDVAISWPQN RQLEKKKEEK TTRKSKREKK GEAAQLFPFE KL
//
