ID   A0A094LDN2_ANTCR        Unreviewed;       872 AA.
AC   A0A094LDN2;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   SubName: Full=Nucleotide-binding oligomerization domain-containing protein 1 {ECO:0000313|EMBL:KFZ62094.1};
GN   ORFNames=N321_08946 {ECO:0000313|EMBL:KFZ62094.1};
OS   Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Caprimulgiformes;
OC   Caprimulgidae; Antrostomus.
OX   NCBI_TaxID=279965 {ECO:0000313|EMBL:KFZ62094.1, ECO:0000313|Proteomes:UP000053620};
RN   [1] {ECO:0000313|EMBL:KFZ62094.1, ECO:0000313|Proteomes:UP000053620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N321 {ECO:0000313|EMBL:KFZ62094.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00004187}. Cell membrane
CC       {ECO:0000256|ARBA:ARBA00004193}; Lipid-anchor
CC       {ECO:0000256|ARBA:ARBA00004193}. Lateral cell membrane
CC       {ECO:0000256|ARBA:ARBA00004124}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004635}; Lipid-anchor
CC       {ECO:0000256|ARBA:ARBA00004635}.
CC   -!- SIMILARITY: Belongs to the NOD1-NOD2 family.
CC       {ECO:0000256|ARBA:ARBA00038296}.
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DR   EMBL; KL355866; KFZ62094.1; -; Genomic_DNA.
DR   RefSeq; XP_010170168.1; XM_010171866.1.
DR   AlphaFoldDB; A0A094LDN2; -.
DR   GeneID; 104527996; -.
DR   KEGG; acar:104527996; -.
DR   CTD; 10392; -.
DR   OrthoDB; 3087860at2759; -.
DR   Proteomes; UP000053620; Unassembled WGS sequence.
DR   GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
DR   GO; GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
DR   CDD; cd08324; CARD_NOD1_CARD4; 1.
DR   Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001315; CARD.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRP_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR24106; NACHT, LRR AND CARD DOMAINS-CONTAINING; 1.
DR   PANTHER; PTHR24106:SF18; NUCLEOTIDE-BINDING OLIGOMERIZATION DOMAIN-CONTAINING PROTEIN 1; 1.
DR   Pfam; PF00619; CARD; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   SMART; SM00368; LRR_RI; 5.
DR   SUPFAM; SSF47986; DEATH domain; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS50209; CARD; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Immunity {ECO:0000256|ARBA:ARBA00022859};
KW   Innate immunity {ECO:0000256|ARBA:ARBA00022588};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Palmitate {ECO:0000256|ARBA:ARBA00023139};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053620};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          27..95
FT                   /note="CARD"
FT                   /evidence="ECO:0000259|PROSITE:PS50209"
FT   DOMAIN          201..402
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   872 AA;  99918 MW;  78F8D09AF538F92A CRC64;
     MEGQLCGNLE ICVEKPPGTS PPSFIALLKV YRELLVSRIR NTQCLIDNLI KNEYFSTEDA
     EIVVQFPTQA DKVRKILDLV QSKGEEVSEY FIRVLHKVTD AYYELQPWLG EIGYEPSENI
     CSKPVVNTDP VSRYCQKLRY ELGRESKFVM SYAQREEMLL EEIYSNSTME LVSFTNESLG
     KVCQLEALFD DAVGVINEDG ETVYVFGDAG IGKSILLQKI QSLWARKELD IGAKFFFHFR
     CRMFSCFKED EAICLKDLLF KYNCYPDQDP TEVFHHILQF PHTVLFTFDG FDEIYSNFDL
     SSVPEMCSPN EPIHPLVLLV SLLRGKLLKG SKKILTARTG TEIQRNIIRK KVLLRGFSSN
     NLKEYAAMIF KEEGQRRLVL NKLEANPNLC SLCSVPLFCW IIFKCYEHFH SMFDSYELPD
     CSVTLTDVFL LMIEVHLNRS LKTSLLKNNT RSQSEMFRSK KETLLALGKM AYKGMENSFF
     IFEQEDISSM NISEEDLQLG FLRTVKHYSG CDSQSSYEFL HLTLQSFFTA LFLVVEEKVS
     SKELLQFFNE CSSTETAQPT CLHIPWLKKQ LAGEDPFRNN EHFHFTNLFL CGLLSRSKQK
     LFRHLVLPAV IKKKRKTLIT YLGDSMKSHL KGVTRSRLRN YNRIQVQPNF IWMLRCLYET
     QSEKVGKLAA KRMHANYIKL TYCNAYSADC SAISFVAHHF QKQLALDLDN NNINDYGVKQ
     LLPCFSKLAV IRLSVNQVTD HGVRILYEEL SKYQIVTFLG LYNNQITDVG AEYVAKLIEE
     CSSLEYVKIG ANKITSEGGK CLAQAIQKSK TMFEIGMWGN QVGDEGAKAF AEALRNHPRL
     TNVSLALNGI TTEGGKCIAE AMQHNNSVKI FW
//