ID A0A094N105_ANTCR Unreviewed; 674 AA.
AC A0A094N105;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma {ECO:0000313|EMBL:KFZ60396.1};
DE Flags: Fragment;
GN ORFNames=N321_12188 {ECO:0000313|EMBL:KFZ60396.1};
OS Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Caprimulgiformes;
OC Caprimulgidae; Antrostomus.
OX NCBI_TaxID=279965 {ECO:0000313|EMBL:KFZ60396.1, ECO:0000313|Proteomes:UP000053620};
RN [1] {ECO:0000313|EMBL:KFZ60396.1, ECO:0000313|Proteomes:UP000053620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N321 {ECO:0000313|EMBL:KFZ60396.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the PI3/PI4-kinase family. Type III PI4K
CC subfamily. {ECO:0000256|ARBA:ARBA00006209}.
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DR EMBL; KL353375; KFZ60396.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094N105; -.
DR Proteomes; UP000053620; Unassembled WGS sequence.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0046854; P:phosphatidylinositol phosphate biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR Gene3D; 1.25.40.70; Phosphatidylinositol 3-kinase, accessory domain (PIK); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR018936; PI3/4_kinase_CS.
DR InterPro; IPR002420; PI3K-type_C2_dom.
DR InterPro; IPR001263; PI3K_accessory_dom.
DR InterPro; IPR042236; PI3K_accessory_sf.
DR InterPro; IPR015433; PI_Kinase.
DR PANTHER; PTHR10048:SF29; PHOSPHATIDYLINOSITOL 3-KINASE C2 DOMAIN-CONTAINING SUBUNIT GAMMA; 1.
DR PANTHER; PTHR10048; PHOSPHATIDYLINOSITOL KINASE; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF00613; PI3Ka; 1.
DR SMART; SM00145; PI3Ka; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51547; C2_PI3K; 1.
DR PROSITE; PS00915; PI3_4_KINASE_1; 1.
DR PROSITE; PS00916; PI3_4_KINASE_2; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
DR PROSITE; PS51545; PIK_HELICAL; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000053620};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 90..239
FT /note="C2 PI3K-type"
FT /evidence="ECO:0000259|PROSITE:PS51547"
FT DOMAIN 254..426
FT /note="PIK helical"
FT /evidence="ECO:0000259|PROSITE:PS51545"
FT DOMAIN 495..674
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFZ60396.1"
FT NON_TER 674
FT /evidence="ECO:0000313|EMBL:KFZ60396.1"
SQ SEQUENCE 674 AA; 77052 MW; 683817E39655234D CRC64;
DDQRWFSVNQ LLEDHCAWRL TQQNLVSILM KYRGQVEYLF QNEQQRTVDN VIEVAKAICG
VLCFVETRDI TAAVQKLRAV PLVKAQVTLI EAAVTELSMA ISCLIHVYSS SFDTNFQLAS
IPKSPSCADI SLDSQLSFTV YAAHNIPETW VDRINFPLRI KALPRETMLT IKLLGVNSAS
KNTEVLAWTC TPLYPKERLI HGTVLLSMTL YSTLTTTMIT PGICSTDTPT SVVLQIDFPE
TDLEFIKPEP EEGRGDLEEP TKDCLKHITR LSQTHSLLLL SEQQRRILWF YRSYCNDQNC
SLPLVLGSAP SWDQTTVSEM YGVLRRWRFF NPLEALGLLT FSFPDQDIRR RAVQQIENLT
NDELLEYLPQ LVQVRKKLLA KEVFLLNRSL QSIQVAHQLY WLLKNAQNEV HFKIWYQKLL
AALQFCAGKS LNNEFSKEEK LIRILEDIAE KVKAASDPKR KEVLKVELNK LQRFFQEVKV
CRLPLNPALV VQGIEADSCS YFTSNAFPLK ISFISANVPS GNINVIFKIG DDLRQDMLVL
QIIRVMDSIW LQEGLDMQMI VYRCLSTGKS QGLVQMVPDA TTLAKIHRKS GLIGPLKENT
IKKWFHHHHP LESSYQEAIR NFFYSCAGWC VVTFILGVCD RHSDNIMLTN AGHMFHIDFG
RFLGHAQTFG SIRR
//
