ID A0A094N1J0_PODCR Unreviewed; 291 AA.
AC A0A094N1J0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Mitochondrial fission factor {ECO:0000256|RuleBase:RU368040};
GN ORFNames=N338_09471 {ECO:0000313|EMBL:KFZ60561.1};
OS Podiceps cristatus (Great crested grebe).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Podicipediformes; Podicipedidae; Podiceps.
OX NCBI_TaxID=345573 {ECO:0000313|EMBL:KFZ60561.1, ECO:0000313|Proteomes:UP000053854};
RN [1] {ECO:0000313|EMBL:KFZ60561.1, ECO:0000313|Proteomes:UP000053854}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N338 {ECO:0000313|EMBL:KFZ60561.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in mitochondrial and peroxisomal fission.
CC Promotes the recruitment and association of the fission mediator
CC dynamin-related protein 1 (DNM1L) to the mitochondrial surface.
CC {ECO:0000256|RuleBase:RU368040}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004211}; Single-
CC pass type IV membrane protein {ECO:0000256|ARBA:ARBA00004211}.
CC Mitochondrion outer membrane {ECO:0000256|RuleBase:RU368040}; Single-
CC pass type IV membrane protein {ECO:0000256|RuleBase:RU368040}.
CC Peroxisome {ECO:0000256|RuleBase:RU368040}.
CC -!- SIMILARITY: Belongs to the Tango11 family.
CC {ECO:0000256|ARBA:ARBA00009806, ECO:0000256|RuleBase:RU368040}.
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DR EMBL; KL263050; KFZ60561.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094N1J0; -.
DR Proteomes; UP000053854; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell.
DR GO; GO:0000266; P:mitochondrial fission; IEA:UniProtKB-UniRule.
DR GO; GO:0090141; P:positive regulation of mitochondrial fission; IEA:UniProtKB-UniRule.
DR GO; GO:0090314; P:positive regulation of protein targeting to membrane; IEA:UniProtKB-UniRule.
DR InterPro; IPR039433; Mff-like_dom.
DR InterPro; IPR008518; Mff/Tango-11.
DR PANTHER; PTHR16501:SF17; MITOCHONDRIAL FISSION FACTOR; 1.
DR PANTHER; PTHR16501; UNCHARACTERIZED; 1.
DR Pfam; PF05644; Miff; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU368040};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128,
KW ECO:0000256|RuleBase:RU368040};
KW Mitochondrion outer membrane {ECO:0000256|RuleBase:RU368040};
KW Peroxisome {ECO:0000256|RuleBase:RU368040};
KW Reference proteome {ECO:0000313|Proteomes:UP000053854};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU368040};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU368040}.
FT TRANSMEM 271..289
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU368040"
FT DOMAIN 1..291
FT /note="Mff-like"
FT /evidence="ECO:0000259|Pfam:PF05644"
FT REGION 105..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 242..269
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 291 AA; 33129 MW; 9323FF1EB0B1D384 CRC64;
MAEINRLQYE MEYTEGISQR MRVPEKLKVA PQNADLEKGI QEGFPNASVT MQVPERIVVA
GNSEAIPFSR PPDLDLLQST PFKPLALKTP PRVISLSDRP LDFLDLEKPP QQTPQNEEAM
GRLKRERSMS ENATRQNGQL ARNDSIVTPS LQQARVCPPN MLPEDGTNLY SARGILSFIQ
SSTRRAYQQV LDVLDENRRP VLRGGSAATT SSNPHHDNTR YGLSNLDTTL EGTPDDMTVV
DAASLRRQII KLNRRLQLLE EENKERAKRE MIMYSITVAF WLLNSWLWFR R
//
