ID A0A094N5S1_ANTCR Unreviewed; 1074 AA.
AC A0A094N5S1;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Integrin alpha-6 {ECO:0000313|EMBL:KFZ61991.1};
DE Flags: Fragment;
GN ORFNames=N321_04867 {ECO:0000313|EMBL:KFZ61991.1};
OS Antrostomus carolinensis (Chuck-will's-widow) (Caprimulgus carolinensis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Caprimulgiformes;
OC Caprimulgidae; Antrostomus.
OX NCBI_TaxID=279965 {ECO:0000313|EMBL:KFZ61991.1, ECO:0000313|Proteomes:UP000053620};
RN [1] {ECO:0000313|EMBL:KFZ61991.1, ECO:0000313|Proteomes:UP000053620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N321 {ECO:0000313|EMBL:KFZ61991.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR EMBL; KL355674; KFZ61991.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A094N5S1; -.
DR Proteomes; UP000053620; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF9; INTEGRIN ALPHA-6; 1.
DR Pfam; PF13517; FG-GAP_3; 1.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 4.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR PROSITE; PS51470; FG_GAP; 4.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000053620};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT TRANSMEM 999..1021
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 223..280
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 281..342
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 343..398
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 402..461
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 446..608
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 610..775
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT DOMAIN 781..987
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFZ61991.1"
FT NON_TER 1074
FT /evidence="ECO:0000313|EMBL:KFZ61991.1"
SQ SEQUENCE 1074 AA; 120223 MW; 1A18B6875278F8FB CRC64;
LLVGAPREKA FPSQQANRTG GLYSCDIASP NTRCTRVIFD EETDPKMESK EDQWMGVTVQ
SQGPGGNVVT CAHRYEKRQY VNTVQETRDI IGRCYVLSQD LTIKDDMDNG VWSFCDGRLR
GHEKFGSCQQ GVAATFTRDY HYIVFGAPGT YNWKGVVRAE QKNQTFYDLG IFDDGPYEVG
DESRQDKNLV PVPANSYLGL LFLTAVSDTH PDQFVYKTLP PGIQVDKSVD VMMNSYLGFS
LDSGKGIVSQ DEMTFVSGAP RANHSGAVVL LKKEKNQRAL SLEHMFEGEG LASSFGYDVA
VVDLNNDGWQ DIVVGAPQYF DRSGDIGGAV YIYINQQGKW EGVKPIRLNG TTDSMFGLAV
ENVGDINQDG YPDIAVGAPY DGFGKVYVYH GSKNGINTKP AQILDGEKTG TNFFGYSIAG
NMDLDKNSYP DIAVGSLSDS VSVFRSRPVI SIRRSITVQP DRIDLKKKNP EDPSEIWMDV
KACFQYTANP SDLNPRIKIN YTFEAENERR QLGLPSRVRF KDHLSDQFTA STTLRGQNSK
ECVTTKLVLQ EKIKDKLRPI PISVSVKIAG LESSSPSTRK ERALPDLIPI LNSNESETKT
TKVEFLKEGC GDDNECHSNL KLQYRFCARE GNEDRFTYLP IENGMPVLVL KDQKDIALEI
TVTNNPSDAK NPQKDGEDAY EAKLIATFPD SLTYSAFREM RGYPEKQLTC GANQNGSQAE
CELGNPFKRN SNVTFYLILS TTKVNVDTTD LDINLKLETT STQVNSTPIT ASAKVVLELL
LSLTGVAKPS QVYFGGNIVG ESAMKSEDHI GNLIEYEFRV TNLGRPLKTF GTASLDIQWP
KEISNGKWLL YLMKIDSKGL EKVSCQPERE INSLHVAESH NSRRKREVAE KQITDSKTFS
LFSERKYKTL DCNVNARCVD IKCPLKGLDS KASIVLRSRL WNSTFLEEYS KMNYLDILVR
ASISVPAAAK NVKLSNEVAQ VRVTVFPVKP VALYTGVPWW IISVAIFAGI LMLALLVFLL
WKCGFFQRSR YEDSVPRYHA VRIRKEERQI KDGKCKDLET KQWFTKWNEN ESYS
//
